hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09775.1

Complex Portal: CPX-11627

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
ATP5PD	ATP synthase subunit d, mitochondrial (ATPase subunit d) (ATP synthase peripheral stalk subunit d)	5	UniProt NCBI
ATP5F1D	ATP synthase subunit delta, mitochondrial (ATP synthase F1 subunit delta) (F-ATPase delta subunit)	5	UniProt NCBI
SLC43A3	Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3)	5	UniProt NCBI
ATP5PF	ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6) (ATP synthase peripheral stalk subunit F6)	5	UniProt NCBI
P2RY1	P2Y purinoceptor 1 (P2Y1) (ADP receptor) (Purinergic receptor)	5	UniProt NCBI
ZFYVE27	Protrudin (Spastic paraplegia 33 protein) (Zinc finger FYVE domain-containing protein 27)	5	UniProt NCBI
ATP5PB	ATP synthase F(0) complex subunit B1, mitochondrial (ATP synthase peripheral stalk-membrane subunit b) (ATP synthase proton-transporting mitochondrial F(0) complex subunit B1) (ATP synthase subunit b) (ATPase subunit b)	5	UniProt NCBI
ATP5F1C	ATP synthase subunit gamma, mitochondrial (ATP synthase F1 subunit gamma) (F-ATPase gamma subunit)	5	UniProt NCBI
SLC19A2	Thiamine transporter 1 (ThTr-1) (ThTr1) (Solute carrier family 19 member 2) (Thiamine carrier 1) (TC1)	5	UniProt NCBI
ATP5IF1	ATPase inhibitor, mitochondrial (ATP synthase F1 subunit epsilon) (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1)	5	UniProt NCBI
ATP5F1B	ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta)	5	UniProt NCBI
CERS6	Ceramide synthase 6 (CerS6) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291)	5	UniProt NCBI
NTSR1	Neurotensin receptor type 1 (NT-R-1) (NTR1) (High-affinity levocabastine-insensitive neurotensin receptor) (NTRH)	5	UniProt NCBI
MT-ATP6	ATP synthase subunit a (F-ATPase protein 6)	5	UniProt NCBI
ATP5F1E	ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon) (ATP synthase F1 subunit epsilon)	5	UniProt NCBI
MT-ATP8	ATP synthase protein 8 (A6L) (F-ATPase subunit 8)	5	UniProt NCBI
ATP5PO	ATP synthase subunit O, mitochondrial (ATP synthase peripheral stalk subunit OSCP) (Oligomycin sensitivity conferral protein) (OSCP)	5	UniProt NCBI
ATP5ME	ATP synthase subunit e, mitochondrial (ATPase subunit e) (ATP synthase membrane subunit e) [Cleaved into: ATP synthase subunit e, mitochondrial, N-terminally processed]	4	UniProt NCBI
ATP5MG	ATP synthase subunit g, mitochondrial (ATPase subunit g) (ATP synthase membrane subunit g)	4	UniProt NCBI
ATP5MC1	ATP synthase F(0) complex subunit C1, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase membrane subunit c locus 1) (ATP synthase proteolipid P1) (ATP synthase proton-transporting mitochondrial F(0) complex subunit C1) (ATPase protein 9) (ATPase subunit c)	5	UniProt NCBI
TMEM120A	Ion channel TACAN (Transmembrane protein 120A) (Transmembrane protein induced by tumor necrosis factor alpha)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:563	9.49067113126e-32	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	F1F0-ATP synthase, mitochondrial
REAC:R-HSA-163210	4.81893831431e-24	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	Formation of ATP by chemiosmotic coupling
