hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09963.1

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
SUV39H2	Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Lysine N-methyltransferase 1B) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)	5	UniProt NCBI
ZNF776	Zinc finger protein 776	3	UniProt NCBI
ZMYM4	Zinc finger MYM-type protein 4 (Zinc finger protein 262)	5	UniProt NCBI
ADNP2	Activity-dependent neuroprotector homeobox protein 2 (ADNP homeobox protein 2) (Zinc finger protein 508)	4	UniProt NCBI
CHAMP1	Chromosome alignment-maintaining phosphoprotein 1 (Zinc finger protein 828)	5	UniProt NCBI
CBX5	Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)	5	UniProt NCBI
ZNF280C	Zinc finger protein 280C (Suppressor of hairy wing homolog 3) (Zinc finger protein 633)	4	UniProt NCBI
ZNF428	Zinc finger protein 428 (Enzyme-like protein PIT13)	2	UniProt NCBI
SUV39H1	Histone-lysine N-methyltransferase SUV39H1 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Lysine N-methyltransferase 1A) (Position-effect variegation 3-9 homolog) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1)	5	UniProt NCBI
ADNP	Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein)	5	UniProt NCBI
MAD2L2	Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (REV7 homolog) (hREV7)	5	UniProt NCBI
CBX1	Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)	5	UniProt NCBI
CBX3	Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)	5	UniProt NCBI
MAGEC1	Melanoma-associated antigen C1 (Cancer/testis antigen 7.1) (CT7.1) (MAGE-C1 antigen)	3	UniProt NCBI
ZNF581	Zinc finger protein 581	5	UniProt NCBI
POGZ	Pogo transposable element with ZNF domain (Suppressor of hairy wing homolog 5) (Zinc finger protein 280E) (Zinc finger protein 635)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP4320	6.89295132642e-06	0.25	SUV39H1 CBX3 CBX5 CBX1	Effect of progerin on genes involved in Hutchinson Gilford progeria syndrome
CORUM:2763	5.10764421909e-05	0.125	SUV39H1 CBX5	MBD1-Suv39h1-HP1 complex
HPA:0250123	0.00134910636785	0.375	ADNP CBX1 POGZ CHAMP1 CBX5 ZNF280C	hippocampus; glial cells[High]
HPA:0570783	0.00655302356542	0.375	ADNP CBX1 POGZ CBX3 CHAMP1 ZNF280C	testis; preleptotene spermatocytes[High]
GO:0006357	0.00718413926088	0.6875	ADNP MAGEC1 CBX1 MAD2L2 SUV39H2 CBX3 SUV39H1 CBX5 POGZ ZNF776 ZNF581	regulation of transcription by RNA polymerase II
GO:0000785	0.00917299254895	0.5625	ADNP CBX1 MAD2L2 SUV39H2 CBX3 SUV39H1 CBX5 POGZ ADNP2	chromatin
GO:0006355	0.0115370464873	0.75	ADNP MAGEC1 CBX1 POGZ ZNF280C SUV39H2 CBX3 SUV39H1 CBX5 MAD2L2 ZNF776 ZNF581	regulation of DNA-templated transcription
GO:0000792	0.0116031794561	0.25	SUV39H1 CBX3 CBX5 CBX1	heterochromatin
GO:2001141	0.0123556667956	0.75	ADNP MAGEC1 CBX1 POGZ ZNF280C SUV39H2 CBX3 SUV39H1 CBX5 MAD2L2 ZNF776 ZNF581	regulation of RNA biosynthetic process
GO:0006366	0.0125053648941	0.6875	ADNP MAGEC1 CBX1 MAD2L2 SUV39H2 CBX3 SUV39H1 CBX5 POGZ ZNF776 ZNF581	transcription by RNA polymerase II
GO:0005694	0.0144200186666	0.625	ADNP SUV39H1 MAD2L2 SUV39H2 CBX3 CHAMP1 CBX1 CBX5 POGZ ADNP2	chromosome
GO:0032993	0.0152070409739	0.5625	ADNP CBX1 MAD2L2 SUV39H2 CBX3 SUV39H1 CBX5 POGZ ADNP2	protein-DNA complex
GO:0006351	0.0197251377193	0.75	ADNP MAGEC1 CBX1 POGZ ZNF280C SUV39H2 CBX3 SUV39H1 CBX5 MAD2L2 ZNF776 ZNF581	DNA-templated transcription
GO:0032774	0.0222553679442	0.75	ADNP MAGEC1 CBX1 POGZ ZNF280C SUV39H2 CBX3 SUV39H1 CBX5 MAD2L2 ZNF776 ZNF581	RNA biosynthetic process
HPA:0570782	0.0323069855684	0.4375	ADNP MAGEC1 CBX1 ZNF280C CBX3 CHAMP1 POGZ	testis; preleptotene spermatocytes[>=Medium]
GO:0051252	0.0407627055642	0.75	ADNP MAGEC1 CBX1 POGZ ZNF280C SUV39H2 CBX3 SUV39H1 CBX5 MAD2L2 ZNF776 ZNF581	regulation of RNA metabolic process

