List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_09908.1

Confidence: Moderate High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
GTF2H2C	General transcription factor IIH subunit 2-like protein (General transcription factor IIH polypeptide 2-like protein)	4	UniProt   NCBI
GTF2H2	General transcription factor IIH subunit 2 (Basic transcription factor 2 44 kDa subunit) (BTF2 p44) (General transcription factor IIH polypeptide 2) (TFIIH basal transcription factor complex p44 subunit)	5	UniProt   NCBI
GTF2H4	General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit)	5	UniProt   NCBI
CDK7	Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)	5	UniProt   NCBI
ERCC2	General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein)	5	UniProt   NCBI
GTF2H1	General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit)	5	UniProt   NCBI
ERCC3	General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)	5	UniProt   NCBI
ERCC5	DNA excision repair protein ERCC-5 (EC 3.1.-.-) (DNA repair protein complementing XP-G cells) (Xeroderma pigmentosum group G-complementing protein)	5	UniProt   NCBI
GTF2H5	General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit) (TFIIH subunit p8)	5	UniProt   NCBI
SCO1	Protein SCO1 homolog, mitochondrial	5	UniProt   NCBI
CCNH	Cyclin-H (MO15-associated protein) (p34) (p37)	5	UniProt   NCBI
GTF2H3	General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit)	5	UniProt   NCBI
MNAT1	CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Cyclin-G1-interacting protein) (Menage a trois) (RING finger protein 66) (RING finger protein MAT1) (p35) (p36)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:1029	3.28665753178e-32	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	TFIIH transcription factor complex
CORUM:1009	3.28665753178e-32	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	TFIIH transcription factor complex
GO:0005675	4.4392406675e-32	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	transcription factor TFIIH holo complex
GO:0000439	2.70163249112e-29	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	transcription factor TFIIH core complex
CORUM:107	1.60016399697e-28	0.75	CDK7 GTF2H1 CCNH ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 MNAT1	TFIIH transcription factor complex
CORUM:1036	1.60016399697e-28	0.75	CDK7 GTF2H1 CCNH ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 MNAT1	TFIIH transcription factor complex
GO:0032806	6.210336932e-28	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	carboxy-terminal domain protein kinase complex
REAC:R-HSA-77075	7.78357914082e-25	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Pol II CTD phosphorylation and interaction with CE
REAC:R-HSA-167160	7.78357914082e-25	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
REAC:R-HSA-72086	1.92252265668e-24	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	mRNA Capping
REAC:R-HSA-73863	6.49511918424e-24	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase I Transcription Termination
REAC:R-HSA-113418	9.44626844363e-24	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Formation of the Early Elongation Complex
REAC:R-HSA-167158	9.44626844363e-24	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Formation of the HIV-1 Early Elongation Complex
KEGG:03022	3.13630025771e-23	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Basal transcription factors
WP:WP4753	1.2052979452e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Nucleotide excision repair
REAC:R-HSA-167200	2.15188977692e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Formation of HIV-1 elongation complex containing HIV-1 Tat
REAC:R-HSA-167246	2.15188977692e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Tat-mediated elongation of the HIV-1 transcript
REAC:R-HSA-167169	2.15188977692e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	HIV Transcription Elongation
REAC:R-HSA-5696395	2.15188977692e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Formation of Incision Complex in GG-NER
REAC:R-HSA-167152	3.62777164848e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Formation of HIV elongation complex in the absence of HIV Tat
REAC:R-HSA-73779	4.66369595494e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
REAC:R-HSA-75953	4.66369595494e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase II Transcription Initiation
REAC:R-HSA-73776	4.66369595494e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase II Promoter Escape
REAC:R-HSA-167162	4.66369595494e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase II HIV Promoter Escape
REAC:R-HSA-167161	4.66369595494e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	HIV Transcription Initiation
REAC:R-HSA-76042	4.66369595494e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase II Transcription Initiation And Promoter Clearance
REAC:R-HSA-73762	7.56786399997e-22	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase I Transcription Initiation
KEGG:03420	1.45663884807e-21	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Nucleotide excision repair
REAC:R-HSA-6781823	2.31069072776e-21	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Formation of TC-NER Pre-Incision Complex
GO:0016591	5.65140847775e-21	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	RNA polymerase II, holoenzyme
REAC:R-HSA-112382	6.30342525302e-21	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Formation of RNA Pol II elongation complex
REAC:R-HSA-75955	6.30342525302e-21	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase II Transcription Elongation
REAC:R-HSA-6796648	1.31565880088e-20	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	TP53 Regulates Transcription of DNA Repair Genes
REAC:R-HSA-6782210	1.86417988871e-20	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Gap-filling DNA repair synthesis and ligation in TC-NER
REAC:R-HSA-6782135	2.20912243505e-20	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Dual incision in TC-NER
WP:WP5114	3.89124355176e-20	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Nucleotide excision repair in xeroderma pigmentosum
REAC:R-HSA-167172	4.23828550816e-20	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Transcription of the HIV genome
WP:WP405	8.35529116681e-20	0.75	CDK7 GTF2H1 CCNH ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 MNAT1	Eukaryotic transcription initiation
REAC:R-HSA-6781827	1.59728514184e-19	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Transcription-Coupled Nucleotide Excision Repair (TC-NER)
GO:0055029	1.97850691682e-19	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	nuclear DNA-directed RNA polymerase complex
REAC:R-HSA-674695	2.09718890865e-19	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase II Pre-transcription Events
REAC:R-HSA-73772	2.09718890865e-19	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase I Promoter Escape
GO:0000428	2.24377481495e-19	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	DNA-directed RNA polymerase complex
GO:0030880	3.24521478758e-19	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	RNA polymerase complex
REAC:R-HSA-5696399	3.53895904601e-19	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Global Genome Nucleotide Excision Repair (GG-NER)
REAC:R-HSA-427413	1.3136624815e-18	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	NoRC negatively regulates rRNA expression