REAC:R-HSA-8949613	3.28903490863e-21	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	Cristae formation
GO:0005753	6.28325648947e-21	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	mitochondrial proton-transporting ATP synthase complex
GO:0045259	6.28325648947e-21	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	proton-transporting ATP synthase complex
GO:0046933	3.31259193036e-19	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	proton-transporting ATP synthase activity, rotational mechanism
WP:WP111	2.50110542919e-18	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	Electron transport chain OXPHOS system in mitochondria
GO:0015252	8.48751696183e-18	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	proton channel activity
GO:0016469	4.36968016435e-17	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	proton-transporting two-sector ATPase complex
REAC:R-HSA-1592230	3.76930730664e-16	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	Mitochondrial biogenesis
KEGG:00190	2.74619729813e-15	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	Oxidative phosphorylation
GO:0015986	6.89613114863e-15	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	proton motive force-driven ATP synthesis
REAC:R-HSA-163200	1.32346228744e-14	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
GO:0006754	3.69658117104e-14	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	ATP biosynthetic process
GO:0009145	4.76615945854e-14	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	purine nucleoside triphosphate biosynthetic process
GO:0009206	4.76615945854e-14	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	purine ribonucleoside triphosphate biosynthetic process
GO:0009201	8.75596837703e-14	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	ribonucleoside triphosphate biosynthetic process
GO:0009142	1.23975266754e-13	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	nucleoside triphosphate biosynthetic process
WP:WP623	2.15777650332e-13	0.444444444444	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1E ATP5PD ATP5MG MT-ATP6	Oxidative phosphorylation
GO:0046034	4.03116251387e-13	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	ATP metabolic process
REAC:R-HSA-1428517	4.07665697935e-13	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	The citric acid (TCA) cycle and respiratory electron transport
KEGG:04714	5.52373441715e-13	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	Thermogenesis
GO:0042776	6.67660436685e-13	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	proton motive force-driven mitochondrial ATP synthesis
GO:0009205	8.88662068937e-13	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	purine ribonucleoside triphosphate metabolic process
GO:0009144	1.00831991032e-12	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	purine nucleoside triphosphate metabolic process
GO:0009199	1.29252935397e-12	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	ribonucleoside triphosphate metabolic process
GO:0009141	1.96976843691e-12	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	nucleoside triphosphate metabolic process
GO:1904949	8.94538433473e-12	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	ATPase complex
