hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09971.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DEF8 | Differentially expressed in FDCP 8 homolog (DEF-8) | 4 | UniProt NCBI |
| NLRP7 | NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3) | 5 | UniProt NCBI |
| PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-I) (PLC-I) (Phospholipase C-beta-1) (PLC-beta-1) | 5 | UniProt NCBI |
| PLEKHM3 | Pleckstrin homology domain-containing family M member 3 (PH domain-containing family M member 3) (Differentiation associated protein) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04621 | 0.02620193588 | 0.5 | NLRP7 PLCB1 | NOD-like receptor signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NLRP7 | DEF8 | 0.999 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| DEF8 | PLCB1 | 0.987 | 0.19 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PLEKHM3 | DEF8 | 0.983 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| NLRP7 | PLCB1 | 0.055 | bioplex3_WMM WMM_only |
Related Complexes