hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10002.1
Complex Portal: CPX-13600
Confidence: Medium High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCDH18 | Protocadherin-18 | 4 | UniProt   NCBI |
| PCDHGC3 | Protocadherin gamma-C3 (PCDH-gamma-C3) (Protocadherin-2) (Protocadherin-43) (PC-43) | 4 | UniProt   NCBI |
| FAT4 | Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) | 5 | UniProt   NCBI |
| PCDH17 | Protocadherin-17 (Protocadherin-68) | 5 | UniProt   NCBI |
| PCDH12 | Protocadherin-12 (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cad-2) (VE-cadherin-2) [Cleaved into: Protocadherin-12, secreted form] | 5 | UniProt   NCBI |
| PCDHGA11 | Protocadherin gamma-A11 (PCDH-gamma-A11) | 4 | UniProt   NCBI |
| DCBLD1 | Discoidin, CUB and LCCL domain-containing protein 1 | 3 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   GO:0007155 | 0.0199049916893 | 0.857142857143 | FAT4 PCDHGA11 PCDH12 PCDH17 PCDH18 PCDHGC3 | cell adhesion |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  PCDH18 |  PCDH12 | 0.988 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  PCDH17 |  PCDH12 | 0.97 |            |
structurally_consistent (dimer)        
|
bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  PCDH12 |  DCBLD1 | 0.957 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  PCDH12 |  PCDHGA11 | 0.956 |            |
structurally_consistent (dimer)        
|
bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  PCDH12 |  PCDHGC3 | 0.954 |            |
structurally_consistent (dimer)        
|
bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  PCDHGA11 |  FAT4 | 0.951 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  PCDHGA11 |  PCDHGC3 | 0.951 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  FAT4 |  PCDHGC3 | 0.819 | 0.118           |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  PCDH17 |  PCDHGA11 | 0.644 |            |
mutually_exclusive (Q9NPG4)        
|
bioplex_WMM     bioplex3_WMM     WMM_only     |
|  PCDH18 |  PCDHGA11 | 0.581 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  PCDH18 |  PCDHGC3 | 0.35 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  PCDH17 |  PCDHGC3 | 0.35 |            |
mutually_exclusive (Q9NPG4)        
|
bioplex_WMM     bioplex3_WMM     WMM_only     |
|  PCDH18 |  PCDH17 | 0.328 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  PCDH18 |  DCBLD1 | 0.262 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  DCBLD1 |  PCDHGC3 | 0.218 | 0.086           |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  PCDH17 |  DCBLD1 | 0.218 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  DCBLD1 |  PCDHGA11 | 0.218 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  PCDH18 |  FAT4 | 0.145 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  DCBLD1 |  FAT4 | 0.063 | 0.158           |          | bioplex3_WMM     WMM_only     |
|  PCDH17 |  FAT4 | 0.056 |            |          | bioplex3_WMM     WMM_only     |
Related Complexes