hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09788.1

Complex Portal: CPX-18354

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
RGS12	Regulator of G-protein signaling 12 (RGS12)	5	UniProt NCBI
GNAT3	Guanine nucleotide-binding protein G(t) subunit alpha-3 (Gustducin alpha-3 chain)	5	UniProt NCBI
GNAI1	Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein)	5	UniProt NCBI
GNG7	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7	4	UniProt NCBI
GNG12	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12	5	UniProt NCBI
GNB4	Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4)	5	UniProt NCBI
RGS14	Regulator of G-protein signaling 14 (RGS14)	5	UniProt NCBI
GNAT2	Guanine nucleotide-binding protein G(t) subunit alpha-2 (Transducin alpha-2 chain)	5	UniProt NCBI
GNG11	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11	5	UniProt NCBI
GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (Transducin beta chain 3)	5	UniProt NCBI
GNAI3	Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)	5	UniProt NCBI
GNAO1	Guanine nucleotide-binding protein G(o) subunit alpha	5	UniProt NCBI
GNAQ	Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q)	5	UniProt NCBI
GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)	5	UniProt NCBI
OTUD3	OTU domain-containing protein 3 (EC 3.4.19.12)	5	UniProt NCBI
SMPDL3B	Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-)	5	UniProt NCBI
GNAI2	Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)	5	UniProt NCBI
GNG4	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4	5	UniProt NCBI
RIC8A	Synembryn-A (Protein Ric-8A)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0005834	2.30157855102e-28	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	heterotrimeric G-protein complex
GO:1905360	4.43246476901e-27	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	GTPase complex
REAC:R-HSA-392518	3.28091229426e-24	0.611111111111	GNAI3 GNAQ GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Signal amplification
GO:0031234	9.83535594044e-24	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	extrinsic component of cytoplasmic side of plasma membrane
REAC:R-HSA-392170	2.03263597148e-23	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	ADP signalling through P2Y purinoceptor 12
REAC:R-HSA-418594	1.61012802896e-21	0.777777777778	GNAT2 GNAI3 RGS12 GNG11 GNG4 GNAT3 GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 GNB1 GNAQ	G alpha (i) signalling events
GO:0019897	4.2070071519e-21	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	extrinsic component of plasma membrane
REAC:R-HSA-977444	1.01175308254e-20	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	GABA B receptor activation
REAC:R-HSA-991365	1.01175308254e-20	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Activation of GABAB receptors
REAC:R-HSA-418597	2.00464289425e-20	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	G alpha (z) signalling events
REAC:R-HSA-9660821	2.00464289425e-20	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	ADORA2B mediated anti-inflammatory cytokines production
REAC:R-HSA-9634597	2.77427519269e-20	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	GPER1 signaling
KEGG:04713	3.99687717975e-20	0.611111111111	GNAO1 GNG4 GNG7 GNAI2 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAQ	Circadian entrainment
WP:WP536	4.72723645131e-20	0.666666666667	GNAO1 GNG11 GNG4 GNG7 GNAI2 GNAI1 RGS14 GNB4 GNAI3 GNG12 GNB1 GNAQ	Calcium regulation in cardiac cells
REAC:R-HSA-977443	1.22055460986e-19	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	GABA receptor activation
KEGG:04724	1.35697927721e-19	0.611111111111	GNAO1 GNG4 GNG7 GNAI2 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAQ	Glutamatergic synapse
KEGG:04726	2.07613553974e-19	0.611111111111	GNAO1 GNG4 GNG7 GNAI2 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAQ	Serotonergic synapse
KEGG:04725	4.07300065104e-19	0.611111111111	GNAO1 GNG4 GNG7 GNAI2 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAQ	Cholinergic synapse
REAC:R-HSA-111885	4.5741037072e-19	0.611111111111	GNAI3 GNAQ GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Opioid Signalling
GO:0019898	1.46623598388e-18	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	extrinsic component of membrane
