List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_09833.1

Confidence: Moderate High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
PPL	Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)	5	UniProt   NCBI
FCGBP	IgGFc-binding protein (Fcgamma-binding protein antigen) (FcgammaBP)	5	UniProt   NCBI
GGCT	Gamma-glutamylcyclotransferase (EC 4.3.2.9) (Cytochrome c-releasing factor 21)	5	UniProt   NCBI
TYMP	Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase)	5	UniProt   NCBI
TRIM29	Tripartite motif-containing protein 29 (Ataxia telangiectasia group D-associated protein)	5	UniProt   NCBI
CRABP2	Cellular retinoic acid-binding protein 2 (Cellular retinoic acid-binding protein II) (CRABP-II)	5	UniProt   NCBI
TREX2	Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2)	5	UniProt   NCBI
NDRG2	Protein NDRG2 (N-myc downstream-regulated gene 2 protein) (Protein Syld709613)	5	UniProt   NCBI
ANXA8	Annexin A8 (Annexin VIII) (Annexin-8) (Vascular anticoagulant-beta) (VAC-beta)	5	UniProt   NCBI
EVPL	Envoplakin (210 kDa cornified envelope precursor protein) (210 kDa paraneoplastic pemphigus antigen) (p210)	5	UniProt   NCBI
SULT2B1	Sulfotransferase 2B1 (EC 2.8.2.2) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2) (Sulfotransferase family 2B member 1) (Sulfotransferase family cytosolic 2B member 1) (ST2B1)	5	UniProt   NCBI
STAT3	Signal transducer and activator of transcription 3 (Acute-phase response factor)	5	UniProt   NCBI
SERPINB7	Serpin B7 (Megsin) (TP55)	4	UniProt   NCBI
SERPINB5	Serpin B5 (Maspin) (Peptidase inhibitor 5) (PI-5)	5	UniProt   NCBI
EPPK1	Epiplakin (450 kDa epidermal antigen)	5	UniProt   NCBI
HMOX1	Heme oxygenase 1 (HO-1) (EC 1.14.14.18) [Cleaved into: Heme oxygenase 1 soluble form]	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HPA:0460181	8.13028295805e-05	0.538461538462	SERPINB5 SULT2B1 NDRG2 TRIM29 STAT3 EVPL PPL	skin 1; cells in granular layer[>=Low]
HPA:0470181	8.29680884488e-05	0.538461538462	SERPINB5 SULT2B1 TRIM29 STAT3 HMOX1 EVPL PPL	skin 2; cells in granular layer[>=Low]
HPA:0470182	0.000421825792523	0.461538461538	SERPINB5 SULT2B1 STAT3 HMOX1 EVPL TRIM29	skin 2; cells in granular layer[>=Medium]
HPA:0461411	0.00279160736905	0.461538461538	SERPINB5 NDRG2 TRIM29 STAT3 EVPL PPL	skin 1; cells in spinous layer[>=Low]
WP:WP4495	0.00382429600169	0.153846153846	HMOX1 STAT3	IL 10 anti inflammatory signaling pathway
HPA:0471411	0.00565844490003	0.461538461538	SERPINB5 SULT2B1 TRIM29 STAT3 EVPL PPL	skin 2; cells in spinous layer[>=Low]
HPA:0460183	0.00590023651791	0.307692307692	EVPL SERPINB5 TRIM29 SULT2B1	skin 1; cells in granular layer[High]
HPA:0470183	0.0060003146311	0.307692307692	SERPINB5 TRIM29 HMOX1 SULT2B1	skin 2; cells in granular layer[High]
HPA:0461391	0.00626857633823	0.461538461538	SERPINB5 NDRG2 TRIM29 STAT3 EVPL FCGBP	skin 1; cells in basal layer[>=Low]
HP:0025080	0.00759681327472	0.153846153846	SERPINB7 SULT2B1	Orthokeratotic hyperkeratosis
