hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09872.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MMP3 | Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) | 5 | UniProt NCBI |
| TIGD7 | Tigger transposable element-derived protein 7 | 3 | UniProt NCBI |
| MMEL1 | Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))] | 5 | UniProt NCBI |
| MMP10 | Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP129 | 0.000484429625977 | 0.5 | MMP10 MMP3 | Matrix metalloproteinases |
| WP:WP5283 | 0.0013446069671 | 0.5 | MMP10 MMP3 | Chronic hyperglycemia impairment of neuron function |
| REAC:R-HSA-1592389 | 0.00282403231951 | 0.5 | MMP10 MMP3 | Activation of Matrix Metalloproteinases |
| REAC:R-HSA-1442490 | 0.0120053783973 | 0.5 | MMP10 MMP3 | Collagen degradation |
| GO:0004222 | 0.0209740664347 | 0.75 | MMP10 MMP3 MMEL1 | metalloendopeptidase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MMP3 | MMP10 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MMP3 | MMEL1 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MMP3 | TIGD7 | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MMEL1 | MMP10 | 0.902 | bioplex3_WMM WMM_only |
Related Complexes