REAC:R-HSA-5250941	1.82663038433e-18	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Negative epigenetic regulation of rRNA expression
REAC:R-HSA-73854	2.03394741315e-18	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase I Promoter Clearance
REAC:R-HSA-73864	2.26219763507e-18	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	RNA Polymerase I Transcription
WP:WP4946	3.86907756381e-18	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	DNA repair pathways full network
REAC:R-HSA-5696398	5.61643506755e-18	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Nucleotide Excision Repair
GO:1902554	7.46207059312e-18	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	serine/threonine protein kinase complex
GO:1902911	3.16811394854e-17	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	protein kinase complex
REAC:R-HSA-162599	3.8532972678e-17	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Late Phase of HIV Life Cycle
REAC:R-HSA-162587	9.59308685895e-17	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	HIV Life Cycle
REAC:R-HSA-212165	6.48325414676e-16	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Epigenetic regulation of gene expression
GO:0090575	1.87245234098e-15	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	RNA polymerase II transcription regulator complex
REAC:R-HSA-3700989	2.75324954712e-15	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH SCO1 MNAT1	Transcriptional Regulation by TP53
CORUM:1037	8.6757634689e-15	0.416666666667	GTF2H4 GTF2H3 GTF2H2 ERCC3 GTF2H1	TFIIH transcription factor core complex
REAC:R-HSA-162906	8.90756595686e-15	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	HIV Infection
GO:0061695	5.27292120873e-14	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	transferase complex, transferring phosphorus-containing groups
CORUM:103	1.122661522e-13	0.5	GTF2H1 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3	RNA polymerase II holoenzyme complex
REAC:R-HSA-5696400	1.69725455382e-13	0.583333333333	GTF2H5 GTF2H1 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3	Dual Incision in GG-NER
CORUM:2825	2.24374134259e-13	0.5	GTF2H1 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3	BRCA1-RNA polymerase II complex
REAC:R-HSA-73894	2.41863095065e-13	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	DNA Repair
GO:0005667	9.91408569403e-13	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	transcription regulator complex
CORUM:1030	1.58451975055e-11	0.333333333333	CDK7 CCNH MNAT1 ERCC2	CAK-ERCC2 complex
CORUM:2660	1.58451975055e-11	0.333333333333	CDK7 CCNH MNAT1 ERCC2	CAK-ERCC2 complex
REAC:R-HSA-212436	5.86407783059e-10	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH SCO1 MNAT1	Generic Transcription Pathway
REAC:R-HSA-8953854	7.7925639851e-10	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Metabolism of RNA
REAC:R-HSA-9824446	1.02418743414e-09	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Viral Infection Pathways
REAC:R-HSA-73857	1.95832618224e-09	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH SCO1 MNAT1	RNA Polymerase II Transcription
GO:0005669	2.49370856712e-09	0.5	GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3	transcription factor TFIID complex
GO:0006289	3.62927949326e-09	0.583333333333	GTF2H5 GTF2H2C ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3	nucleotide-excision repair
GO:1990234	5.1209373747e-09	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	transferase complex
REAC:R-HSA-74160	7.75358168203e-09	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH SCO1 MNAT1	Gene expression (Transcription)
REAC:R-HSA-5663205	7.98078204297e-09	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Infectious disease