HPA:0460182	0.00863222480125	0.384615384615	EVPL SERPINB5 SULT2B1 TRIM29 NDRG2	skin 1; cells in granular layer[>=Medium]
HPA:0471391	0.0100477586633	0.461538461538	SERPINB5 NDRG2 TRIM29 STAT3 EVPL FCGBP	skin 2; cells in basal layer[>=Low]
KEGG:05206	0.0154550895581	0.230769230769	SERPINB5 STAT3 HMOX1	MicroRNAs in cancer
HPA:0471412	0.0230457136829	0.384615384615	EVPL SERPINB5 TRIM29 STAT3 SULT2B1	skin 2; cells in spinous layer[>=Medium]
HPA:0461451	0.0275084162837	0.307692307692	SULT2B1 PPL STAT3 NDRG2	skin 1; hair follicles[>=Low]
HPA:0461461	0.0312616678235	0.384615384615	STAT3 SERPINB5 FCGBP NDRG2 TRIM29	skin 1; langerhans cells[>=Low]
HPA:0470000	0.0429887673183	0.923076923077	FCGBP SULT2B1 SERPINB5 NDRG2 HMOX1 PPL SERPINB7 STAT3 EPPK1 EVPL GGCT TRIM29	skin 2
HPA:0471461	0.0460098554785	0.384615384615	STAT3 SERPINB5 FCGBP NDRG2 TRIM29	skin 2; langerhans cells[>=Low]
HPA:0461482	0.0470754202993	0.230769230769	NDRG2 STAT3 SULT2B1	skin 1; sebaceous glands[>=Medium]
CORUM:1522	0.0499717467432	0.0769230769231	STAT3	STAT3 homodimer complex
CORUM:7316	0.0499717467432	0.0769230769231	STAT3	NFKB1-STAT3 complex



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
CRABP2	EVPL	0.995	0.168
PPL	EVPL	0.992	0.462
TREX2	TRIM29	0.992
HMOX1	EVPL	0.99	0.116
TREX2	SERPINB5	0.989
TREX2	EVPL	0.989
TREX2	HMOX1	0.988
TREX2	PPL	0.987
PPL	TRIM29	0.986	0.232
TYMP	PPL	0.986	0.13
TYMP	EVPL	0.985	0.048
EVPL	TRIM29	0.985	0.232
SERPINB5	PPL	0.983	0.2
STAT3	EVPL	0.983
NDRG2	STAT3	0.982
HMOX1	TRIM29	0.982	0.148363636364
CRABP2	PPL	0.981	0.212
TREX2	CRABP2	0.981
PPL	HMOX1	0.981	0.168
STAT3	SULT2B1	0.98
EVPL	SULT2B1	0.98	0.2
HMOX1	SULT2B1	0.98	0.164
EPPK1	HMOX1	0.978	0.158
TYMP	SERPINB5	0.977	0.118
TREX2	SULT2B1	0.977
STAT3	TRIM29	0.977
TREX2	ANXA8	0.976
PPL	STAT3	0.976
TYMP	STAT3	0.976
TYMP	SERPINB7	0.975	0.082
EVPL	FCGBP	0.975
FCGBP	ANXA8	0.975
CRABP2	SULT2B1	0.973	0.084
FCGBP	SULT2B1	0.973
TYMP	FCGBP	0.973	0.068
CRABP2	FCGBP	0.973	0.018
NDRG2	ANXA8	0.973
TREX2	SERPINB7	0.972
STAT3	SERPINB7	0.972
FCGBP	TRIM29	0.97
NDRG2	FCGBP	0.969
TREX2	STAT3	0.969
NDRG2	SERPINB7	0.969
TYMP	HMOX1	0.968	0.118
PPL	SULT2B1	0.967	0.148
EPPK1	SERPINB5	0.967	0.16
PPL	FCGBP	0.966
CRABP2	STAT3	0.966
TREX2	EPPK1	0.965
TRIM29	ANXA8	0.964	0.264
NDRG2	TREX2	0.964
SERPINB5	TRIM29	0.964	0.408
NDRG2	EPPK1	0.963
STAT3	HMOX1	0.963
FCGBP	SERPINB7	0.962
SERPINB5	EVPL	0.962	0.196
SERPINB7	ANXA8	0.961	0.092
NDRG2	HMOX1	0.96
EPPK1	EVPL	0.959	0.086
HMOX1	ANXA8	0.957	0.156
CRABP2	TRIM29	0.954	0.228
TREX2	GGCT	0.954
SERPINB5	FCGBP	0.954
TYMP	TREX2	0.953
NDRG2	CRABP2	0.953
CRABP2	ANXA8	0.952	0.18
NDRG2	SERPINB5	0.951
EPPK1	FCGBP	0.951	0.076
GGCT	EVPL	0.951	0.052
NDRG2	SULT2B1	0.951
TYMP	CRABP2	0.951	0.034
EPPK1	ANXA8	0.948	0.206
NDRG2	TRIM29	0.948
TYMP	ANXA8	0.946	0.18
HMOX1	SERPINB7	0.946	0.245052631579
TYMP	EPPK1	0.945	0.18
NDRG2	PPL	0.945
NDRG2	EVPL	0.945
PPL	ANXA8	0.945	0.22
