hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09789.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MYH9 | Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) | 5 | UniProt NCBI |
| MYL3 | Myosin light chain 3 (Cardiac myosin light chain 1) (CMLC1) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular myosin alkali light chain) (Ventricular myosin light chain 1) (VLCl) (Ventricular/slow twitch myosin alkali light chain) (MLC-lV/sb) | 5 | UniProt NCBI |
| MYH10 | Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04814 | 3.63333755269e-05 | 1.0 | MYH9 MYH10 MYL3 | Motor proteins |
| GO:0016460 | 0.000170228592746 | 1.0 | MYH9 MYH10 MYL3 | myosin II complex |
| GO:0016459 | 0.000476755403739 | 1.0 | MYH9 MYH10 MYL3 | myosin complex |
| REAC:R-HSA-416572 | 0.0011650518872 | 0.666666666667 | MYH9 MYH10 | Sema4D induced cell migration and growth-cone collapse |
| REAC:R-HSA-5627117 | 0.0011650518872 | 0.666666666667 | MYH9 MYH10 | RHO GTPases Activate ROCKs |
| REAC:R-HSA-5625900 | 0.0011650518872 | 0.666666666667 | MYH9 MYH10 | RHO GTPases activate CIT |
| REAC:R-HSA-5627123 | 0.00129444299395 | 0.666666666667 | MYH9 MYH10 | RHO GTPases activate PAKs |
| REAC:R-HSA-400685 | 0.00172341693863 | 0.666666666667 | MYH9 MYH10 | Sema4D in semaphorin signaling |
| REAC:R-HSA-3928663 | 0.00221357222266 | 0.666666666667 | MYH9 MYH10 | EPHA-mediated growth cone collapse |
| KEGG:04270 | 0.00346604271076 | 0.666666666667 | MYH9 MYH10 | Vascular smooth muscle contraction |
| GO:0097513 | 0.00421361424067 | 0.666666666667 | MYH9 MYH10 | myosin II filament |
| KEGG:04530 | 0.00727572841175 | 0.666666666667 | MYH9 MYH10 | Tight junction |
| WP:WP51 | 0.00915401629696 | 0.666666666667 | MYL3 MYH10 | Regulation of actin cytoskeleton |
| KEGG:05130 | 0.0102516009655 | 0.666666666667 | MYH9 MYH10 | Pathogenic Escherichia coli infection |
| REAC:R-HSA-373755 | 0.0116360425406 | 0.666666666667 | MYH9 MYH10 | Semaphorin interactions |
| KEGG:04810 | 0.01431202154 | 0.666666666667 | MYH9 MYH10 | Regulation of actin cytoskeleton |
| REAC:R-HSA-5625740 | 0.0220121799777 | 0.666666666667 | MYH9 MYH10 | RHO GTPases activate PKNs |
| REAC:R-HSA-2682334 | 0.02256145142 | 0.666666666667 | MYH9 MYH10 | EPH-Ephrin signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MYH9 | MYL3 | 0.998 | 0.564 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MYL3 | MYH10 | 0.998 | 0.044 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MYH9 | MYH10 | 0.973 | 0.507 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM boldt_WMM treiber_WMM |
Related Complexes