GO:0140535	9.65007281378e-09	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	intracellular protein-containing complex
GO:0070516	1.30247523495e-08	0.333333333333	CDK7 CCNH MNAT1 ERCC2	CAK-ERCC2 complex
CORUM:1008	2.5725558439e-08	0.25	CDK7 MNAT1 CCNH	CAK complex (Cdk-activating kinase complex)
CORUM:1010	2.5725558439e-08	0.25	CDK7 MNAT1 CCNH	CAK complex (Cdk-activating kinase complex)
GO:0140513	2.48722376184e-07	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	nuclear protein-containing complex
GO:0006281	4.48429717219e-07	0.75	GTF2H5 GTF2H2C ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 GTF2H1	DNA repair
CORUM:2657	5.13798447177e-07	0.25	CDK7 MNAT1 CCNH	ESR1-CDK7-CCNH-MNAT1-MTA1-HDAC2 complex
REAC:R-HSA-1643685	1.68852491518e-06	0.833333333333	CDK7 GTF2H1 GTF2H5 ERCC2 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH MNAT1	Disease
GO:1902494	8.57493687429e-06	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	catalytic complex
GO:0006974	1.52881499687e-05	0.75	GTF2H5 GTF2H2C ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 GTF2H1	DNA damage response
GO:0019907	2.11464090368e-05	0.25	CDK7 MNAT1 CCNH	cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0000438	2.11464090368e-05	0.25	GTF2H4 GTF2H2 GTF2H3	core TFIIH complex portion of holo TFIIH complex
GO:0070985	2.11464090368e-05	0.25	CDK7 MNAT1 CCNH	transcription factor TFIIK complex
GO:0006259	2.65786297502e-05	0.75	GTF2H5 GTF2H2C ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 GTF2H1	DNA metabolic process
HP:0007381	3.69037581507e-05	0.25	ERCC2 ERCC3 GTF2H5	Congenital exfoliative erythroderma
HP:0410219	3.69037581507e-05	0.25	ERCC2 ERCC3 GTF2H5	Hypoplasia of mandible relative to maxilla
CORUM:1007	3.75927585468e-05	0.166666666667	CDK7 CCNH	CAK core complex (Cdk-activating kinase core complex)
HP:0045055	5.26952972096e-05	0.25	ERCC2 ERCC3 GTF2H5	Tiger tail banding
GO:0006366	5.54683142428e-05	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	transcription by RNA polymerase II
HP:0001809	7.2422557061e-05	0.25	ERCC2 ERCC3 GTF2H5	Split nail
HP:0002562	9.65187935018e-05	0.25	ERCC2 ERCC3 GTF2H5	Low-set nipples
HP:0007587	9.65187935018e-05	0.25	ERCC2 ERCC3 GTF2H5	Numerous pigmented freckles
HP:0006538	0.000125416456279	0.25	ERCC2 ERCC3 GTF2H5	Recurrent bronchopulmonary infections
HP:0025428	0.000125416456279	0.25	ERCC2 ERCC3 GTF2H5	Bronchospasm
HP:0025548	0.000159547189976	0.25	ERCC2 ERCC3 GTF2H5	Increased mean corpuscular hemoglobin concentration
HP:0007034	0.000199341834895	0.25	ERCC2 ERCC3 GTF2H5	Generalized hyperreflexia
HP:0003079	0.000199341834895	0.25	ERCC2 ERCC3 GTF2H5	Defective DNA repair after ultraviolet radiation damage
HP:0001598	0.000245230427941	0.25	ERCC2 ERCC3 GTF2H5	Concave nail
REAC:R-HSA-69273	0.000261656080241	0.25	CDK7 MNAT1 CCNH	Cyclin A/B1/B2 associated events during G2/M transition
HP:0000320	0.000297642203506	0.25	ERCC2 ERCC3 GTF2H5	Bird-like facies
HP:0003139	0.000357005594351	0.25	ERCC2 ERCC3 GTF2H5	Panhypogammaglobulinemia
HP:0025546	0.000357005594351	0.25	ERCC2 ERCC3 GTF2H5	Abnormal mean corpuscular hemoglobin concentration
HP:0007485	0.000357005594351	0.25	ERCC2 ERCC3 GTF2H5	Absence of subcutaneous fat
HP:0007266	0.000357005594351	0.25	ERCC2 ERCC3 GTF2H5	Cerebral dysmyelination
HP:0003254	0.000423748232485	0.25	ERCC2 ERCC3 GTF2H5	Abnormality of DNA repair
HP:0025427	0.00049829695005	0.25	ERCC2 ERCC3 GTF2H5	Abnormal bronchus physiology
HP:0100275	0.00049829695005	0.25	ERCC2 ERCC3 GTF2H5	Diffuse cerebellar atrophy
HP:0007479	0.000581077780197	0.25	ERCC2 ERCC3 GTF2H5	Congenital nonbullous ichthyosiform erythroderma
KEGG:05203	0.000603372367254	0.333333333333	GTF2H4 GTF2H3 GTF2H2 GTF2H1	Viral carcinogenesis
HP:0007633	0.000773035921177	0.25	ERCC2 ERCC3 GTF2H5	Bilateral microphthalmos
GO:0016251	0.000847864556543	0.333333333333	GTF2H4 GTF2H3 GTF2H2 CCNH	RNA polymerase II general transcription initiation factor activity
HP:0007431	0.00127439453065	0.25	ERCC2 ERCC3 GTF2H5	Congenital ichthyosiform erythroderma
HP:0001807	0.00127439453065	0.25	ERCC2 ERCC3 GTF2H5	Ridged nail
GO:0006351	0.00129352492083	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	DNA-templated transcription
HP:0001808	0.00142666214653	0.25	ERCC2 ERCC3 GTF2H5	Fragile nails
GO:0032774	0.00145229192484	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	RNA biosynthetic process
HP:0000133	0.00159054148198	0.25	ERCC2 ERCC3 GTF2H5	Gonadal dysgenesis
REAC:R-HSA-69236	0.00171024179687	0.25	CDK7 MNAT1 CCNH	G1 Phase
REAC:R-HSA-69231	0.00171024179687	0.25	CDK7 MNAT1 CCNH	Cyclin D associated events in G1
HP:0008391	0.00176645141874	0.25	ERCC2 ERCC3 GTF2H5	Dystrophic fingernails
WP:WP45	0.00200126363655	0.25	CDK7 MNAT1 CCNH	G1 to S cell cycle control
CORUM:3066	0.00205912795651	0.166666666667	GTF2H3 ERCC3	RNA polymerase II complex, chromatin structure modifying
HP:0008887	0.00215603467286	0.25	ERCC2 ERCC3 GTF2H5	Adipose tissue loss
HP:0003328	0.00237054180605	0.25	ERCC2 ERCC3 GTF2H5	Abnormal hairshaft morphology
GO:0140223	0.00248592852225	0.333333333333	GTF2H4 GTF2H3 GTF2H2 CCNH	general transcription initiation factor activity
GO:0033554	0.00272519459561	0.75	GTF2H5 GTF2H2C ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 GTF2H1	cellular response to stress
CORUM:1141	0.00291755409055	0.166666666667	GTF2H4 ERCC3	CF IIAm complex (Cleavage factor IIAm complex)
HP:0002293	0.00427882394974	0.25	ERCC2 ERCC3 GTF2H5	Alopecia of scalp
HP:0001097	0.00461449131351	0.25	ERCC2 ERCC3 GTF2H5	Keratoconjunctivitis sicca
HP:0006970	0.00533722209806	0.25	ERCC2 ERCC3 GTF2H5	Periventricular leukomalacia
GO:0034654	0.00564313932845	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	nucleobase-containing compound biosynthetic process
HP:0002299	0.00613120157568	0.25	ERCC2 ERCC3 GTF2H5	Brittle hair
HP:0001096	0.00655592688799	0.25	ERCC2 ERCC3 GTF2H5	Keratoconjunctivitis
GO:0018130	0.00687055826053	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	heterocycle biosynthetic process
GO:0019438	0.00694976884025	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	aromatic compound biosynthetic process
HP:0040063	0.00699968359616	0.25	ERCC2 ERCC3 GTF2H5	Decreased adipose tissue
HP:0002942	0.00844918612904	0.25	ERCC2 ERCC3 GTF2H5	Thoracic kyphosis
GO:1901362	0.00949722550579	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	organic cyclic compound biosynthetic process
REAC:R-HSA-69202	0.00981270863023	0.25	CDK7 MNAT1 CCNH	Cyclin E associated events during G1/S transition
HP:0001338	0.0100844972532	0.25	ERCC2 ERCC3 GTF2H5	Partial agenesis of the corpus callosum
REAC:R-HSA-69656	0.0105479772019	0.25	CDK7 MNAT1 CCNH	Cyclin A:Cdk2-associated events at S phase entry
GO:0150005	0.0117710605412	0.25	CDK7 MNAT1 CCNH	enzyme activator complex
HP:0012760	0.0119164419935	0.25	ERCC2 ERCC3 GTF2H5	Reduced social reciprocity
HP:0001019	0.0125726486101	0.25	ERCC2 ERCC3 GTF2H5	Erythroderma
HP:0004337	0.0134884857584	0.166666666667	ERCC2 ERCC3	Abnormality of amino acid metabolism
HP:0000656	0.0139557830468	0.25	ERCC2 ERCC3 GTF2H5	Ectropion
GO:0019908	0.0142868257683	0.25	CDK7 MNAT1 CCNH	nuclear cyclin-dependent protein kinase holoenzyme complex
HP:0002860	0.0146835027354	0.25	ERCC2 ERCC3 GTF2H5	Squamous cell carcinoma
HP:0002828	0.0154358507084	0.25	ERCC2 ERCC3 GTF2H5	Multiple joint contractures
HP:0010649	0.0179764430521	0.166666666667	ERCC2 ERCC3	Flat nasal alae
HP:0008619	0.0186993944851	0.25	ERCC2 ERCC3 GTF2H5	Bilateral sensorineural hearing impairment
REAC:R-HSA-8939236	0.0269428931759	0.25	CDK7 MNAT1 CCNH	RUNX1 regulates transcription of genes involved in differentiation of HSCs
HP:0000491	0.0276357905628	0.25	ERCC2 ERCC3 GTF2H5	Keratitis
GO:0016070	0.0295140519053	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	RNA metabolic process
HP:0000608	0.0323727565724	0.25	ERCC2 ERCC3 GTF2H5	Macular degeneration
REAC:R-HSA-69206	0.0387692716976	0.25	CDK7 MNAT1 CCNH	G1/S Transition
HP:0009886	0.0422957757477	0.166666666667	ERCC2 GTF2H5	Trichorrhexis nodosa
HP:0006297	0.0433879456849	0.25	ERCC2 ERCC3 GTF2H5	Enamel hypoplasia
HP:0002080	0.048079633907	0.25	ERCC2 ERCC3 GTF2H5	Intention tremor
GO:0044271	0.0482066228902	0.916666666667	CDK7 GTF2H1 GTF2H5 ERCC2 MNAT1 GTF2H2 GTF2H4 ERCC3 GTF2H3 CCNH GTF2H2C	cellular nitrogen compound biosynthetic process
HP:0000509	0.0497145292647	0.25	ERCC2 ERCC3 GTF2H5	Conjunctivitis



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
GTF2H4	ERCC3	1.0	0.256
GTF2H2	GTF2H1	1.0	0.404
CDK7	CCNH	1.0	0.344
GTF2H2	GTF2H3	1.0	0.648
GTF2H2	ERCC3	1.0	0.286
GTF2H4	GTF2H1	1.0	0.162
CCNH	MNAT1	1.0	0.476
GTF2H1	GTF2H3	1.0	0.354
CDK7	MNAT1	1.0	0.376
GTF2H4	GTF2H3	1.0	0.402
GTF2H1	ERCC3	1.0	0.296
GTF2H4	GTF2H2C	1.0	0.122
GTF2H4	GTF2H5	1.0	0.264
ERCC3	GTF2H2C	1.0	0.26
GTF2H5	GTF2H3	1.0	0.434
GTF2H2	GTF2H5	1.0	0.41
ERCC3	GTF2H3	1.0	0.456
GTF2H1	GTF2H2C	1.0	0.118
GTF2H2	GTF2H4	1.0	0.26
ERCC3	GTF2H5	1.0	0.196
GTF2H2C	GTF2H3	1.0	0.124
GTF2H1	GTF2H5	1.0	0.428
ERCC2	CCNH	0.999	0.172
CDK7	ERCC2	0.999	0.278
ERCC2	MNAT1	0.999	0.388
ERCC3	MNAT1	0.998	0.120086956522
GTF2H5	CCNH	0.998	0.196
GTF2H2C	GTF2H5	0.997	0.166
GTF2H4	MNAT1	0.995	0.218
ERCC2	GTF2H1	0.992	0.224
ERCC5	GTF2H3	0.991	0.02
ERCC5	GTF2H2	0.991	0.042
CDK7	ERCC3	0.99	0.262
ERCC5	ERCC3	0.99	0.06
CDK7	GTF2H5	0.989	0.354
GTF2H5	MNAT1	0.989	0.444
ERCC5	CCNH	0.988	0.032
ERCC5	SCO1	0.987	0.056
GTF2H4	CDK7	0.986	0.31
ERCC2	GTF2H5	0.986	0.318
ERCC5	GTF2H4	0.985	0.028
GTF2H2	MNAT1	0.984	0.618
ERCC5	GTF2H5	0.984	0.08
ERCC5	MNAT1	0.976	0.058
ERCC2	ERCC3	0.975	0.248
GTF2H3	MNAT1	0.975	0.458
ERCC5	GTF2H1	0.974	0.038
GTF2H4	ERCC2	0.972	0.326
CDK7	GTF2H3	0.971	0.464
GTF2H2	CDK7	0.969	0.522
CCNH	GTF2H3	0.968	0.234
GTF2H1	CCNH	0.968	0.064
GTF2H4	CCNH	0.968	0.12
GTF2H1	MNAT1	0.959	0.316
ERCC5	CDK7	0.955	0.042
ERCC5	ERCC2	0.95	0.09
CDK7	GTF2H1	0.946	0.248
ERCC3	CCNH	0.944	0.212
ERCC2	GTF2H3	0.935	0.426
CDK7	GTF2H2C	0.924	0.132
GTF2H2	ERCC2	0.921	0.262
GTF2H2	CCNH	0.91	0.304
GTF2H2C	MNAT1	0.544	0.064
SCO1	ERCC3	0.238	0.098
SCO1	GTF2H1	0.162	0.084
SCO1	GTF2H4	0.125	0.158677484787
GTF2H2	GTF2H2C	0.079	0.138
SCO1	MNAT1	0.061	0.12
SCO1	GTF2H5	0.057	0.16
SCO1	GTF2H3	0.056	0.306
SCO1	CDK7	0.04	0.196
SCO1	CCNH	0.029	0.108
SCO1	GTF2H2	0.017	0.08
SCO1	ERCC2	0.012	0.046
ERCC2	GTF2H2C	0.008	0.27





Related Complexes

Genename	Complexes
GTF2H2C	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1 huMAP3_15000.1
GTF2H2	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
GTF2H4	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
CDK7	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
ERCC2	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
GTF2H1	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
ERCC3	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
ERCC5	huMAP3_04170.1 huMAP3_09908.1 huMAP3_12429.1
GTF2H5	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
SCO1	huMAP3_04170.1 huMAP3_09908.1 huMAP3_12868.1
CCNH	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1 huMAP3_14722.1
GTF2H3	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
MNAT1	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1