hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09905.1

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
CCDC9	Coiled-coil domain-containing protein 9	4	UniProt NCBI
MAGOH	Protein mago nashi homolog	5	UniProt NCBI
MAGOHB	Protein mago nashi homolog 2	5	UniProt NCBI
EIF4A3	Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]	5	UniProt NCBI
PNN	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein)	5	UniProt NCBI
NKAPD1	Uncharacterized protein NKAPD1 (NKAP domain containing protein 1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0035145	8.36907803204e-10	0.833333333333	CCDC9 EIF4A3 MAGOHB PNN MAGOH	exon-exon junction complex
KEGG:03015	1.08162471848e-06	0.666666666667	MAGOH MAGOHB PNN EIF4A3	mRNA surveillance pathway
KEGG:03013	1.65053510706e-06	0.666666666667	MAGOH MAGOHB PNN EIF4A3	Nucleocytoplasmic transport
REAC:R-HSA-72163	9.37134126241e-05	0.666666666667	MAGOH MAGOHB PNN EIF4A3	mRNA Splicing - Major Pathway
CORUM:769	0.000102488289015	0.333333333333	MAGOH EIF4A3	Exon junction complex (EIF4A3, MLN51, MAGOH, Y14)
CORUM:754	0.000102488289015	0.333333333333	MAGOH EIF4A3	Exon junction complex (EIF4A3, MLN51, UPF3B, MAGOH, Y14)
CORUM:740	0.000102488289015	0.333333333333	MAGOH EIF4A3	Exon junction complex (EIF4A3, MLN51, MAGOH, Y14)
CORUM:744	0.000102488289015	0.333333333333	MAGOH EIF4A3	Exon junction complex (EIF4A3, MLN51, MAGOH, Y14)
REAC:R-HSA-72172	0.00010749190045	0.666666666667	MAGOH MAGOHB PNN EIF4A3	mRNA Splicing
CORUM:755	0.000170782642132	0.333333333333	MAGOH EIF4A3	Exon junction complex (EIF4A3, MLN51, UPF3B, MAGOH, Y14, PYM)
REAC:R-HSA-72187	0.000183939263613	0.5	MAGOH MAGOHB EIF4A3	mRNA 3'-end processing
CORUM:6742	0.00025612721106	0.333333333333	MAGOH EIF4A3	SMG1-UPF2-Y14-MAGOH-UPF3B-EIF4A3 complex
REAC:R-HSA-73856	0.00027807877525	0.5	MAGOH MAGOHB EIF4A3	RNA Polymerase II Transcription Termination
GO:2000622	0.000316805542726	0.5	MAGOH MAGOHB EIF4A3	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
REAC:R-HSA-72203	0.000323589152469	0.666666666667	MAGOH MAGOHB PNN EIF4A3	Processing of Capped Intron-Containing Pre-mRNA
CORUM:1181	0.000338266778162	0.5	MAGOH PNN EIF4A3	C complex spliceosome
CORUM:785	0.000358512652571	0.333333333333	MAGOH EIF4A3	Exon junction complex
REAC:R-HSA-159236	0.00038290615081	0.5	MAGOH MAGOHB EIF4A3	Transport of Mature mRNA derived from an Intron-Containing Transcript
REAC:R-HSA-72202	0.000552388845795	0.5	MAGOH MAGOHB EIF4A3	Transport of Mature Transcript to Cytoplasm
KEGG:03040	0.000620541886073	0.5	MAGOH MAGOHB EIF4A3	Spliceosome
GO:0071013	0.000870570917794	0.666666666667	MAGOH MAGOHB PNN EIF4A3	catalytic step 2 spliceosome
REAC:R-HSA-927802	0.00167064168535	0.5	MAGOH MAGOHB EIF4A3	Nonsense-Mediated Decay (NMD)
REAC:R-HSA-975957	0.00167064168535	0.5	MAGOH MAGOHB EIF4A3	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
REAC:R-HSA-9010553	0.00515963455837	0.5	MAGOH MAGOHB EIF4A3	Regulation of expression of SLITs and ROBOs
REAC:R-HSA-376176	0.0104146574261	0.5	MAGOH MAGOHB EIF4A3	Signaling by ROBO receptors
GO:0000184	0.0104402436969	0.5	MAGOH MAGOHB EIF4A3	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
WP:WP5362	0.0117481700727	0.333333333333	MAGOH EIF4A3	TAR syndrome
REAC:R-HSA-8953854	0.0121605407448	0.666666666667	MAGOH MAGOHB PNN EIF4A3	Metabolism of RNA
GO:0005681	0.013015960717	0.666666666667	MAGOH MAGOHB PNN EIF4A3	spliceosomal complex
GO:1990501	0.0210651876021	0.333333333333	MAGOH MAGOHB	exon-exon junction subcomplex mago-y14
GO:1903503	0.0210651876021	0.333333333333	MAGOH MAGOHB	ATPase inhibitor complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
CCDC9	EIF4A3	1.0	0.1	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein ()
PNN	CCDC9	0.999	0.158	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein ()
MAGOH	CCDC9	0.998		hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only
PNN	EIF4A3	0.996	0.896	hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM
MAGOH	MAGOHB	0.994		hein_WMM bioplex3_WMM hein () gupta_WMM
EIF4A3	NKAPD1	0.994	0.146	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
CCDC9	MAGOHB	0.99	0.058	hein_WMM bioplex3_WMM hein ()
MAGOH	NKAPD1	0.986		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
MAGOH	PNN	0.982		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM
CCDC9	NKAPD1	0.981	0.078	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
MAGOH	EIF4A3	0.978		hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
PNN	MAGOHB	0.97	0.766	hein_WMM bioplex3_WMM WMM_only
PNN	NKAPD1	0.968	0.098	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
MAGOHB	EIF4A3	0.869	0.84	hein_WMM bioplex3_WMM gupta_WMM WMM_only