GO:0009898	1.46623598388e-18	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	cytoplasmic side of plasma membrane
GO:0007186	1.49240296803e-18	0.888888888889	GNAT2 GNAI3 GNAQ RGS12 GNG11 GNG4 GNAT3 GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 GNB1 RIC8A GNAO1	G protein-coupled receptor signaling pathway
KEGG:04728	4.24180727121e-18	0.611111111111	GNAO1 GNG4 GNG7 GNAI2 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAQ	Dopaminergic synapse
KEGG:04727	5.07940637047e-18	0.555555555556	GNAO1 GNG4 GNG7 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAI2	GABAergic synapse
KEGG:05032	5.9521907094e-18	0.555555555556	GNAO1 GNG4 GNG7 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAI2	Morphine addiction
REAC:R-HSA-9009391	1.15836243849e-17	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Extra-nuclear estrogen signaling
REAC:R-HSA-9664433	1.15836243849e-17	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Leishmania parasite growth and survival
REAC:R-HSA-9662851	1.15836243849e-17	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Anti-inflammatory response favouring Leishmania parasite infection
KEGG:04723	1.16034764847e-17	0.611111111111	GNAO1 GNG4 GNG7 GNAI2 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAQ	Retrograde endocannabinoid signaling
GO:0098562	2.30925499201e-17	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	cytoplasmic side of membrane
REAC:R-HSA-388396	2.67513679953e-17	0.777777777778	GNAT2 GNAI3 RGS12 GNG11 GNG4 GNAT3 GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 GNB1 GNAQ	GPCR downstream signalling
WP:WP35	5.15051560846e-17	0.555555555556	GNAO1 GNG4 GNG7 GNAI1 GNG11 GNAI2 GNG12 GNAI3 GNB1 GNAQ	G protein signaling pathways
REAC:R-HSA-400042	8.3101701566e-17	0.444444444444	GNG4 GNG7 GNAI1 GNG11 GNB4 GNG12 GNB1 GNAI2	Adrenaline,noradrenaline inhibits insulin secretion
REAC:R-HSA-372790	1.68320139215e-16	0.777777777778	GNAT2 GNAI3 RGS12 GNG11 GNG4 GNAT3 GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 GNB1 GNAQ	Signaling by GPCR
REAC:R-HSA-418555	7.65279424409e-16	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	G alpha (s) signalling events
KEGG:04926	7.77013228201e-16	0.555555555556	GNAO1 GNG4 GNG7 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAI2	Relaxin signaling pathway
KEGG:04371	1.03266931486e-15	0.555555555556	GNAQ GNG4 GNG7 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAI2	Apelin signaling pathway
KEGG:05163	2.60611681922e-15	0.611111111111	GNAO1 GNG4 GNG7 GNAI2 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAQ	Human cytomegalovirus infection
KEGG:05170	2.76240174606e-15	0.611111111111	GNAO1 GNG4 GNG7 GNAI2 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAQ	Human immunodeficiency virus 1 infection
REAC:R-HSA-422356	5.5603217922e-15	0.5	GNAQ GNG4 GNG7 GNAI1 GNG11 GNB4 GNB1 GNG12 GNAI2	Regulation of insulin secretion
KEGG:04062	1.05239815703e-14	0.555555555556	GNAQ GNG4 GNG7 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAI2	Chemokine signaling pathway
KEGG:05034	2.1457934762e-14	0.555555555556	GNAO1 GNG4 GNG7 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAI2	Alcoholism
REAC:R-HSA-9824443	4.41292705597e-14	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Parasitic Infection Pathways
REAC:R-HSA-9658195	4.41292705597e-14	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Leishmania infection
REAC:R-HSA-76002	5.37846980537e-14	0.611111111111	GNAI3 GNAQ GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Platelet activation, signaling and aggregation
REAC:R-HSA-202040	5.87778823734e-14	0.388888888889	GNAQ GNG4 GNG7 GNG11 GNB4 GNG12 GNB1	G-protein activation
REAC:R-HSA-418592	5.87778823734e-14	0.388888888889	GNAQ GNG4 GNG7 GNG11 GNB4 GNG12 GNB1	ADP signalling through P2Y purinoceptor 1
REAC:R-HSA-428930	5.87778823734e-14	0.388888888889	GNAQ GNG4 GNG7 GNG11 GNB4 GNG12 GNB1	Thromboxane signalling through TP receptor
REAC:R-HSA-163685	1.34369561189e-13	0.5	GNAQ GNG4 GNG7 GNAI1 GNG11 GNB4 GNB1 GNG12 GNAI2	Integration of energy metabolism
REAC:R-HSA-112314	2.05131141005e-13	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Neurotransmitter receptors and postsynaptic signal transmission
REAC:R-HSA-4086398	2.26024713097e-13	0.444444444444	GNAT2 GNAO1 GNG4 GNG7 GNG11 GNB4 GNB1 GNG12	Ca2+ pathway
REAC:R-HSA-456926	3.05051158074e-13	0.388888888889	GNAQ GNG4 GNG7 GNG11 GNB4 GNG12 GNB1	Thrombin signalling through proteinase activated receptors (PARs)
GO:0031683	3.60949030942e-13	0.388888888889	GNAT2 GNAQ GNAT3 GNAI1 GNAI2 GNAI3 GNAO1	G-protein beta/gamma-subunit complex binding
WP:WP3929	7.29421354015e-13	0.5	GNG4 GNG7 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAI2	Chemokine signaling pathway
REAC:R-HSA-8939211	1.02337380291e-12	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	ESR-mediated signaling
GO:0098552	1.71927762795e-12	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	side of membrane
GO:0098797	1.89374693603e-12	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	plasma membrane protein complex
REAC:R-HSA-6814122	2.29780758524e-12	0.388888888889	GNAQ GNG4 GNG7 GNG11 GNB4 GNG12 GNB1	Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
REAC:R-HSA-112315	2.62437929875e-12	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Transmission across Chemical Synapses
REAC:R-HSA-392851	3.36958611354e-12	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Prostacyclin signalling through prostacyclin receptor
REAC:R-HSA-8964315	3.36958611354e-12	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	G beta:gamma signalling through BTK
REAC:R-HSA-418217	5.20387405922e-12	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	G beta:gamma signalling through PLC beta
REAC:R-HSA-500657	5.20387405922e-12	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Presynaptic function of Kainate receptors
REAC:R-HSA-8964616	7.80031254159e-12	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	G beta:gamma signalling through CDC42
REAC:R-HSA-9006931	1.9012973015e-11	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Signaling by Nuclear Receptors
WP:WP4900	2.15680440021e-11	0.333333333333	GNAT2 GNAO1 GNAT3 GNAI1 GNAI2 GNAI3	Purinergic signaling
REAC:R-HSA-392451	2.27527591032e-11	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	G beta:gamma signalling through PI3Kgamma
GO:0003924	2.93753104585e-11	0.611111111111	GNAT2 GNAQ RGS12 GNG11 GNAT3 GNAI1 RGS14 GNAI2 GNB1 GNAI3 GNAO1	GTPase activity
REAC:R-HSA-451326	3.1263002061e-11	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Activation of kainate receptors upon glutamate binding
REAC:R-HSA-1296041	4.22672013205e-11	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Activation of G protein gated Potassium channels
REAC:R-HSA-420092	4.22672013205e-11	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Glucagon-type ligand receptors
REAC:R-HSA-997272	4.22672013205e-11	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
REAC:R-HSA-1296059	4.22672013205e-11	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	G protein gated Potassium channels
REAC:R-HSA-1296065	1.23592442252e-10	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Inwardly rectifying K+ channels
REAC:R-HSA-397795	1.23592442252e-10	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	G-protein beta:gamma signalling
REAC:R-HSA-163359	1.23592442252e-10	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Glucagon signaling in metabolic regulation
REAC:R-HSA-112316	1.24998963603e-10	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Neuronal System
WP:WP289	1.61073724137e-10	0.444444444444	GNAQ GNG11 GNG4 GNG7 RGS14 GNB4 GNB1 GNG12	Myometrial relaxation and contraction pathways
REAC:R-HSA-432040	5.58770321925e-10	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Vasopressin regulates renal water homeostasis via Aquaporins
REAC:R-HSA-3858494	5.7043527536e-10	0.444444444444	GNAT2 GNAO1 GNG4 GNG7 GNG11 GNB4 GNB1 GNG12	Beta-catenin independent WNT signaling
REAC:R-HSA-162582	6.22443160231e-10	0.888888888889	GNAT2 GNAI3 GNAQ RGS12 GNG11 GNG4 GNAT3 GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 OTUD3 GNB1 GNAO1	Signal Transduction
REAC:R-HSA-381676	6.73902566271e-10	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
REAC:R-HSA-445717	8.08112965784e-10	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Aquaporin-mediated transport
REAC:R-HSA-109582	9.06483909271e-10	0.611111111111	GNAI3 GNAQ GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Hemostasis
KEGG:05200	1.31110659516e-09	0.555555555556	GNAQ GNG4 GNG7 GNAI1 GNG11 GNB4 GNG12 GNAI3 GNB1 GNAI2	Pathways in cancer
REAC:R-HSA-390466	1.63178870941e-09	0.388888888889	GNAQ GNG4 GNG7 GNG11 GNB4 GNG12 GNB1	Chaperonin-mediated protein folding
GO:0017111	2.76327413696e-09	0.611111111111	GNAT2 GNAQ RGS12 GNG11 GNAT3 GNAI1 RGS14 GNAI2 GNB1 GNAI3 GNAO1	ribonucleoside triphosphate phosphatase activity
REAC:R-HSA-391251	2.88284883851e-09	0.388888888889	GNAQ GNG4 GNG7 GNG11 GNB4 GNG12 GNB1	Protein folding
WP:WP2032	4.54491237661e-09	0.333333333333	GNAQ GNAI1 GNAI2 GNB1 GNAI3 GNAO1	Thyroid stimulating hormone TSH signaling pathway
GO:0016818	9.89357440853e-09	0.611111111111	GNAT2 GNAQ RGS12 GNG11 GNAT3 GNAI1 RGS14 GNAI2 GNB1 GNAI3 GNAO1	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0016817	9.89357440853e-09	0.611111111111	GNAT2 GNAQ RGS12 GNG11 GNAT3 GNAI1 RGS14 GNAI2 GNB1 GNAI3 GNAO1	hydrolase activity, acting on acid anhydrides
GO:0016462	9.89357440853e-09	0.611111111111	GNAT2 GNAQ RGS12 GNG11 GNAT3 GNAI1 RGS14 GNAI2 GNB1 GNAI3 GNAO1	pyrophosphatase activity
WP:WP722	1.18118963696e-08	0.277777777778	GNAI3 GNAQ GNAI2 GNAI1 GNAO1	Serotonin HTR1 group and FOS pathway
REAC:R-HSA-416482	2.5041276404e-08	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	G alpha (12/13) signalling events
GO:0007188	3.56572138577e-08	0.444444444444	GNAT2 GNAQ GNAT3 GNAI1 GNAI2 GNB1 GNAI3 GNAO1	adenylate cyclase-modulating G protein-coupled receptor signaling pathway
REAC:R-HSA-416476	3.57878936039e-08	0.388888888889	GNAQ GNG4 GNG7 GNG11 GNB4 GNG12 GNB1	G alpha (q) signalling events
REAC:R-HSA-1296071	3.69063811566e-08	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Potassium Channels
REAC:R-HSA-373080	4.43966517901e-08	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Class B/2 (Secretin family receptors)
REAC:R-HSA-418346	6.31950909177e-08	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Platelet homeostasis
CORUM:7031	6.32531883213e-08	0.166666666667	GNB1 GNAI1 GNG4	GNAI1-GNB1-GNG4 complex
CORUM:7034	6.32531883213e-08	0.166666666667	GNG4 GNAI1 GNB4	GNAI1-GNB4-GNG4 complex
CORUM:7066	6.32531883213e-08	0.166666666667	GNG7 GNAI1 GNB1	GNAI1-GNB1-GNG7 complex
CORUM:7069	6.32531883213e-08	0.166666666667	GNG7 GNAI1 GNB4	GNAI1-GNB4-GNG7 complex
CORUM:7081	6.32531883213e-08	0.166666666667	GNG11 GNAI1 GNB1	GNAI1-GNB1-GNG11 complex
CORUM:7084	6.32531883213e-08	0.166666666667	GNG11 GNAI1 GNB4	GNAI1-GNB4-GNG11 complex
CORUM:7089	6.32531883213e-08	0.166666666667	GNG12 GNAI1 GNB4	GNAI1-GNB4-GNG12 complex
GO:0098796	7.4672776078e-08	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	membrane protein complex
REAC:R-HSA-170670	1.03894283295e-07	0.222222222222	GNAT3 GNAI2 GNAI1 GNAI3	Adenylate cyclase inhibitory pathway
KEGG:04730	1.50533246846e-07	0.277777777778	GNAI3 GNAQ GNAI2 GNAI1 GNAO1	Long-term depression
REAC:R-HSA-195721	2.99717999493e-07	0.444444444444	GNAT2 GNAO1 GNG4 GNG7 GNG11 GNB4 GNB1 GNG12	Signaling by WNT
GO:0007165	5.08082168322e-07	1.0	GNAT2 GNAI3 GNAQ RGS12 GNG11 GNG4 GNAT3 SMPDL3B GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 OTUD3 GNB1 RIC8A GNAO1	signal transduction
REAC:R-HSA-112040	7.08086336336e-07	0.277777777778	GNAT3 GNAQ GNAI2 GNAI1 GNAI3	G-protein mediated events
WP:WP4223	1.85657888443e-06	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Ras signaling
KEGG:04015	1.91303522524e-06	0.333333333333	GNAQ GNAI1 RGS14 GNAI2 GNAI3 GNAO1	Rap1 signaling pathway
KEGG:05167	2.05490440608e-06	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Kaposi sarcoma-associated herpesvirus infection
GO:0023052	2.12340042541e-06	1.0	GNAT2 GNAI3 GNAQ RGS12 GNG11 GNG4 GNAT3 SMPDL3B GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 OTUD3 GNB1 RIC8A GNAO1	signaling
KEGG:04916	2.48693153267e-06	0.277777777778	GNAI3 GNAQ GNAI2 GNAI1 GNAO1	Melanogenesis
GO:0007154	2.65007736894e-06	1.0	GNAT2 GNAI3 GNAQ RGS12 GNG11 GNG4 GNAT3 SMPDL3B GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 OTUD3 GNB1 RIC8A GNAO1	cell communication
WP:WP2355	2.98840399778e-06	0.277777777778	GNB1 GNAQ GNAI2 GNAI1 GNAO1	Corticotropin releasing hormone signaling pathway
KEGG:05142	3.34312652064e-06	0.277777777778	GNAI3 GNAQ GNAI2 GNAI1 GNAO1	Chagas disease
