List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_09807.1

Confidence: Moderate High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
CENPI	Centromere protein I (CENP-I) (FSH primary response protein 1) (Follicle-stimulating hormone primary response protein) (Interphase centromere complex protein 19) (Leucine-rich primary response protein 1)	5	UniProt   NCBI
CENPO	Centromere protein O (CENP-O) (Interphase centromere complex protein 36)	5	UniProt   NCBI
ITGB3BP	Centromere protein R (CENP-R) (Beta-3-endonexin) (Integrin beta-3-binding protein) (Nuclear receptor-interacting factor 3)	5	UniProt   NCBI
CENPK	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33)	5	UniProt   NCBI
CENPM	Centromere protein M (CENP-M) (Interphase centromere complex protein 39) (Proliferation-associated nuclear element protein 1)	5	UniProt   NCBI
CENPC	Centromere protein C (CENP-C) (Centromere autoantigen C) (Centromere protein C 1) (CENP-C 1) (Interphase centromere complex protein 7)	5	UniProt   NCBI
CENPT	Centromere protein T (CENP-T) (Interphase centromere complex protein 22)	5	UniProt   NCBI
CENPQ	Centromere protein Q (CENP-Q)	5	UniProt   NCBI
ZFX	Zinc finger X-chromosomal protein	5	UniProt   NCBI
CENPH	Centromere protein H (CENP-H) (Interphase centromere complex protein 35)	5	UniProt   NCBI
CENPP	Centromere protein P (CENP-P)	5	UniProt   NCBI
CENPN	Centromere protein N (CENP-N) (Interphase centromere complex protein 32)	5	UniProt   NCBI
CENPU	Centromere protein U (CENP-U) (Centromere protein of 50 kDa) (CENP-50) (Interphase centromere complex protein 24) (KSHV latent nuclear antigen-interacting protein 1) (MLF1-interacting protein) (Polo-box-interacting protein 1)	5	UniProt   NCBI
CENPX	Centromere protein X (CENP-X) (FANCM-associated histone fold protein 2) (FANCM-interacting histone fold protein 2) (Fanconi anemia-associated polypeptide of 10 kDa) (Retinoic acid-inducible gene D9 protein homolog) (Stimulated by retinoic acid gene 13 protein homolog)	5	UniProt   NCBI
CENPL	Centromere protein L (CENP-L) (Interphase centromere complex protein 33)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0000939	2.59466375679e-41	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	inner kinetochore
CORUM:1179	3.12785929312e-37	0.857142857143	CENPN CENPU CENPQ CENPT CENPP CENPO CENPL CENPH CENPM CENPK CENPC ITGB3BP	CENP-A NAC-CAD complex
CORUM:7394	1.1714110962e-34	0.785714285714	CENPU CENPN CENPH CENPQ CENPP CENPL CENPI CENPM CENPK CENPO ITGB3BP	CENP-H-I complex
REAC:R-HSA-774815	2.73469325035e-32	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	Nucleosome assembly
REAC:R-HSA-606279	2.73469325035e-32	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	Deposition of new CENPA-containing nucleosomes at the centromere
REAC:R-HSA-73886	1.88141464015e-27	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	Chromosome Maintenance
REAC:R-HSA-141424	3.9405046378e-26	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Amplification of signal from the kinetochores
REAC:R-HSA-141444	3.9405046378e-26	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
REAC:R-HSA-69618	3.63060726313e-25	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Mitotic Spindle Checkpoint
REAC:R-HSA-9648025	6.76666556719e-25	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	EML4 and NUDC in mitotic spindle formation
GO:0000776	1.02361206015e-24	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	kinetochore
GO:0000779	1.56268147876e-24	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	condensed chromosome, centromeric region
REAC:R-HSA-2500257	1.72862034795e-24	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Resolution of Sister Chromatid Cohesion
REAC:R-HSA-5663220	5.67072574321e-24	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	RHO GTPases Activate Formins
