hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09946.1
Complex Portal: CPX-19141
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PAPLN | Papilin | 5 | UniProt NCBI |
| ADAMTS13 | A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAM-TS 13) (ADAM-TS13) (ADAMTS-13) (EC 3.4.24.87) (von Willebrand factor-cleaving protease) (vWF-CP) (vWF-cleaving protease) | 5 | UniProt NCBI |
| B3GLCT | Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta 3-glucosyltransferase) (Beta-3-glycosyltransferase-like) | 5 | UniProt NCBI |
| C2CD4B | C2 calcium-dependent domain-containing protein 4B (Nuclear-localized factor 2) (Protein FAM148B) | 4 | UniProt NCBI |
| PDGFC | Platelet-derived growth factor C (PDGF-C) (Fallotein) (Spinal cord-derived growth factor) (SCDGF) (VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form); Platelet-derived growth factor C, receptor-binding form (PDGFC receptor-binding form)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5083635 | 0.00259338296865 | 0.4 | ADAMTS13 B3GLCT | Defective B3GALTL causes PpS |
| REAC:R-HSA-5173214 | 0.00288114202251 | 0.4 | ADAMTS13 B3GLCT | O-glycosylation of TSR domain-containing proteins |
| REAC:R-HSA-3906995 | 0.0130168285242 | 0.4 | ADAMTS13 B3GLCT | Diseases associated with O-glycosylation of proteins |
| REAC:R-HSA-5173105 | 0.0440242300692 | 0.4 | ADAMTS13 B3GLCT | O-linked glycosylation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ADAMTS13 | C2CD4B | 0.99 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| B3GLCT | PAPLN | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ADAMTS13 | PDGFC | 0.987 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| B3GLCT | ADAMTS13 | 0.977 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| B3GLCT | C2CD4B | 0.102 | bioplex3_WMM WMM_only | ||
| B3GLCT | PDGFC | 0.102 | bioplex3_WMM WMM_only | ||
| C2CD4B | PDGFC | 0.076 | bioplex3_WMM WMM_only |
Related Complexes