Edges

Protein 1	Protein 2	Score	ProteomeHD
ADNP	ZNF581	0.999	0.104
ZNF428	CHAMP1	0.999	0.108
CBX5	CBX3	0.999	0.482
ZNF428	POGZ	0.999	0.044
CBX3	CBX1	0.999	0.294
CBX5	CBX1	0.998	0.104
SUV39H2	CBX5	0.998	0.198
CHAMP1	POGZ	0.997	0.656
ADNP2	CBX3	0.997	0.2
SUV39H1	CBX5	0.997	0.21
ZNF428	MAD2L2	0.996	0.066
SUV39H1	CBX1	0.995	0.104
SUV39H1	MAGEC1	0.995	0.112
SUV39H1	CBX3	0.994	0.234
SUV39H2	CBX3	0.994	0.23
ZNF581	CBX1	0.993	0.062
CBX5	ZNF776	0.991
CHAMP1	CBX3	0.99	0.186
ZMYM4	MAD2L2	0.989	0.202
SUV39H2	CBX1	0.989	0.084
ZMYM4	CBX5	0.987	0.136
ADNP2	CBX1	0.986	0.058
CBX5	POGZ	0.985	0.112
POGZ	CBX1	0.982	0.054
CBX3	ZNF581	0.982	0.112
ZNF776	CBX3	0.981
CHAMP1	CBX5	0.98	0.132
ZMYM4	CHAMP1	0.98	0.18
CBX3	POGZ	0.977	0.172
MAD2L2	POGZ	0.976	0.188
MAD2L2	CBX3	0.965	0.31
ZNF280C	CBX3	0.965	0.094
CHAMP1	MAD2L2	0.964	0.242
ZNF280C	CBX1	0.955	0.058
ZMYM4	POGZ	0.953	0.352
ZNF280C	POGZ	0.948	0.196
ZNF776	CBX1	0.943
ZNF280C	CBX5	0.94	0.104
CHAMP1	CBX1	0.939	0.108
ZMYM4	CBX3	0.934	0.258
ADNP	CBX3	0.916	0.298
ADNP2	CBX5	0.905	0.172
ADNP2	ZMYM4	0.905	0.12
ADNP2	ZNF280C	0.887	0.154
MAD2L2	CBX1	0.876	0.252
MAD2L2	ZNF280C	0.863	0.094
ZMYM4	CBX1	0.857	0.092
ADNP	ZMYM4	0.855	0.46
ADNP	CBX5	0.844	0.176
ZMYM4	ZNF280C	0.832	0.154
ZNF428	CBX3	0.738	0.082
ADNP2	MAD2L2	0.708	0.218
ADNP	CBX1	0.67	0.054
MAD2L2	CBX5	0.63	0.268
ADNP	CHAMP1	0.564	0.442
ZNF280C	SUV39H2	0.415	0.158
SUV39H2	ZNF581	0.415	0.16
ADNP2	POGZ	0.369	0.218
SUV39H1	POGZ	0.358	0.18
ADNP	SUV39H1	0.288	0.3
ZNF428	CBX1	0.274	0.072
ZNF280C	ZNF581	0.274	0.146
ADNP2	CHAMP1	0.259	0.15
ADNP2	SUV39H2	0.25	0.152
MAGEC1	CBX3	0.249	0.124
ADNP2	SUV39H1	0.234	0.18
ADNP	ZNF280C	0.234	0.142
SUV39H1	ZNF280C	0.232	0.21
SUV39H1	MAD2L2	0.232	0.198
MAGEC1	CBX1	0.194	0.1
ZNF428	CBX5	0.188	0.026
MAGEC1	CBX5	0.187	0.112
SUV39H1	CHAMP1	0.131	0.118
ADNP2	ZNF581	0.113	0.152
ADNP	ADNP2	0.108	0.17
MAD2L2	SUV39H2	0.102	0.112
MAD2L2	ZNF581	0.097	0.146
CHAMP1	SUV39H2	0.095	0.108
CHAMP1	ZNF280C	0.092	0.134
ADNP	MAD2L2	0.088	0.224
ZMYM4	ZNF581	0.08	0.076
SUV39H2	POGZ	0.078	0.112
CHAMP1	ZNF581	0.078	0.09
ADNP	SUV39H2	0.078	0.314
POGZ	ZNF581	0.076	0.082
ZMYM4	SUV39H2	0.064	0.114
CBX5	ZNF581	0.064	0.104
ADNP	POGZ	0.055	0.566
ZMYM4	SUV39H1	0.048	0.234
MAD2L2	ZNF776	0.014
ZNF280C	ZNF776	0.014
ZNF776	POGZ	0.006
ZMYM4	ZNF776	0.006
CHAMP1	ZNF776	0.006
ADNP	ZNF776	0.004