GO:0000775	1.90390051467e-22	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	chromosome, centromeric region
GO:0000793	3.39753489308e-22	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	condensed chromosome
REAC:R-HSA-2467813	5.05912687046e-22	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Separation of Sister Chromatids
REAC:R-HSA-68877	1.10268844817e-21	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Mitotic Prometaphase
REAC:R-HSA-68882	6.63605711581e-21	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Mitotic Anaphase
REAC:R-HSA-2555396	7.04445965098e-21	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Mitotic Metaphase and Anaphase
REAC:R-HSA-69620	1.30853928644e-19	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Cell Cycle Checkpoints
GO:0098687	2.09838826778e-19	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	chromosomal region
GO:0007059	2.5074383061e-19	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	chromosome segregation
REAC:R-HSA-195258	2.86700765296e-19	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	RHO GTPase Effectors
REAC:R-HSA-68886	9.90627644142e-18	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	M Phase
CORUM:927	1.15916483226e-17	0.428571428571	CENPU CENPN CENPH CENPM CENPC CENPT	CENP-A NAC complex
REAC:R-HSA-1640170	2.72407423308e-17	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	Cell Cycle
CORUM:929	5.4704178729e-17	0.571428571429	CENPU CENPH CENPK CENPL CENPI CENPM CENPO CENPC	CEN complex
REAC:R-HSA-69278	5.59893010681e-16	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Cell Cycle, Mitotic
REAC:R-HSA-194315	5.9501321591e-15	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Signaling by Rho GTPases
REAC:R-HSA-9716542	7.93227114398e-15	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Signaling by Rho GTPases, Miro GTPases and RHOBTB3
CORUM:7388	1.06805505012e-14	0.428571428571	CENPN CENPH CENPL CENPI CENPC CENPT	CENP-A nucleosomal complex
GO:0099080	3.28219628106e-13	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	supramolecular complex
GO:0022402	1.70271805607e-12	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	cell cycle process
GO:0007049	5.60747687962e-11	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	cell cycle
GO:0005694	2.50530059654e-10	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	chromosome
REAC:R-HSA-162582	2.28639725679e-08	0.928571428571	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPL CENPI CENPM CENPO CENPC ITGB3BP	Signal Transduction
GO:0005654	0.000158646533984	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	nucleoplasm
GO:0043228	0.000230814911387	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	non-membrane-bounded organelle
GO:0043232	0.000230814911387	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	intracellular non-membrane-bounded organelle
CORUM:6146	0.000266552996475	0.142857142857	CENPT CENPX	CENP-T-W-S-X heterotetramer complex
GO:0031981	0.000392018703376	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	nuclear lumen
GO:0070013	0.00798042960806	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	intracellular organelle lumen
GO:0043233	0.00798042960806	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	organelle lumen
GO:0031974	0.00798042960806	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	membrane-enclosed lumen
GO:0032991	0.00969883650892	1.0	CENPN CENPU CENPQ CENPT CENPH CENPK CENPP CENPX CENPL CENPI CENPM CENPO CENPC ITGB3BP	protein-containing complex
GO:0051383	0.0194497700986	0.214285714286	CENPH CENPC CENPT	kinetochore organization
GO:0034508	0.0460629135005	0.214285714286	CENPI CENPC CENPT	centromere complex assembly



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
