hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09888.1
Complex Portal: CPX-19079
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARGLU1 | Arginine and glutamate-rich protein 1 | 4 | UniProt NCBI |
| SRSF11 | Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11) | 5 | UniProt NCBI |
| PRPF40A | Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6) | 5 | UniProt NCBI |
| SRRM2 | Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:351 | 0.00029210434484 | 0.75 | SRRM2 SRSF11 PRPF40A | Spliceosome |
| HPA:0080133 | 0.00179344174456 | 1.0 | PRPF40A ARGLU1 SRRM2 SRSF11 | caudate; neuronal cells[High] |
| REAC:R-HSA-72163 | 0.00185188916926 | 0.75 | SRRM2 SRSF11 PRPF40A | mRNA Splicing - Major Pathway |
| HPA:0620223 | 0.00195430669363 | 1.0 | PRPF40A ARGLU1 SRRM2 SRSF11 | vagina; squamous epithelial cells[High] |
| REAC:R-HSA-72172 | 0.002052480752 | 0.75 | SRRM2 SRSF11 PRPF40A | mRNA Splicing |
| HPA:0241103 | 0.0020779229764 | 1.0 | PRPF40A ARGLU1 SRRM2 SRSF11 | heart muscle; cardiomyocytes[High] |
| REAC:R-HSA-72203 | 0.00469213914253 | 0.75 | SRRM2 SRSF11 PRPF40A | Processing of Capped Intron-Containing Pre-mRNA |
| HPA:0430053 | 0.00577234238213 | 1.0 | PRPF40A ARGLU1 SRRM2 SRSF11 | seminal vesicle; glandular cells[High] |
| HPA:0090163 | 0.00655790581157 | 1.0 | PRPF40A ARGLU1 SRRM2 SRSF11 | cerebellum; Purkinje cells[High] |
| HPA:0570733 | 0.0113500251897 | 1.0 | PRPF40A ARGLU1 SRRM2 SRSF11 | testis; Leydig cells[High] |
| HPA:0350473 | 0.0165893993359 | 1.0 | PRPF40A ARGLU1 SRRM2 SRSF11 | pancreas; exocrine glandular cells[High] |
| HPA:0610833 | 0.0196320462024 | 1.0 | PRPF40A ARGLU1 SRRM2 SRSF11 | urinary bladder; urothelial cells[High] |
| HPA:0300202 | 0.0217404024918 | 0.75 | SRRM2 ARGLU1 SRSF11 | lung; endothelial cells[>=Medium] |
| HPA:0100123 | 0.0296286402726 | 0.75 | SRRM2 ARGLU1 SRSF11 | cerebral cortex; glial cells[High] |
| HPA:0090183 | 0.0296286402726 | 0.75 | SRRM2 ARGLU1 SRSF11 | cerebellum; cells in granular layer[High] |
| HPA:0300201 | 0.0401447172992 | 0.75 | SRRM2 ARGLU1 SRSF11 | lung; endothelial cells[>=Low] |
| HPA:0540053 | 0.0408047952341 | 1.0 | PRPF40A ARGLU1 SRRM2 SRSF11 | stomach 1; glandular cells[High] |
| HPA:0480053 | 0.048862114603 | 1.0 | PRPF40A ARGLU1 SRRM2 SRSF11 | small intestine; glandular cells[High] |
| CORUM:2833 | 0.049938562206 | 0.25 | SRRM2 | SRm160-SRm300 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SRRM2 | ARGLU1 | 0.997 | 0.078 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction | |
| SRRM2 | PRPF40A | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM | ||
| SRSF11 | ARGLU1 | 0.958 | bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction | ||
| SRSF11 | SRRM2 | 0.957 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction | ||
| SRSF11 | PRPF40A | 0.779 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | ||
| PRPF40A | ARGLU1 | 0.092 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes