hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09932.1
Complex Portal: CPX-15410
Confidence: Medium High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BHMT2 | S-methylmethionine--homocysteine S-methyltransferase BHMT2 (SMM-hcy methyltransferase) (EC 2.1.1.10) (Betaine--homocysteine S-methyltransferase 2) | 5 | UniProt   NCBI |
| TBCE | Tubulin-specific chaperone E (Tubulin-folding cofactor E) | 5 | UniProt   NCBI |
| BHMT | Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) | 5 | UniProt   NCBI |
| SFTA2 | Surfactant-associated protein 2 (Surfactant-associated protein G) (SP-G) | 3 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   KEGG:00270 | 0.000788502734463 | 0.666666666667 | BHMT BHMT2 | Cysteine and methionine metabolism |
|   WP:WP3940 | 0.00102095428698 | 0.666666666667 | BHMT BHMT2 | One carbon metabolism and related pathways |
|   WP:WP2525 | 0.00167805708824 | 0.666666666667 | BHMT BHMT2 | Trans sulfuration one carbon metabolism and related pathways |
|   REAC:R-HSA-1614635 | 0.00172341693863 | 0.666666666667 | BHMT BHMT2 | Sulfur amino acid metabolism |
|   GO:0008172 | 0.0140440992017 | 0.666666666667 | BHMT BHMT2 | S-methyltransferase activity |
|   GO:0043102 | 0.0294899169624 | 0.666666666667 | BHMT BHMT2 | amino acid salvage |
|   GO:0071265 | 0.0294899169624 | 0.666666666667 | BHMT BHMT2 | L-methionine biosynthetic process |
|   GO:0071267 | 0.0294899169624 | 0.666666666667 | BHMT BHMT2 | L-methionine salvage |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  BHMT2 |  BHMT | 0.996 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  TBCE |  SFTA2 | 0.977 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  TBCE |  BHMT2 | 0.964 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  TBCE |  BHMT | 0.128 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| BHMT2 | huMAP3_01625.1 huMAP3_04491.1 huMAP3_06947.1 huMAP3_09932.1 |
| TBCE | huMAP3_00912.1 huMAP3_04491.1 huMAP3_09932.1 |
| BHMT | huMAP3_01625.1 huMAP3_09932.1 |
| SFTA2 | huMAP3_00912.1 huMAP3_09932.1 |