Related Complexes

Genename	Complexes
CCDC9	huMAP3_01312.1 huMAP3_01567.1 huMAP3_02633.1 huMAP3_04872.1 huMAP3_05069.1 huMAP3_05740.1 huMAP3_05846.1 huMAP3_06219.1 huMAP3_06799.1 huMAP3_07267.1 huMAP3_07561.1 huMAP3_07674.1 huMAP3_08186.1 huMAP3_08302.1 huMAP3_09101.1 huMAP3_09226.1 huMAP3_09552.1 huMAP3_09905.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1
MAGOH	huMAP3_00837.1 huMAP3_04073.1 huMAP3_06443.1 huMAP3_07098.1 huMAP3_07208.1 huMAP3_07561.1 huMAP3_07904.1 huMAP3_08344.1 huMAP3_09621.1 huMAP3_09787.1 huMAP3_09905.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1
MAGOHB	huMAP3_01312.1 huMAP3_04073.1 huMAP3_06443.1 huMAP3_06799.1 huMAP3_07674.1 huMAP3_07904.1 huMAP3_08082.1 huMAP3_08344.1 huMAP3_09149.1 huMAP3_09621.1 huMAP3_09787.1 huMAP3_09905.1 huMAP3_10789.1 huMAP3_11073.1
EIF4A3	huMAP3_01312.1 huMAP3_02633.1 huMAP3_04872.1 huMAP3_05069.1 huMAP3_05740.1 huMAP3_05846.1 huMAP3_06799.1 huMAP3_07561.1 huMAP3_07674.1 huMAP3_08186.1 huMAP3_08302.1 huMAP3_09101.1 huMAP3_09226.1 huMAP3_09552.1 huMAP3_09621.1 huMAP3_09905.1 huMAP3_09943.1 huMAP3_10299.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_12548.1
PNN	huMAP3_00837.1 huMAP3_01312.1 huMAP3_05740.1 huMAP3_06391.1 huMAP3_06799.1 huMAP3_07098.1 huMAP3_07267.1 huMAP3_07561.1 huMAP3_07674.1 huMAP3_08082.1 huMAP3_08302.1 huMAP3_08344.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09787.1 huMAP3_09905.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1
NKAPD1	huMAP3_02633.1 huMAP3_02972.1 huMAP3_06097.1 huMAP3_06799.1 huMAP3_07098.1 huMAP3_07674.1 huMAP3_08467.1 huMAP3_09621.1 huMAP3_09905.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_11073.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09905.1