CENPO	CENPP	1.0	0.376
CENPK	CENPH	1.0	0.43
ITGB3BP	CENPP	1.0	0.298
CENPU	ITGB3BP	1.0	0.25
CENPH	CENPI	1.0	0.328
CENPQ	CENPP	1.0	0.302
CENPU	CENPQ	1.0	0.524
CENPO	ITGB3BP	0.999	0.218
CENPU	CENPO	0.999	0.364
CENPU	CENPP	0.999	0.212
CENPO	CENPQ	0.999	0.462
ITGB3BP	CENPQ	0.999	0.302
CENPK	CENPI	0.999	0.206
CENPU	CENPI	0.999	0.268
ITGB3BP	CENPT	0.998	0.156
CENPU	CENPT	0.998	0.19
CENPP	CENPH	0.998	0.284
CENPH	CENPM	0.998	0.26
CENPN	ITGB3BP	0.998	0.21
CENPQ	CENPI	0.998	0.316
CENPC	CENPI	0.998	0.192
CENPN	CENPQ	0.998	0.286
CENPN	CENPI	0.998	0.238
CENPO	CENPT	0.997	0.36
CENPO	CENPI	0.996	0.256
CENPT	CENPQ	0.996	0.172
CENPI	CENPM	0.996	0.138
CENPN	CENPU	0.996	0.322
CENPN	CENPO	0.996	0.38
CENPC	CENPN	0.996	0.224
CENPU	CENPH	0.996	0.194
CENPC	CENPU	0.996	0.21
CENPT	CENPH	0.995	0.26
CENPU	CENPX	0.995	0.168
ITGB3BP	CENPH	0.995	0.196
CENPC	CENPQ	0.995	0.134
CENPQ	CENPX	0.994	0.124
CENPO	CENPX	0.994	0.156
CENPC	CENPO	0.994	0.182
CENPN	CENPT	0.993	0.218
ITGB3BP	CENPX	0.993	0.106
CENPK	CENPM	0.993	0.22
CENPC	CENPT	0.993	0.15
CENPO	CENPH	0.993	0.172
ITGB3BP	CENPI	0.993	0.206
CENPQ	CENPH	0.992	0.424
CENPP	CENPX	0.991	0.152
CENPT	CENPI	0.99	0.168
CENPP	CENPI	0.99	0.156
CENPN	CENPH	0.989	0.228
CENPL	CENPQ	0.988	0.176
CENPN	CENPP	0.985	0.258
CENPT	CENPP	0.984	0.138
ZFX	CENPU	0.983	0.138
CENPC	CENPP	0.982	0.152
CENPC	ITGB3BP	0.981	0.09
ZFX	CENPI	0.973	0.108
CENPL	CENPI	0.966	0.218
CENPC	CENPH	0.965	0.058
ITGB3BP	CENPK	0.965	0.194
CENPC	CENPL	0.964	0.242
CENPO	CENPK	0.962	0.264
CENPU	CENPK	0.962	0.228
CENPN	CENPL	0.961	0.276
CENPQ	CENPK	0.96	0.352
CENPQ	CENPM	0.959	0.17
CENPU	CENPL	0.956	0.216
CENPO	CENPM	0.953	0.184
CENPC	CENPK	0.946	0.154
CENPC	ZFX	0.94	0.098
CENPL	CENPO	0.938	0.308
CENPL	ITGB3BP	0.931	0.22
ZFX	CENPO	0.925	0.118
CENPU	CENPM	0.915	0.266
ZFX	CENPN	0.898	0.1
CENPX	CENPH	0.886	0.212
ZFX	ITGB3BP	0.852	0.118
ZFX	CENPQ	0.845	0.098
CENPC	CENPX	0.796	0.064
CENPC	CENPM	0.796	0.114
ITGB3BP	CENPM	0.785	0.226
CENPT	CENPK	0.785	0.166
CENPP	CENPK	0.785	0.22
CENPN	CENPK	0.785	0.224
CENPT	CENPM	0.785	0.136
CENPP	CENPM	0.785	0.172
CENPN	CENPM	0.785	0.136
CENPL	CENPH	0.765	0.252
CENPX	CENPM	0.764	0.148
CENPT	CENPX	0.764	0.166
CENPX	CENPK	0.764	0.226
CENPX	CENPI	0.764	0.124
CENPN	CENPX	0.764	0.134
ZFX	CENPT	0.232	0.104
ZFX	CENPK	0.232	0.118
ZFX	CENPM	0.232	0.062
ZFX	CENPH	0.232	0.112
ZFX	CENPP	0.232	0.112
ZFX	CENPX	0.232	0.062
CENPL	CENPX	0.192	0.134
CENPL	CENPT	0.192	0.16
CENPL	CENPK	0.192	0.182
CENPL	CENPP	0.192	0.294
CENPL	CENPM	0.192	0.148
ZFX	CENPL	0.135	0.09





Related Complexes

Genename	Complexes
CENPI	huMAP3_04427.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11265.1 huMAP3_11899.1 huMAP3_14808.1
CENPO	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
ITGB3BP	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPK	huMAP3_04427.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPM	huMAP3_09807.1 huMAP3_11899.1 huMAP3_12305.1 huMAP3_13642.1 huMAP3_14808.1
CENPC	huMAP3_01056.1 huMAP3_06427.1 huMAP3_09807.1
CENPT	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPQ	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
ZFX	huMAP3_01056.1 huMAP3_02155.1 huMAP3_04594.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11265.1 huMAP3_11899.1 huMAP3_14808.1
CENPH	huMAP3_04427.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_13975.1 huMAP3_14808.1
CENPP	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPN	huMAP3_01056.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPU	huMAP3_01056.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPX	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09167.1 huMAP3_09780.1 huMAP3_09807.1 huMAP3_09816.1 huMAP3_11696.1 huMAP3_11899.1 huMAP3_12695.1 huMAP3_13031.1 huMAP3_14509.1 huMAP3_14808.1
CENPL	huMAP3_01056.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1