hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09827.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GP1BB | Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (Antigen CD42b-beta) (CD antigen CD42c) | 5 | UniProt NCBI |
| ATP7B | Copper-transporting ATPase 2 (EC 7.2.2.8) (Copper pump 2) (Wilson disease-associated protein) [Cleaved into: WND/140 kDa] | 5 | UniProt NCBI |
| TMEM223 | Transmembrane protein 223 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5189 | 0.0248784837172 | 0.5 | ATP7B | Copper metabolism |
| HP:0010839 | 0.0499436884913 | 0.5 | ATP7B | Increased urinary copper concentration |
| HP:0025640 | 0.0499436884913 | 0.5 | ATP7B | Abnormal urinary mineral level |
| HP:0032254 | 0.0499436884913 | 0.5 | ATP7B | Increased circulating copper concentration |
| HP:0034254 | 0.0499436884913 | 0.5 | ATP7B | Face of the giant panda sign |
| HP:0045036 | 0.0499436884913 | 0.5 | ATP7B | Abnormal urinary copper concentration |
| HP:0200032 | 0.0499436884913 | 0.5 | ATP7B | Kayser-Fleischer ring |
| HP:0200122 | 0.0499436884913 | 0.5 | ATP7B | Atypical or prolonged hepatitis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ATP7B | TMEM223 | 0.968 | 0.116 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| TMEM223 | GP1BB | 0.954 | bioplex_WMM bioplex3_WMM WMM_only | |
| ATP7B | GP1BB | 0.231 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| GP1BB | huMAP3_07527.1 huMAP3_07796.1 huMAP3_09216.1 huMAP3_09827.1 huMAP3_11420.1 huMAP3_14700.1 huMAP3_15126.1 |
| ATP7B | huMAP3_00530.1 huMAP3_04522.1 huMAP3_08511.1 huMAP3_09827.1 |
| TMEM223 | huMAP3_00530.1 huMAP3_09827.1 |