HMOX1	FCGBP	0.944	0.012
TYMP	TRIM29	0.942	0.224
TRIM29	SULT2B1	0.94	0.14
EPPK1	CRABP2	0.939	0.206
TYMP	NDRG2	0.938
TREX2	FCGBP	0.937
SERPINB5	SERPINB7	0.937	0.07
EPPK1	TRIM29	0.937	0.174
SERPINB5	HMOX1	0.934	0.186
EPPK1	PPL	0.932	0.202
CRABP2	SERPINB7	0.932	0.086
PPL	SERPINB7	0.931	0.102
TYMP	SULT2B1	0.931	0.084
EVPL	SERPINB7	0.931	0.086
SULT2B1	SERPINB7	0.927
SULT2B1	ANXA8	0.926	0.074
EVPL	ANXA8	0.922	0.216
EPPK1	SERPINB7	0.914	0.04
SERPINB5	SULT2B1	0.907	0.178
CRABP2	HMOX1	0.901	0.09
SERPINB5	ANXA8	0.899	0.492
TRIM29	SERPINB7	0.895	0.07
STAT3	ANXA8	0.89
EPPK1	SULT2B1	0.879	0.112
SERPINB5	CRABP2	0.871	0.324
SERPINB5	STAT3	0.79
GGCT	FCGBP	0.724	0.01
STAT3	FCGBP	0.722
NDRG2	GGCT	0.631
EPPK1	STAT3	0.627
GGCT	HMOX1	0.377	0.074
GGCT	SULT2B1	0.286	0.052
GGCT	SERPINB7	0.249	0.078
GGCT	PPL	0.244	0.036
GGCT	ANXA8	0.223	0.072
GGCT	SERPINB5	0.171	0.128
TYMP	GGCT	0.147	0.074
GGCT	TRIM29	0.144	0.124
GGCT	STAT3	0.084
GGCT	CRABP2	0.064	0.084
GGCT	EPPK1	0.038	0.046





Related Complexes

Genename	Complexes
PPL	huMAP3_03608.1 huMAP3_06046.1 huMAP3_06323.1 huMAP3_07646.1 huMAP3_07972.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
FCGBP	huMAP3_06323.1 huMAP3_07255.1 huMAP3_07761.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
GGCT	huMAP3_01434.1 huMAP3_02738.1 huMAP3_04424.1 huMAP3_04732.1 huMAP3_05804.1 huMAP3_06323.1 huMAP3_07255.1 huMAP3_07646.1 huMAP3_08429.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
TYMP	huMAP3_00406.1 huMAP3_05900.1 huMAP3_06323.1 huMAP3_07646.1 huMAP3_08527.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
TRIM29	huMAP3_06323.1 huMAP3_07646.1 huMAP3_09833.1 huMAP3_10678.1
CRABP2	huMAP3_03608.1 huMAP3_05900.1 huMAP3_06323.1 huMAP3_07761.1 huMAP3_08527.1 huMAP3_09833.1 huMAP3_09848.1 huMAP3_09929.1 huMAP3_10678.1
TREX2	huMAP3_01434.1 huMAP3_03864.1 huMAP3_04424.1 huMAP3_05804.1 huMAP3_06323.1 huMAP3_07255.1 huMAP3_07761.1 huMAP3_08429.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1 huMAP3_13525.1
NDRG2	huMAP3_01043.1 huMAP3_06637.1 huMAP3_08328.1 huMAP3_09833.1 huMAP3_10678.1
ANXA8	huMAP3_06637.1 huMAP3_08328.1 huMAP3_09833.1 huMAP3_10506.1 huMAP3_10678.1
EVPL	huMAP3_04732.1 huMAP3_06323.1 huMAP3_07255.1 huMAP3_07646.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
SULT2B1	huMAP3_06323.1 huMAP3_07646.1 huMAP3_09833.1 huMAP3_10678.1
STAT3	huMAP3_03864.1 huMAP3_06323.1 huMAP3_07761.1 huMAP3_09833.1 huMAP3_10678.1 huMAP3_12153.1
SERPINB7	huMAP3_06637.1 huMAP3_07701.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
SERPINB5	huMAP3_03608.1 huMAP3_03864.1 huMAP3_06323.1 huMAP3_07255.1 huMAP3_07761.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1 huMAP3_11636.1
EPPK1	huMAP3_03348.1 huMAP3_06046.1 huMAP3_06323.1 huMAP3_07646.1 huMAP3_09473.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1 huMAP3_10813.1 huMAP3_11096.1
HMOX1	huMAP3_03864.1 huMAP3_04862.1 huMAP3_06323.1 huMAP3_07761.1 huMAP3_09833.1 huMAP3_10678.1