GO:0098800	1.58814039976e-11	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	inner mitochondrial membrane protein complex
GO:0015078	2.41147971394e-11	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	proton transmembrane transporter activity
GO:0009152	3.11436444946e-11	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	purine ribonucleotide biosynthetic process
GO:0009260	5.50193634319e-11	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	ribonucleotide biosynthetic process
REAC:R-HSA-1852241	5.59136869344e-11	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	Organelle biogenesis and maintenance
GO:0046390	7.90090252653e-11	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	ribose phosphate biosynthetic process
GO:0006164	1.84918687416e-10	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	purine nucleotide biosynthetic process
GO:0072522	2.41713058643e-10	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	purine-containing compound biosynthetic process
GO:0006119	2.44605497247e-10	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	oxidative phosphorylation
GO:0009150	5.26627370085e-10	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	purine ribonucleotide metabolic process
GO:0009165	5.4388695946e-10	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	nucleotide biosynthetic process
GO:1901293	6.59457107636e-10	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	nucleoside phosphate biosynthetic process
GO:0009259	7.4426668009e-10	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	ribonucleotide metabolic process
GO:0019693	1.11127284115e-09	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	ribose phosphate metabolic process
KEGG:05415	1.14724008067e-09	0.444444444444	ATP5PO ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 MT-ATP6 ATP5PD	Diabetic cardiomyopathy
GO:0016874	1.34812874118e-09	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	ligase activity
GO:0009060	2.09650859531e-09	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	aerobic respiration
KEGG:05208	2.65061920147e-09	0.444444444444	ATP5PO ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 MT-ATP6 ATP5PD	Chemical carcinogenesis - reactive oxygen species
GO:0006163	4.42646015861e-09	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	purine nucleotide metabolic process
GO:0005216	5.78866387836e-09	0.555555555556	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 TMEM120A ATP5MG MT-ATP6 ATP5PD	monoatomic ion channel activity
GO:0045333	6.63471047207e-09	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	cellular respiration
GO:0072521	6.9506576475e-09	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	purine-containing compound metabolic process
KEGG:05012	9.83659686044e-09	0.444444444444	ATP5PO ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 MT-ATP6 ATP5PD	Parkinson disease
GO:0009117	1.2224733959e-08	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	nucleotide metabolic process
KEGG:05020	1.23929470008e-08	0.444444444444	ATP5PO ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 MT-ATP6 ATP5PD	Prion disease
GO:0098798	1.2957118422e-08	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	mitochondrial protein-containing complex
GO:0006753	1.42880528243e-08	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	nucleoside phosphate metabolic process
GO:0015267	1.65207576618e-08	0.555555555556	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 TMEM120A ATP5MG MT-ATP6 ATP5PD	channel activity
GO:0022803	1.70958697179e-08	0.555555555556	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 TMEM120A ATP5MG MT-ATP6 ATP5PD	passive transmembrane transporter activity
KEGG:05016	2.76369225476e-08	0.444444444444	ATP5PO ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 MT-ATP6 ATP5PD	Huntington disease
GO:0005261	3.07162111601e-08	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	monoatomic cation channel activity
GO:0055086	5.29096376845e-08	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	nucleobase-containing small molecule metabolic process
GO:0006091	6.71197791472e-08	0.555555555556	ATP5PO ATP5ME ATP5F1E ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	generation of precursor metabolites and energy
GO:0015980	8.23232578951e-08	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	energy derivation by oxidation of organic compounds
GO:0022857	8.26445346926e-08	0.666666666667	ATP5PO ATP5ME MT-ATP8 ATP5F1B SLC19A2 ATP5F1E ATP5PD TMEM120A ATP5MG ATP5F1C MT-ATP6 SLC43A3	transmembrane transporter activity
KEGG:05014	1.13587286478e-07	0.444444444444	ATP5PO ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 MT-ATP6 ATP5PD	Amyotrophic lateral sclerosis
WP:WP4932	1.41190114411e-07	0.333333333333	ATP5PO ATP5MC1 ATP5F1B ATP5F1E MT-ATP8 MT-ATP6	7q11 23 copy number variation syndrome
KEGG:05010	1.66069367881e-07	0.444444444444	ATP5PO ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 MT-ATP6 ATP5PD	Alzheimer disease
GO:0005215	3.14585855868e-07	0.666666666667	ATP5PO ATP5ME MT-ATP8 ATP5F1B SLC19A2 ATP5F1E ATP5PD TMEM120A ATP5MG ATP5F1C MT-ATP6 SLC43A3	transporter activity
GO:0005743	3.18697744027e-07	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	mitochondrial inner membrane
GO:0019866	5.59870302003e-07	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	organelle inner membrane
KEGG:05022	7.78005194967e-07	0.444444444444	ATP5PO ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 MT-ATP6 ATP5PD	Pathways of neurodegeneration - multiple diseases
GO:0090407	7.94806948756e-07	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	organophosphate biosynthetic process
GO:0015075	9.97010854722e-07	0.555555555556	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 TMEM120A ATP5MG MT-ATP6 ATP5PD	monoatomic ion transmembrane transporter activity
GO:0045261	1.20589885889e-06	0.222222222222	ATP5F1E ATP5PO ATP5F1C ATP5F1B	proton-transporting ATP synthase complex, catalytic core F(1)
KEGG:01100	2.68913812846e-06	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C CERS6 ATP5PD ATP5MG MT-ATP6 MT-ATP8	Metabolic pathways
GO:1901137	2.76150808201e-06	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	carbohydrate derivative biosynthetic process
GO:0022890	3.63168740171e-06	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	inorganic cation transmembrane transporter activity
GO:0000276	5.61890325943e-06	0.222222222222	ATP5PO ATP5MC1 ATP5PD ATP5MG	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO:0045263	5.61890325943e-06	0.222222222222	ATP5PO ATP5MC1 ATP5PD ATP5MG	proton-transporting ATP synthase complex, coupling factor F(o)
GO:0019637	5.81836947508e-06	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	organophosphate metabolic process
GO:0008324	7.70959721868e-06	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	monoatomic cation transmembrane transporter activity
GO:0031966	8.76137567289e-06	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	mitochondrial membrane
GO:1901135	1.20735703654e-05	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	carbohydrate derivative metabolic process
GO:0005740	1.65698290013e-05	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	mitochondrial envelope
GO:0015318	1.91693069257e-05	0.5	ATP5PO ATP5ME ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	inorganic molecular entity transmembrane transporter activity
REAC:R-HSA-1430728	2.76119113915e-05	0.666666666667	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B MT-ATP6 CERS6 ATP5PD ATP5MG ATP5F1C SLC19A2 MT-ATP8	Metabolism
GO:0033177	3.96119656039e-05	0.222222222222	ATP5PO ATP5MC1 ATP5PD ATP5MG	proton-transporting two-sector ATPase complex, proton-transporting domain
GO:0044281	7.09895066459e-05	0.666666666667	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B MT-ATP6 ATP5IF1 ATP5PD ATP5MG ATP5F1C SLC19A2 MT-ATP8	small molecule metabolic process
GO:1901566	0.000111288426101	0.666666666667	ATP5PO ATP5ME CERS6 ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5F1E ATP5MG MT-ATP6 MT-ATP8	organonitrogen compound biosynthetic process
GO:0033178	0.000189728495656	0.222222222222	ATP5F1E ATP5PO ATP5F1C ATP5F1B	proton-transporting two-sector ATPase complex, catalytic domain
GO:0000275	0.000783132248318	0.166666666667	ATP5F1E ATP5F1C ATP5F1B	mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
GO:0031967	0.00130825873275	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	organelle envelope
GO:0031975	0.00130825873275	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	envelope
GO:0098796	0.00132189239499	0.555555555556	ATP5PO ATP5ME ATP5MC1 ATP5F1B ATP5F1C ATP5F1E MT-ATP8 ATP5MG MT-ATP6 ATP5PD	membrane protein complex
GO:0005739	0.00200820437422	0.611111111111	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG MT-ATP6 MT-ATP8	mitochondrion
HP:0001987	0.00202723238706	0.222222222222	ATP5F1E MT-ATP8 ATP5F1B MT-ATP6	Hyperammonemia
GO:0006796	0.00381012690337	0.666666666667	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG P2RY1 MT-ATP6 MT-ATP8	phosphate-containing compound metabolic process
GO:0006793	0.00425042425191	0.666666666667	ATP5PO ATP5ME ATP5F1E ATP5MC1 ATP5F1B ATP5F1C ATP5IF1 ATP5PD ATP5MG P2RY1 MT-ATP6 MT-ATP8	phosphorus metabolic process
HP:0003535	0.00488652193353	0.166666666667	ATP5F1E MT-ATP6 MT-ATP8	3-Methylglutaconic aciduria
HP:0001258	0.00774053015037	0.222222222222	ZFYVE27 MT-ATP8 MT-ATP6 ATP5F1E	Spastic paraplegia
