hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09846.1
Complex Portal: CPX-23900
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CYP3A43 | Cytochrome P450 3A43 (EC 1.14.14.1) | 5 | UniProt NCBI |
| CEACAM5 | Carcinoembryonic antigen-related cell adhesion molecule 5 (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD antigen CD66e) | 5 | UniProt NCBI |
| ANXA3 | Annexin A3 (35-alpha calcimedin) (Annexin III) (Annexin-3) (Inositol 1,2-cyclic phosphate 2-phosphohydrolase) (Lipocortin III) (Placental anticoagulant protein III) (PAP-III) | 5 | UniProt NCBI |
| MMP8 | Neutrophil collagenase (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL) | 5 | UniProt NCBI |
| ARHGDIB | Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Ly-GDI) (Rho-GDI beta) | 5 | UniProt NCBI |
| SMIM8 | Small integral membrane protein 8 | 2 | UniProt NCBI |
| APCS | Serum amyloid P-component (SAP) (9.5S alpha-1-glycoprotein) [Cleaved into: Serum amyloid P-component(1-203)] | 5 | UniProt NCBI |
| EGFL8 | Epidermal growth factor-like protein 8 (EGF-like protein 8) (Vascular endothelial statin-2) (VE-statin-2) | 5 | UniProt NCBI |
| CADPS2 | Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2) | 5 | UniProt NCBI |
| ITGAM | Integrin alpha-M (CD11 antigen-like family member B) (CR-3 alpha chain) (Cell surface glycoprotein MAC-1 subunit alpha) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD antigen CD11b) | 5 | UniProt NCBI |
| GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (Gamma-9) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7177 | 0.0499842271994 | 0.111111111111 | GNG8 | GNAS-L-GNB3-GNG8 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MMP8 | SMIM8 | 0.994 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ITGAM | CYP3A43 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CYP3A43 | ARHGDIB | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ARHGDIB | EGFL8 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CEACAM5 | GNG8 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CADPS2 | GNG8 | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| GNG8 | APCS | 0.982 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| EGFL8 | APCS | 0.975 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MMP8 | GNG8 | 0.973 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ITGAM | GNG8 | 0.971 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ANXA3 | GNG8 | 0.971 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ITGAM | MMP8 | 0.785 | bioplex3_WMM WMM_only | ||
| ITGAM | APCS | 0.784 | 0.23 | bioplex3_WMM WMM_only | |
| GNG8 | ARHGDIB | 0.742 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ARHGDIB | APCS | 0.709 | 0.09 | bioplex3_WMM WMM_only | |
| ITGAM | ARHGDIB | 0.667 | 0.108 | bioplex3_WMM WMM_only | |
| MMP8 | APCS | 0.433 | bioplex3_WMM WMM_only | ||
| MMP8 | ARHGDIB | 0.433 | bioplex3_WMM WMM_only | ||
| CEACAM5 | CADPS2 | 0.415 | bioplex3_WMM WMM_only | ||
| CADPS2 | MMP8 | 0.415 | bioplex3_WMM WMM_only | ||
| CADPS2 | ITGAM | 0.278 | bioplex3_WMM WMM_only | ||
| CEACAM5 | MMP8 | 0.274 | bioplex3_WMM WMM_only | ||
| CEACAM5 | ITGAM | 0.25 | 0.21 | bioplex3_WMM WMM_only | |
| CADPS2 | ARHGDIB | 0.113 | bioplex3_WMM WMM_only | ||
| CADPS2 | APCS | 0.113 | bioplex3_WMM WMM_only | ||
| CEACAM5 | APCS | 0.095 | 0.27 | bioplex3_WMM WMM_only | |
| CADPS2 | ANXA3 | 0.093 | bioplex3_WMM WMM_only | ||
| ANXA3 | ARHGDIB | 0.079 | 0.12 | bioplex3_WMM WMM_only | |
| CEACAM5 | ARHGDIB | 0.078 | 0.112 | bioplex3_WMM WMM_only | |
| ANXA3 | MMP8 | 0.065 | bioplex3_WMM WMM_only | ||
| CEACAM5 | ANXA3 | 0.065 | 0.096 | bioplex3_WMM WMM_only | |
| ANXA3 | APCS | 0.065 | 0.128 | bioplex3_WMM WMM_only | |
| ITGAM | ANXA3 | 0.063 | 0.112 | bioplex3_WMM WMM_only | |
| ANXA3 | EGFL8 | 0.002 | bioplex3_HCT116 WMM_only | ||
| ANXA3 | SMIM8 | 0.002 | 0.03 | bioplex3_HCT116 WMM_only | |
| CYP3A43 | ANXA3 | 0.002 | bioplex3_HCT116 WMM_only |
Related Complexes