hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09955.1
Complex Portal: CPX-21588
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SNX12 | Sorting nexin-12 | 5 | UniProt NCBI |
| SNX3 | Sorting nexin-3 (Protein SDP3) | 5 | UniProt NCBI |
| TMTC4 | Protein O-mannosyl-transferase TMTC4 (EC 2.4.1.109) (Transmembrane O-mannosyltransferase targeting cadherins 4) (Transmembrane and tetratricopeptide repeat-containing 4) | 5 | UniProt NCBI |
| SLC6A15 | Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Sodium-coupled branched-chain amino-acid transporter 1) (Solute carrier family 6 member 15) (Transporter v7-3) | 5 | UniProt NCBI |
| FAM217B | Protein FAM217B | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:2000642 | 0.00468200720083 | 0.4 | SNX12 SNX3 | negative regulation of early endosome to late endosome transport |
| GO:0034499 | 0.0468008499735 | 0.4 | SNX12 SNX3 | late endosome to Golgi transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SNX3 | SNX12 | 0.993 | 0.48 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction | |
| FAM217B | SNX12 | 0.99 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TMTC4 | SLC6A15 | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SNX12 | TMTC4 | 0.972 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SNX3 | SLC6A15 | 0.078 | 0.122 | bioplex3_WMM gupta_WMM WMM_only | |
| SNX12 | SLC6A15 | 0.003 | 0.06 | bioplex3_WMM WMM_only |
Related Complexes