WP:000000	0.0143607129125	0.888888888889	MT-ATP6 ATP5PO ATP5ME CERS6 ATP5MC1 MT-ATP8 ATP5F1B ATP5F1C TMEM120A ATP5IF1 ATP5PD ATP5F1E ATP5MG P2RY1 SLC19A2 NTSR1	WIKIPATHWAYS
HP:0002445	0.0144799717245	0.166666666667	ATP5F1E MT-ATP6 MT-ATP8	Tetraplegia
HP:0010550	0.019046964037	0.222222222222	ZFYVE27 MT-ATP8 MT-ATP6 ATP5F1E	Paraplegia
HP:0003112	0.0337402986571	0.222222222222	ATP5F1E MT-ATP8 ATP5F1B MT-ATP6	Abnormal circulating amino acid concentration
HP:0002157	0.0346443948738	0.222222222222	ATP5F1E MT-ATP8 ATP5F1B MT-ATP6	Azotemia
HPA:0271111	0.0355839037277	0.222222222222	ATP5IF1 ATP5PD ATP5ME ATP5PO	kidney; bowman's capsule[>=Low]
HPA:0271123	0.0383993559826	0.222222222222	ATP5IF1 ATP5PD ATP5ME ATP5PO	kidney; collecting ducts[High]
HPA:0271143	0.0401640313613	0.222222222222	ATP5IF1 ATP5PD ATP5ME ATP5PO	kidney; proximal tubules (cell body)[High]
HP:0004364	0.0446941563776	0.222222222222	ATP5F1E MT-ATP8 ATP5F1B MT-ATP6	Abnormal circulating nitrogen compound concentration

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
ATP5F1D	ATP5PB	1.0	0.934
ATP5PO	ATP5ME	1.0	0.956
ATP5PB	ATP5ME	1.0	0.96
ATP5PF	ATP5PO	1.0	0.828
ATP5F1D	ATP5PO	1.0	0.922	structurally_consistent (P25705)
ATP5F1D	ATP5F1B	1.0	0.896	structurally_consistent (P36542)
ATP5F1D	ATP5ME	1.0	0.87
ATP5PD	ATP5PB	1.0	0.93	structurally_consistent (dimer)
ATP5F1D	ATP5F1C	1.0	0.9	structurally_consistent (dimer)
ATP5PB	ATP5MG	1.0	0.93	structurally_consistent (dimer)
ATP5F1C	ATP5F1B	1.0	0.972	structurally_consistent (dimer)
ATP5PD	ATP5F1D	1.0	0.926	structurally_consistent (P25705)
ATP5PB	ATP5PO	1.0	0.958	structurally_consistent (dimer)
ATP5PD	ATP5ME	1.0	0.916
ATP5F1D	ATP5MG	1.0	0.826
ATP5F1D	ATP5PF	1.0	0.82
ATP5PF	ATP5ME	1.0	0.902
ATP5F1D	ATP5F1E	1.0	0.88
ATP5PD	ATP5PO	1.0	0.96
ATP5PD	ATP5F1B	1.0	0.892
ATP5ME	ATP5MG	1.0	0.908
ATP5PO	ATP5F1B	1.0	0.964	structurally_consistent (dimer)
ATP5PB	ATP5PF	1.0	0.908	structurally_consistent (dimer)
ATP5F1B	ATP5MG	1.0	0.916
ATP5F1C	ATP5MG	1.0	0.964
ATP5PF	ATP5F1C	1.0	0.856
ATP5PO	ATP5F1C	1.0	0.974	structurally_consistent (P25705)
ATP5PB	ATP5F1B	1.0	0.938	structurally_consistent (P48047)
ATP5PB	MT-ATP6	1.0	0.826	structurally_consistent (dimer)
ATP5PD	ATP5PF	1.0	0.914
ATP5PF	ATP5F1B	0.999	0.832
ATP5PD	ATP5F1C	0.999	0.886	structurally_consistent (P00846)
ATP5PB	ATP5F1C	0.999	0.962	structurally_consistent (P00846)
ATP5ME	ATP5F1B	0.999	0.922
ATP5PF	MT-ATP6	0.999	0.938	structurally_consistent (P24539)
ATP5F1D	MT-ATP6	0.999	0.898
ATP5ME	ATP5F1C	0.999	0.754
ATP5PF	ATP5MG	0.999	0.922	structurally_consistent (P24539)
ATP5PD	ATP5MG	0.999	0.976	structurally_consistent (P24539)
ATP5PF	ATP5F1E	0.999	0.71
ZFYVE27	ATP5PB	0.999	0.09
ATP5PO	ATP5MG	0.999	0.972
MT-ATP8	ATP5PF	0.998	0.752
MT-ATP8	MT-ATP6	0.998	0.408
ATP5PB	MT-ATP8	0.998	0.728
ATP5ME	ATP5F1E	0.998	0.914
ZFYVE27	ATP5PO	0.998	0.178	structurally_consistent (P25705)
ATP5IF1	ATP5PO	0.997	0.488
MT-ATP6	ATP5F1B	0.997	0.816
ATP5PO	ATP5F1E	0.997	0.714
MT-ATP6	ATP5PO	0.997	0.834	structurally_consistent (P24539)
ATP5PF	ATP5IF1	0.997	0.472
MT-ATP8	ATP5PO	0.997	0.704
ATP5IF1	ATP5F1E	0.997	0.556
SLC43A3	ATP5F1B	0.996	0.172
ZFYVE27	ATP5PF	0.996	0.134
ATP5F1E	ATP5MG	0.996	0.802
ATP5PD	ATP5IF1	0.996	0.728	structurally_consistent (dimer)
MT-ATP6	ATP5ME	0.996	0.914