KEGG:04014	3.53472111784e-06	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Ras signaling pathway
KEGG:04915	4.18413768597e-06	0.277777777778	GNAI3 GNAQ GNAI2 GNAI1 GNAO1	Estrogen signaling pathway
REAC:R-HSA-5663205	4.33311940922e-06	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Infectious disease
GO:0005886	5.01639413227e-06	0.944444444444	GNAT2 GNAI3 GNAQ RGS12 GNG11 GNG4 GNAT3 SMPDL3B GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 GNB1 RIC8A GNAO1	plasma membrane
KEGG:04921	1.46010170159e-05	0.277777777778	GNAI3 GNAQ GNAI2 GNAI1 GNAO1	Oxytocin signaling pathway
KEGG:04924	1.78198319556e-05	0.222222222222	GNAI3 GNAI2 GNAI1 GNAQ	Renin secretion
GO:0071944	2.55736231073e-05	0.944444444444	GNAT2 GNAI3 GNAQ RGS12 GNG11 GNG4 GNAT3 SMPDL3B GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 GNB1 RIC8A GNAO1	cell periphery
KEGG:04971	2.67144648766e-05	0.222222222222	GNAI3 GNAI2 GNAI1 GNAQ	Gastric acid secretion
GO:0051716	3.65829585625e-05	1.0	GNAT2 GNAI3 GNAQ RGS12 GNG11 GNG4 GNAT3 SMPDL3B GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 OTUD3 GNB1 RIC8A GNAO1	cellular response to stimulus
WP:WP3932	4.1569342751e-05	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Focal adhesion PI3K Akt mTOR signaling pathway
GO:0016787	4.36361004094e-05	0.722222222222	GNAT2 GNAQ RGS12 GNG11 GNAT3 SMPDL3B GNAI1 RGS14 GNAI2 GNB1 GNAI3 OTUD3 GNAO1	hydrolase activity
GO:1902494	4.39950893436e-05	0.722222222222	GNAT2 GNAI3 GNAO1 GNG4 GNAT3 GNAI2 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAQ	catalytic complex
KEGG:04151	4.77484372754e-05	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	PI3K-Akt signaling pathway
CORUM:7033	5.77699275587e-05	0.111111111111	GNG4 GNAI1	GNAI1-GNB3-GNG4 complex
CORUM:7204	5.77699275587e-05	0.111111111111	GNG12 GNB1	GNAS-L-GNB1-GNG12 complex
CORUM:7086	5.77699275587e-05	0.111111111111	GNB1 GNAI1	GNAI1-GNB1-GNG12 complex
CORUM:7088	5.77699275587e-05	0.111111111111	GNG12 GNAI1	GNAI1-GNB3-GNG12 complex
CORUM:7207	5.77699275587e-05	0.111111111111	GNG12 GNB4	GNAS-L-GNB4-GNG12 complex
CORUM:7092	5.77699275587e-05	0.111111111111	GNB1 GNAI1	GNAI1-GNB1-GNG13 complex
CORUM:7095	5.77699275587e-05	0.111111111111	GNAI1 GNB4	GNAI1-GNB4-GNG13 complex
CORUM:7160	5.77699275587e-05	0.111111111111	GNB1 GNG4	GNAS-L-GNB1-GNG4 complex
CORUM:7163	5.77699275587e-05	0.111111111111	GNG4 GNB4	GNAS-L-GNB4-GNG4 complex
CORUM:7170	5.77699275587e-05	0.111111111111	GNG7 GNB1	GNAS-L-GNB1-GNG7 complex
CORUM:7173	5.77699275587e-05	0.111111111111	GNG7 GNB4	GNAS-L-GNB4-GNG7 complex
CORUM:7195	5.77699275587e-05	0.111111111111	GNG11 GNB1	GNAS-L-GNB1-GNG11 complex
CORUM:7202	5.77699275587e-05	0.111111111111	GNG11 GNB4	GNAS-L-GNB4-GNG11 complex
CORUM:7068	5.77699275587e-05	0.111111111111	GNG7 GNAI1	GNAI1-GNB3-GNG7 complex
CORUM:7083	5.77699275587e-05	0.111111111111	GNG11 GNAI1	GNAI1-GNB3-GNG11 complex
GO:0001664	6.5749692944e-05	0.388888888889	GNAT2 GNAQ GNAT3 GNAI1 GNAI2 GNAI3 GNAO1	G protein-coupled receptor binding
REAC:R-HSA-500792	6.7851669859e-05	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	GPCR ligand binding
WP:WP4172	6.99881299407e-05	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	PI3K Akt signaling pathway
KEGG:04540	8.74255347742e-05	0.222222222222	GNAI3 GNAI2 GNAI1 GNAQ	Gap junction
KEGG:04928	0.000163827673496	0.222222222222	GNAI3 GNAI2 GNAI1 GNAQ	Parathyroid hormone synthesis, secretion and action
CORUM:7024	0.000173183276299	0.111111111111	GNB1 GNAI1	GNAI1-GNB1-GNG3 complex
CORUM:7090	0.000173183276299	0.111111111111	GNG12 GNAI1	GNAI1-GNB5-GNG12 complex
CORUM:7082	0.000173183276299	0.111111111111	GNG11 GNAI1	GNAI1-GNB2-GNG11 complex
CORUM:7079	0.000173183276299	0.111111111111	GNAI1 GNB4	GNAI1-GNB4-GNG10 complex
CORUM:7076	0.000173183276299	0.111111111111	GNB1 GNAI1	GNAI1-GNB1-GNG10 complex
CORUM:7074	0.000173183276299	0.111111111111	GNAI1 GNB4	GNAI1-GNB4-GNG8 complex
CORUM:7071	0.000173183276299	0.111111111111	GNB1 GNAI1	GNAI1-GNB1-GNG8 complex
CORUM:7070	0.000173183276299	0.111111111111	GNG7 GNAI1	GNAI1-GNB5-GNG7 complex
CORUM:7067	0.000173183276299	0.111111111111	GNG7 GNAI1	GNAI1-GNB2-GNG7 complex
CORUM:7087	0.000173183276299	0.111111111111	GNG12 GNAI1	GNAI1-GNB2-GNG12 complex
