hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
WWTR1	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)	5	UniProt NCBI
TEAD3	Transcriptional enhancer factor TEF-5 (DTEF-1) (TEA domain family member 3) (TEAD-3)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8951671	4.78453290596e-05	1.0	WWTR1 TEAD3	RUNX3 regulates YAP1-mediated transcription
KEGG:04392	5.28351507038e-05	1.0	WWTR1 TEAD3	Hippo signaling pathway - multiple species
WP:WP4537	7.2783930122e-05	1.0	WWTR1 TEAD3	Hippo YAP signaling
REAC:R-HSA-2032785	0.000112778275641	1.0	WWTR1 TEAD3	YAP1- and WWTR1 (TAZ)-stimulated gene expression
WP:WP4534	0.000331996874241	1.0	WWTR1 TEAD3	Mechanoregulation and pathology of YAP TAZ via Hippo and non Hippo mechanisms
WP:WP4540	0.00141354053763	1.0	WWTR1 TEAD3	Hippo signaling regulation pathways
KEGG:04390	0.001720800216	1.0	WWTR1 TEAD3	Hippo signaling pathway
WP:WP4541	0.00194090480325	1.0	WWTR1 TEAD3	Hippo Merlin signaling dysregulation
REAC:R-HSA-8878159	0.00654113998715	1.0	WWTR1 TEAD3	Transcriptional regulation by RUNX3
CORUM:6652	0.0249718442457	0.5	WWTR1	WWTR1 homodimer
CORUM:7062	0.0249718442457	0.5	WWTR1	NFAT5-WWTR1 complex
WP:WP5087	0.0293715080819	1.0	WWTR1 TEAD3	Pleural mesothelioma
CORUM:6647	0.0499419797295	0.5	WWTR1	MED15-WWTR1 complex
CORUM:6651	0.0499419797295	0.5	WWTR1	WWTR1-YAP1 complex
CORUM:6661	0.0499419797295	0.5	WWTR1	NEK8-WWTR1 complex
CORUM:6676	0.0499419797295	0.5	WWTR1	WWTR1-YWHAQ complex

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
TEAD3	WWTR1	0.997	0.136	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116

Genename	Complexes
WWTR1	huMAP3_01616.1 huMAP3_05786.1 huMAP3_09850.1 huMAP3_10235.1 huMAP3_12897.1 huMAP3_13677.1 huMAP3_14575.1 huMAP3_14671.1
TEAD3	huMAP3_00366.1 huMAP3_06611.1 huMAP3_09850.1 huMAP3_10051.1 huMAP3_10235.1 huMAP3_12897.1 huMAP3_13677.1 huMAP3_14671.1