MT-ATP6	ATP5MG	0.995	0.858	structurally_consistent (P24539)
ATP5PD	ATP5F1E	0.995	0.728
ATP5F1D	ATP5IF1	0.995	0.424
ATP5F1C	ATP5F1E	0.994	0.762	structurally_consistent (dimer)
MT-ATP8	ATP5F1B	0.994	0.682
ZFYVE27	ATP5F1B	0.994	0.11
ATP5F1E	ATP5F1B	0.994	0.72
ATP5PD	MT-ATP6	0.994	0.84	structurally_consistent (dimer)
ATP5F1D	MT-ATP8	0.994	0.676
ATP5PO	P2RY1	0.993
ATP5PB	ATP5IF1	0.993	0.684
MT-ATP6	ATP5IF1	0.993	0.248	structurally_consistent (O75947)
MT-ATP6	ATP5F1C	0.993	0.872	structurally_consistent (dimer)
MT-ATP8	ATP5ME	0.992	0.654
MT-ATP8	ATP5F1C	0.992	0.67
ZFYVE27	ATP5F1C	0.992	0.092
ATP5PB	ATP5F1E	0.991	0.64
ATP5PB	SLC43A3	0.99	0.126
ATP5IF1	ATP5ME	0.99	0.256
SLC19A2	ATP5ME	0.989	0.112
ATP5PD	ZFYVE27	0.989	0.136
ATP5PF	CERS6	0.989	0.066
ATP5PB	CERS6	0.988	0.116
ZFYVE27	ATP5ME	0.988	0.096
P2RY1	CERS6	0.987
TMEM120A	ATP5F1B	0.986	0.12
MT-ATP8	CERS6	0.986	0.042
ATP5F1B	CERS6	0.985	0.104
ATP5PO	CERS6	0.985	0.062
MT-ATP8	ATP5IF1	0.984	0.114
ATP5PB	NTSR1	0.984
ATP5ME	CERS6	0.984	0.08
ATP5PB	SLC19A2	0.983	0.136	structurally_consistent (dimer)
ATP5PF	P2RY1	0.981
ATP5PD	SLC43A3	0.981	0.092
ATP5IF1	ATP5F1B	0.98	0.546
SLC19A2	ATP5F1B	0.978	0.136
ATP5PD	CERS6	0.978	0.132
SLC19A2	ATP5MG	0.977	0.124	structurally_consistent (P24539)
ATP5F1B	P2RY1	0.977
ATP5F1C	CERS6	0.976	0.09
ATP5F1D	CERS6	0.976	0.128
ATP5IF1	NTSR1	0.976
SLC19A2	TMEM120A	0.975	0.096
SLC43A3	ATP5PO	0.975	0.108
ATP5PF	TMEM120A	0.974	0.096
ATP5PF	SLC19A2	0.974	0.056	structurally_consistent (P24539)
ZFYVE27	ATP5MG	0.972	0.16
ATP5PB	TMEM120A	0.971	0.166
ZFYVE27	MT-ATP8	0.969	0.058
ATP5PB	ATP5MC1	0.966
ATP5PD	SLC19A2	0.965	0.094
SLC43A3	ATP5MG	0.965	0.054
MT-ATP8	ATP5F1E	0.964	0.296
ATP5IF1	SLC19A2	0.963	0.086
MT-ATP8	ATP5MG	0.963	0.676
MT-ATP8	SLC19A2	0.962	0.062
ATP5PD	MT-ATP8	0.961	0.632
NTSR1	ATP5F1C	0.96
ATP5PF	NTSR1	0.959
ZFYVE27	ATP5F1E	0.956	0.09
ATP5F1C	ATP5MC1	0.954
MT-ATP6	CERS6	0.954	0.148
TMEM120A	ATP5MC1	0.953
ATP5F1B	ATP5MC1	0.948
CERS6	ATP5MG	0.948	0.116
MT-ATP6	SLC19A2	0.947	0.072
ATP5PF	ATP5MC1	0.947
ATP5IF1	ATP5MG	0.938	0.502
ATP5ME	TMEM120A	0.938	0.048
ATP5PD	TMEM120A	0.937	0.06
ATP5F1E	CERS6	0.933	0.086
ATP5F1D	ZFYVE27	0.931	0.092
ATP5MC1	ATP5MG	0.931
SLC19A2	ATP5F1C	0.929	0.124
SLC43A3	ATP5ME	0.929	0.028
ATP5PO	SLC19A2	0.923	0.162	structurally_consistent (P24539)
ATP5ME	ATP5MC1	0.923
ATP5PD	ATP5MC1	0.922
ATP5F1D	SLC19A2	0.921	0.066
ATP5IF1	CERS6	0.919	0.068
ATP5PO	ATP5MC1	0.915
ATP5PD	P2RY1	0.914
SLC43A3	ATP5PF	0.91	0.082
SLC19A2	CERS6	0.906	0.084
TMEM120A	CERS6	0.901	0.08	structurally_consistent (Q9H5K3)
ZFYVE27	ATP5IF1	0.895	0.068
TMEM120A	ATP5F1E	0.895	0.07
ATP5MC1	CERS6	0.89
ZFYVE27	SLC19A2	0.88	0.112
ATP5IF1	ATP5F1C	0.878	0.438
ATP5PO	TMEM120A	0.874	0.112
NTSR1	CERS6	0.865
SLC43A3	ATP5F1C	0.86	0.058
ATP5PB	P2RY1	0.85		mutually_exclusive (O60779)
SLC19A2	ATP5MC1	0.849
ATP5F1C	P2RY1	0.843
SLC19A2	ATP5F1E	0.836	0.064
ATP5F1D	SLC43A3	0.828	0.106
ATP5ME	NTSR1	0.822
ATP5PD	NTSR1	0.817
MT-ATP6	ATP5F1E	0.816	0.864	structurally_consistent (P36542)
ATP5F1E	P2RY1	0.813
MT-ATP8	TMEM120A	0.81	0.066
ATP5F1D	TMEM120A	0.789	0.182
SLC43A3	TMEM120A	0.756	0.064
ATP5IF1	TMEM120A	0.752	0.05
TMEM120A	ATP5F1C	0.752	0.124
ATP5PO	NTSR1	0.728
P2RY1	ATP5MG	0.723