Related Complexes

Genename	Complexes
SUV39H2	huMAP3_02606.1 huMAP3_02835.1 huMAP3_06309.1 huMAP3_06469.1 huMAP3_07089.1 huMAP3_07851.1 huMAP3_09071.1 huMAP3_09963.1 huMAP3_10512.1 huMAP3_11539.1 huMAP3_12731.1 huMAP3_12768.1 huMAP3_12927.1
ZNF776	huMAP3_02835.1 huMAP3_03467.1 huMAP3_06309.1 huMAP3_07304.1 huMAP3_07851.1 huMAP3_09071.1 huMAP3_09963.1 huMAP3_10843.1
ZMYM4	huMAP3_00780.1 huMAP3_01309.1 huMAP3_03699.1 huMAP3_07073.1 huMAP3_07496.1 huMAP3_08464.1 huMAP3_09232.1 huMAP3_09692.1 huMAP3_09963.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_11539.1
ADNP2	huMAP3_00559.1 huMAP3_02309.1 huMAP3_02835.1 huMAP3_03712.1 huMAP3_06309.1 huMAP3_07089.1 huMAP3_07851.1 huMAP3_09071.1 huMAP3_09963.1 huMAP3_10737.1 huMAP3_12510.1 huMAP3_15205.1
CHAMP1	huMAP3_01309.1 huMAP3_03699.1 huMAP3_07496.1 huMAP3_09963.1 huMAP3_11539.1
CBX5	huMAP3_02606.1 huMAP3_06309.1 huMAP3_06469.1 huMAP3_07089.1 huMAP3_07851.1 huMAP3_09071.1 huMAP3_09963.1 huMAP3_10512.1 huMAP3_11539.1
ZNF280C	huMAP3_02372.1 huMAP3_02835.1 huMAP3_06309.1 huMAP3_07089.1 huMAP3_07851.1 huMAP3_09071.1 huMAP3_09963.1 huMAP3_11539.1
ZNF428	huMAP3_01309.1 huMAP3_03699.1 huMAP3_07496.1 huMAP3_09963.1 huMAP3_11539.1 huMAP3_15218.1
SUV39H1	huMAP3_01127.1 huMAP3_07162.1 huMAP3_09963.1 huMAP3_14652.1
ADNP	huMAP3_00075.1 huMAP3_00780.1 huMAP3_01874.1 huMAP3_04478.1 huMAP3_06802.1 huMAP3_07073.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08464.1 huMAP3_09046.1 huMAP3_09071.1 huMAP3_09232.1 huMAP3_09582.1 huMAP3_09707.1 huMAP3_09963.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_11539.1
MAD2L2	huMAP3_01309.1 huMAP3_03699.1 huMAP3_07496.1 huMAP3_09963.1 huMAP3_11539.1
CBX1	huMAP3_06309.1 huMAP3_07089.1 huMAP3_07851.1 huMAP3_09071.1 huMAP3_09963.1 huMAP3_11468.1 huMAP3_11539.1
CBX3	huMAP3_02835.1 huMAP3_06309.1 huMAP3_07089.1 huMAP3_07851.1 huMAP3_09071.1 huMAP3_09963.1 huMAP3_11539.1
MAGEC1	huMAP3_01127.1 huMAP3_09963.1 huMAP3_14652.1
ZNF581	huMAP3_04478.1 huMAP3_06309.1 huMAP3_09046.1 huMAP3_09071.1 huMAP3_09963.1 huMAP3_11468.1 huMAP3_11539.1 huMAP3_12251.1
POGZ	huMAP3_03699.1 huMAP3_07496.1 huMAP3_09963.1 huMAP3_11539.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09963.1