CORUM:7060	0.000173183276299	0.111111111111	GNAI1 GNB4	GNAI1-GNB4-GNG5 complex
CORUM:7035	0.000173183276299	0.111111111111	GNG4 GNAI1	GNAI1- GNB5-GNG4 complex
CORUM:7032	0.000173183276299	0.111111111111	GNG4 GNAI1	GNAI1-GNB2-GNG4 complex
CORUM:7027	0.000173183276299	0.111111111111	GNAI1 GNB4	GNAI1-GNB4-GNG3 complex
CORUM:7022	0.000173183276299	0.111111111111	GNAI1 GNB4	GNAI1-GNB4-GNG2 complex
CORUM:7019	0.000173183276299	0.111111111111	GNB1 GNAI1	GNAI1-GNB1-GNG2 complex
CORUM:7017	0.000173183276299	0.111111111111	GNAI1 GNB4	GNAI1-GNB4-GNGT1 complex
CORUM:7014	0.000173183276299	0.111111111111	GNB1 GNAI1	GNAI1-GNGT1-GNB1 complex
CORUM:7036	0.000173183276299	0.111111111111	GNB1 GNAI1	GNAI1-GNB1-GNG5 complex
CORUM:7085	0.000173183276299	0.111111111111	GNG11 GNAI1	GNAI1-GNB5-GNG11 complex
GO:0031681	0.000189728495656	0.222222222222	GNG4 GNG7 GNG11 GNG12	G-protein beta-subunit binding
KEGG:05145	0.000236813895064	0.222222222222	GNAI3 GNAI2 GNAI1 GNAO1	Toxoplasmosis
KEGG:04611	0.000318351443846	0.222222222222	GNAI3 GNAI2 GNAI1 GNAQ	Platelet activation
WP:WP26	0.000323364335236	0.166666666667	GNAI3 GNAI1 GNAI2	S1P receptor signal transduction
KEGG:04935	0.00034504803403	0.222222222222	GNAI3 GNAI2 GNAI1 GNAQ	Growth hormone synthesis, secretion and action
CORUM:117	0.000346113734644	0.111111111111	GNB1 GNAQ	GPR56-CD81-Galpha(q/11)-Gbeta complex
CORUM:6806	0.000346113734644	0.111111111111	GNB1 GNAI2	IGF1R-CXCR4-GNAI2-GNB1 complex
KEGG:04071	0.000388153787251	0.222222222222	GNAI3 GNAI2 GNAI1 GNAQ	Sphingolipid signaling pathway
GO:0007212	0.000475649605248	0.222222222222	GNAI3 GNB1 GNAO1 GNAQ	dopamine receptor signaling pathway
WP:WP5380	0.000589204377699	0.222222222222	RGS14 GNAI2 GNAI1 GNAI3	5q35 copy number variation
GO:0050896	0.000609755714354	1.0	GNAT2 GNAI3 GNAQ RGS12 GNG11 GNG4 GNAT3 SMPDL3B GNAI2 GNAI1 RGS14 GNB4 GNG7 GNG12 OTUD3 GNB1 RIC8A GNAO1	response to stimulus
KEGG:04261	0.00068861320073	0.222222222222	GNAI3 GNAI2 GNAI1 GNAQ	Adrenergic signaling in cardiomyocytes
REAC:R-HSA-1643685	0.000715046307537	0.555555555556	GNAI3 GNG4 GNAT3 GNAI1 GNG11 GNB4 GNG7 GNG12 GNB1 GNAI2	Disease
KEGG:04022	0.000836556317546	0.222222222222	GNAI3 GNAI2 GNAI1 GNAQ	cGMP-PKG signaling pathway
KEGG:04934	0.000836556317546	0.222222222222	GNAI3 GNAI2 GNAI1 GNAQ	Cushing syndrome
KEGG:05030	0.000955280009043	0.166666666667	GNAI3 GNAI1 GNAI2	Cocaine addiction
KEGG:04923	0.00110421784374	0.166666666667	GNAI3 GNAI1 GNAI2	Regulation of lipolysis in adipocytes
GO:1903351	0.00187602769946	0.222222222222	GNAI3 GNB1 GNAO1 GNAQ	cellular response to dopamine
GO:1903350	0.00187602769946	0.222222222222	GNAI3 GNB1 GNAO1 GNAQ	response to dopamine
GO:0071870	0.00216298700857	0.222222222222	GNAI3 GNB1 GNAO1 GNAQ	cellular response to catecholamine stimulus
GO:0071867	0.00216298700857	0.222222222222	GNAI3 GNB1 GNAO1 GNAQ	response to monoamine
GO:0071869	0.00216298700857	0.222222222222	GNAI3 GNB1 GNAO1 GNAQ	response to catecholamine
GO:0071868	0.00216298700857	0.222222222222	GNAI3 GNB1 GNAO1 GNAQ	cellular response to monoamine stimulus
KEGG:05133	0.00287313003702	0.166666666667	GNAI3 GNAI1 GNAI2	Pertussis
WP:WP3679	0.00472105005501	0.111111111111	GNAI1 GNAQ	Cell type dependent selectivity of CCK2R signaling
GO:0001750	0.00715797050704	0.222222222222	GNAT3 GNB1 GNAQ GNAT2	photoreceptor outer segment
KEGG:04914	0.00768943375163	0.166666666667	GNAI3 GNAI1 GNAI2	Progesterone-mediated oocyte maturation
KEGG:04670	0.00885857524215	0.166666666667	GNAI3 GNAI1 GNAI2	Leukocyte transendothelial migration
REAC:R-HSA-382551	0.00901069798332	0.333333333333	GNG12 GNG7 GNG11 GNB4 GNB1 GNG4	Transport of small molecules
KEGG:04744	0.0113367334003	0.111111111111	GNAT2 GNB1	Phototransduction
WP:WP1602	0.0152763590598	0.111111111111	GNB1 GNAI1	Nicotine effect on dopaminergic neurons
WP:WP4540	0.0154515808248	0.166666666667	GNAI3 GNAQ GNAI2	Hippo signaling regulation pathways
REAC:R-HSA-392499	0.02224694533	0.5	GNAQ GNG4 GNAT3 GNG11 GNB4 GNG7 GNG12 GNB1 OTUD3	Metabolism of proteins
REAC:R-HSA-1430728	0.0298073698822	0.5	GNAQ GNG4 GNG7 GNAI1 GNG11 GNB4 GNB1 GNG12 GNAI2	Metabolism
GO:0097733	0.037611258724	0.222222222222	GNAT3 GNB1 GNAQ GNAT2	photoreceptor cell cilium