MT-ATP8	ATP5MC1	0.708
NTSR1	ATP5F1B	0.697
ATP5F1D	NTSR1	0.632
NTSR1	TMEM120A	0.619
NTSR1	ATP5MG	0.604
MT-ATP6	TMEM120A	0.592	0.08
SLC43A3	ATP5F1E	0.586	0.066
ATP5F1E	ATP5MC1	0.569
ATP5F1D	ATP5MC1	0.543
SLC19A2	P2RY1	0.442		structurally_consistent (dimer)
SLC43A3	CERS6	0.434	0.1
MT-ATP6	ATP5MC1	0.388
SLC43A3	ATP5IF1	0.386	0.058
SLC19A2	NTSR1	0.385
MT-ATP8	SLC43A3	0.372	0.04
SLC43A3	SLC19A2	0.362	0.05
SLC43A3	MT-ATP6	0.357	0.034
ATP5ME	P2RY1	0.356
SLC43A3	ATP5MC1	0.348
TMEM120A	ATP5MG	0.336	0.082
SLC43A3	NTSR1	0.298
ATP5IF1	ATP5MC1	0.278
NTSR1	ATP5MC1	0.25
MT-ATP6	NTSR1	0.243
NTSR1	ATP5F1E	0.18
MT-ATP8	NTSR1	0.16
ZFYVE27	TMEM120A	0.102	0.116
ZFYVE27	CERS6	0.094	0.184
ZFYVE27	MT-ATP6	0.076	0.102
ZFYVE27	SLC43A3	0.042	0.07
ZFYVE27	NTSR1	0.026
ATP5F1D	P2RY1	0.02

Related Complexes

Genename	Complexes
ATP5PD	huMAP3_00060.1 huMAP3_01732.1 huMAP3_05994.1 huMAP3_06247.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5F1D	huMAP3_00060.1 huMAP3_05738.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1 huMAP3_13050.1 huMAP3_13265.1
SLC43A3	huMAP3_00060.1 huMAP3_01732.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5PF	huMAP3_00060.1 huMAP3_05994.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
P2RY1	huMAP3_04595.1 huMAP3_08510.1 huMAP3_09775.1 huMAP3_10795.1
ZFYVE27	huMAP3_00060.1 huMAP3_01732.1 huMAP3_02673.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5PB	huMAP3_00060.1 huMAP3_01732.1 huMAP3_05994.1 huMAP3_06247.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5F1C	huMAP3_03298.1 huMAP3_05994.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
SLC19A2	huMAP3_00644.1 huMAP3_05994.1 huMAP3_09775.1 huMAP3_10274.1 huMAP3_11095.1
ATP5IF1	huMAP3_00060.1 huMAP3_00425.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1 huMAP3_13050.1
ATP5F1B	huMAP3_03963.1 huMAP3_05738.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
CERS6	huMAP3_05994.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
NTSR1	huMAP3_01732.1 huMAP3_05994.1 huMAP3_08393.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
MT-ATP6	huMAP3_00060.1 huMAP3_01732.1 huMAP3_05994.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5F1E	huMAP3_03298.1 huMAP3_03963.1 huMAP3_05738.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1 huMAP3_13050.1
MT-ATP8	huMAP3_00060.1 huMAP3_00114.1 huMAP3_07476.1 huMAP3_07490.1 huMAP3_07895.1 huMAP3_08716.1 huMAP3_09488.1 huMAP3_09775.1 huMAP3_11095.1
ATP5PO	huMAP3_00261.1 huMAP3_01649.1 huMAP3_03298.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08080.1 huMAP3_08510.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_10245.1 huMAP3_11095.1
ATP5ME	huMAP3_01731.1 huMAP3_03947.1 huMAP3_07476.1 huMAP3_07490.1 huMAP3_07895.1 huMAP3_08716.1 huMAP3_09488.1 huMAP3_09775.1 huMAP3_11095.1
ATP5MG	huMAP3_06247.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5MC1	huMAP3_04244.1 huMAP3_08393.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_10274.1 huMAP3_11095.1 huMAP3_13647.1
TMEM120A	huMAP3_01732.1 huMAP3_05994.1 huMAP3_08393.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1 huMAP3_13197.1 huMAP3_15312.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09775.1

Complex Portal: CPX-11627