WP:WP5122	0.0385527194087	0.111111111111	GNAI1 GNAQ	Prostaglandin and leukotriene metabolism in senescence
KEGG:04360	0.0490310017589	0.166666666667	GNAI3 GNAI1 GNAI2	Axon guidance
CORUM:7206	0.0496617483143	0.0555555555556	GNG12	GNAS-L-GNB3-GNG12 complex
CORUM:7201	0.0496617483143	0.0555555555556	GNG11	GNAS-L-GNB3-GNG11 complex
CORUM:7172	0.0496617483143	0.0555555555556	GNG7	GNAS-L-GNB3-GNG7 complex
CORUM:7162	0.0496617483143	0.0555555555556	GNG4	GNAS-L-GNB3-GNG4 complex
CORUM:7094	0.0496617483143	0.0555555555556	GNAI1	GNAI1-GNB3-GNG13 complex
CORUM:7212	0.0496617483143	0.0555555555556	GNB4	GNAS-L-GNB4-GNG13 complex
CORUM:7209	0.0496617483143	0.0555555555556	GNB1	GNAS-L-GNB1-GNG13 complex
WP:WP5321	0.0499589979606	0.111111111111	GNAI1 GNAQ	Prostaglandin and leukotriene metabolism in senescence

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
GNAI3	RIC8A	1.0	0.06
GNAI1	GNAI3	0.999	0.57	structurally_consistent (dimer)
GNAI3	GNAI2	0.999	0.286
GNAO1	RIC8A	0.999	0.068
GNG7	GNB1	0.999	0.150619047619
GNAO1	GNAI2	0.999	0.082
GNAI3	GNAO1	0.999	0.106
GNAI2	RIC8A	0.999	0.042
OTUD3	GNAT3	0.998		structurally_consistent (dimer)
GNAI1	RIC8A	0.998	0.072	structurally_consistent (dimer)
RGS12	GNAI3	0.998	0.068
GNAI3	GNG12	0.997	0.086
GNG7	GNAI2	0.997	0.126	structurally_consistent (dimer)
GNAI2	GNB1	0.997	0.244
GNAI1	GNB4	0.997	0.696	structurally_consistent (dimer)
GNAI3	GNG7	0.997	0.13
GNAI1	GNG12	0.997	0.084
GNAI3	GNB1	0.997	0.23	structurally_consistent (P16520)
GNG12	GNAI2	0.997	0.056
GNAI1	GNAI2	0.996	0.87
GNAI3	GNAQ	0.996	0.14
GNAI3	GNG4	0.996	0.082
GNAI2	GNAQ	0.996	0.28
GNAI1	GNAO1	0.996	0.164
GNAI3	GNB4	0.995	0.488
GNB4	GNAI2	0.994	0.458	mutually_exclusive (O60262)
GNAI3	GNAT2	0.994		structurally_consistent (dimer)
GNG4	GNB1	0.994	0.154	structurally_consistent (P16520) structurally_consistent (dimer)
GNG12	GNB1	0.994	0.162	structurally_consistent (P16520) structurally_consistent (dimer)
GNB4	GNAQ	0.993	0.356	structurally_consistent (dimer)
GNAQ	GNB1	0.993	0.37	structurally_consistent (P16520)
GNAI2	GNB3	0.993	0.069
RGS14	GNAI1	0.993	0.102	structurally_consistent (dimer)
GNAI1	GNAT3	0.992
GNAI1	RGS12	0.991	0.16
GNAI1	GNAQ	0.99	0.31
GNG12	GNAQ	0.99	0.126
GNG4	GNG7	0.99	0.152
GNAI1	GNB1	0.989	0.762	structurally_consistent (P16520) structurally_consistent (dimer)
GNB4	GNG12	0.989	0.228	structurally_consistent (dimer)
GNG11	GNAI3	0.987	0.156	structurally_consistent (dimer)
GNAT2	GNAO1	0.986		structurally_consistent (dimer)
GNG4	GNAI2	0.983	0.076
GNG4	RIC8A	0.981	0.062
GNB4	GNB1	0.98	0.788
GNAQ	RIC8A	0.979	0.032
GNAO1	GNG4	0.979	0.288
GNAI1	GNG4	0.974	0.292
GNAI1	GNG11	0.974	0.238
RGS14	GNAI3	0.968	0.096	mutually_exclusive (P63096) structurally_consistent (dimer)
GNB4	GNG4	0.964	0.294	structurally_consistent (dimer)
SMPDL3B	GNAI3	0.964	0.108
GNAO1	GNB1	0.962	0.126
GNAO1	GNG7	0.956	0.098	structurally_consistent (dimer)
GNG4	GNG12	0.951	0.106
GNG7	RIC8A	0.942	0.06
RGS12	GNAT2	0.936
RIC8A	GNB1	0.929	0.068	mutually_exclusive (P63096)
GNAI1	GNG7	0.928	0.188
GNAT2	GNG4	0.921
RGS12	GNG4	0.899	0.114
GNAT2	GNG7	0.877		mutually_exclusive (P09471)
SMPDL3B	GNAQ	0.868	0.064	structurally_consistent (Q8IYP9)
GNAT2	RIC8A	0.854
GNG7	GNG12	0.844	0.184
RGS14	GNG11	0.825	0.092	mutually_exclusive (P08754)
GNB1	GNB3	0.818	0.328619047619	structurally_consistent (dimer)
RGS12	GNAO1	0.809	0.152
RGS12	GNG7	0.809	0.118
RGS12	RIC8A	0.803	0.09
SMPDL3B	GNAI2	0.778	0.09
GNAQ	GNB3	0.757	0.134	structurally_consistent (dimer)
GNAI1	GNB3	0.746	0.234	structurally_consistent (dimer)
GNAO1	GNAQ	0.715	0.126
GNAT3	GNB1	0.711
GNG12	RIC8A	0.709	0.044
GNG11	GNB1	0.704	0.306
SMPDL3B	GNAO1	0.681	0.092
OTUD3	GNG12	0.663	0.168
GNAI1	SMPDL3B	0.637	0.042
GNAI3	GNB3	0.63	0.186	structurally_consistent (dimer)
OTUD3	GNAI3	0.614	0.13
RGS12	GNAI2	0.596	0.124
GNB4	GNG7	0.595	0.146	structurally_consistent (dimer)
GNAI1	GNAT2	0.577		mutually_exclusive (P08754)
SMPDL3B	GNG12	0.563	0.116
RGS14	GNAT3	0.541		structurally_consistent (dimer)
GNG4	GNAQ	0.532	0.124
GNAI1	OTUD3	0.531	0.114
RIC8A	GNB3	0.518	0.084	mutually_exclusive (P63096)
RGS14	GNAT2	0.513		mutually_exclusive (P08754)
GNAT3	GNG11	0.513		structurally_consistent (Q9HAV0)
RGS14	RIC8A	0.476	0.068	mutually_exclusive (P63096)
RGS14	RGS12	0.476	0.08
GNAO1	GNB3	0.462	0.236
GNAT2	GNAI2	0.46
GNG11	GNAO1	0.445	0.09
GNAO1	GNB4	0.431	0.176	mutually_exclusive (O60262) structurally_consistent (dimer)
RGS12	GNB1	0.431	0.27
GNAT3	GNAI3	0.429
RGS14	GNB4	0.424	0.204
GNG11	GNG7	0.42	0.144
GNAT3	GNG12	0.415		structurally_consistent (Q9HAV0)
RGS14	GNB1	0.414	0.13
RGS14	GNAO1	0.411	0.088
RGS14	GNG7	0.4	0.108	mutually_exclusive (P04899)
GNG11	RIC8A	0.4	0.074
GNG11	GNG4	0.4	0.148
GNB4	RIC8A	0.389	0.106	mutually_exclusive (P63096)
GNG11	GNB4	0.388	0.294	structurally_consistent (dimer)
GNG11	GNAT2	0.378
RGS12	GNG11	0.367	0.114
RGS14	GNG4	0.367	0.154
RGS12	GNB4	0.337	0.13
OTUD3	GNAI2	0.329	0.118
GNG7	GNB3	0.329	0.152
OTUD3	GNB1	0.31	0.256
GNAO1	GNG12	0.286	0.088
RGS12	GNG12	0.283	0.078
GNG7	GNAQ	0.269	0.112
GNAT3	RIC8A	0.224
GNAT3	GNG4	0.224		structurally_consistent (Q9HAV0)
GNAT3	RGS12	0.224
GNAT3	GNG7	0.188		structurally_consistent (Q9HAV0)
GNAT2	GNB4	0.185
RGS14	GNAI2	0.18	0.048	structurally_consistent (dimer)
GNAT2	GNB1	0.168
GNAT2	GNG12	0.162
GNAT3	GNAO1	0.154		mutually_exclusive (Q9HAV0)
RGS14	GNG12	0.151	0.162
GNG12	GNB3	0.146	0.158	structurally_consistent (P62873) structurally_consistent (dimer)
GNG11	GNG12	0.143	0.124
GNAT3	GNAI2	0.134
GNAT2	GNAQ	0.13
SMPDL3B	GNB4	0.118	0.168
GNB4	GNB3	0.093	0.320571428571
GNAT3	GNB4	0.092		structurally_consistent (dimer)
GNG11	GNAI2	0.088	0.14
SMPDL3B	GNG7	0.087	0.104315789474
GNG4	GNB3	0.053	0.18	structurally_consistent (P62873) structurally_consistent (dimer)
SMPDL3B	GNG4	0.046	0.094
SMPDL3B	GNB1	0.033	0.1
OTUD3	SMPDL3B	0.016	0.12
GNAT3	SMPDL3B	0.013
SMPDL3B	GNB3	0.01	0.076
SMPDL3B	RIC8A	0.007	0.06

Related Complexes

Genename	Complexes
RGS12	huMAP3_01199.1 huMAP3_01486.1 huMAP3_03550.1 huMAP3_07033.1 huMAP3_07243.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1 huMAP3_15303.1
GNAT3	huMAP3_00585.1 huMAP3_02649.1 huMAP3_03009.1 huMAP3_07239.1 huMAP3_08287.1 huMAP3_08960.1 huMAP3_09788.1 huMAP3_10627.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1 huMAP3_13880.1 huMAP3_14724.1
GNAI1	huMAP3_00466.1 huMAP3_05502.1 huMAP3_05674.1 huMAP3_08718.1 huMAP3_09165.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1
GNG7	huMAP3_03550.1 huMAP3_05901.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNG12	huMAP3_03550.1 huMAP3_05674.1 huMAP3_07033.1 huMAP3_08591.1 huMAP3_08718.1 huMAP3_09165.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1
GNB4	huMAP3_03550.1 huMAP3_07033.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
RGS14	huMAP3_00466.1 huMAP3_01486.1 huMAP3_05502.1 huMAP3_07209.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12381.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNAT2	huMAP3_02643.1 huMAP3_08140.1 huMAP3_08591.1 huMAP3_08840.1 huMAP3_09214.1 huMAP3_09609.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNG11	huMAP3_01486.1 huMAP3_03550.1 huMAP3_07033.1 huMAP3_07209.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12381.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNB3	huMAP3_07745.1 huMAP3_08586.1 huMAP3_09174.1 huMAP3_09788.1 huMAP3_10180.1 huMAP3_10236.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12374.1 huMAP3_12474.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNAI3	huMAP3_01486.1 huMAP3_03550.1 huMAP3_07033.1 huMAP3_07209.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNAO1	huMAP3_02643.1 huMAP3_07033.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNAQ	huMAP3_05502.1 huMAP3_08591.1 huMAP3_08718.1 huMAP3_09165.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12658.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNB1	huMAP3_07033.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
OTUD3	huMAP3_00585.1 huMAP3_02649.1 huMAP3_03009.1 huMAP3_04266.1 huMAP3_08287.1 huMAP3_09788.1 huMAP3_10627.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1 huMAP3_13880.1 huMAP3_14724.1
SMPDL3B	huMAP3_01486.1 huMAP3_03550.1 huMAP3_07033.1 huMAP3_07209.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_12658.1 huMAP3_14897.1
GNAI2	huMAP3_05473.1 huMAP3_05901.1 huMAP3_08591.1 huMAP3_08713.1 huMAP3_09165.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1
GNG4	huMAP3_03550.1 huMAP3_07033.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
RIC8A	huMAP3_05901.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09788.1

Complex Portal: CPX-18354