hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10013.1
Complex Portal: CPX-22864
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NEURL4 | Neuralized-like protein 4 | 4 | UniProt NCBI |
| USP16 | Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-processing protease UBP-M) (Ubiquitin-specific-processing protease 16) | 5 | UniProt NCBI |
| HERC2 | E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) | 5 | UniProt NCBI |
| PRIMPOL | DNA-directed primase/polymerase protein (hPrimpol1) (EC 2.7.7.-) (Coiled-coil domain-containing protein 111) | 5 | UniProt NCBI |
| SPZ1 | Spermatogenic leucine zipper protein 1 (Testis-specific protein 1) (Testis-specific protein NYD-TSP1) | 4 | UniProt NCBI |
| ECI2 | Enoyl-CoA delta isomerase 2 (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1) | 5 | UniProt NCBI |
| ZNF286A | Zinc finger protein 286A | 5 | UniProt NCBI |
| FBXL5 | F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein) | 5 | UniProt NCBI |
| ANKRD26 | Ankyrin repeat domain-containing protein 26 | 5 | UniProt NCBI |
| ECH1 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-) | 5 | UniProt NCBI |
| MAP7D2 | MAP7 domain-containing protein 2 | 3 | UniProt NCBI |
| ZBTB5 | Zinc finger and BTB domain-containing protein 5 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6860 | 0.000225350794349 | 0.166666666667 | NEURL4 HERC2 | E6AP-HERC2-MAPK6-NEURL4 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ECI2 | ECH1 | 1.0 | 0.122 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo bioplex3_HCT116 fraction treiber_WMM | |
| HERC2 | NEURL4 | 0.998 | 0.084 | hein_WMM bioplex_WMM bioplex3_WMM hein () gupta_WMM boldt_WMM | |
| HERC2 | USP16 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| NEURL4 | USP16 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| NEURL4 | FBXL5 | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| HERC2 | ZNF286A | 0.983 | 0.136 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| HERC2 | SPZ1 | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| HERC2 | PRIMPOL | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| NEURL4 | ECH1 | 0.975 | 0.062 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HERC2 | FBXL5 | 0.972 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| HERC2 | ZBTB5 | 0.972 | hein_WMM bioplex3_WMM hein () | ||
| HERC2 | MAP7D2 | 0.966 | 0.112 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ZNF286A | NEURL4 | 0.964 | 0.122 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ANKRD26 | NEURL4 | 0.964 | 0.256 | hein_WMM bioplex3_WMM hein () | |
| PRIMPOL | NEURL4 | 0.953 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| NEURL4 | ECI2 | 0.951 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only | |
| FBXL5 | ECH1 | 0.951 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SPZ1 | NEURL4 | 0.946 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MAP7D2 | NEURL4 | 0.937 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| HERC2 | ECH1 | 0.928 | 0.058 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| HERC2 | ECI2 | 0.884 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZBTB5 | NEURL4 | 0.796 | hein_WMM WMM_only | ||
| HERC2 | ANKRD26 | 0.645 | 0.158 | hein_WMM bioplex3_WMM hein () | |
| ECI2 | FBXL5 | 0.622 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PRIMPOL | ECH1 | 0.593 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF286A | ECI2 | 0.56 | 0.044 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MAP7D2 | ECI2 | 0.522 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PRIMPOL | ECI2 | 0.389 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZBTB5 | ANKRD26 | 0.359 | hein_WMM hein () | ||
| ECI2 | USP16 | 0.339 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZBTB5 | ECI2 | 0.18 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ECH1 | USP16 | 0.157 | bioplex3_HEK293 bioplex () bioplex3_WMM youn_WMM | ||
| MAP7D2 | ZBTB5 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | ||
| MAP7D2 | FBXL5 | 0.059 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZBTB5 | ECH1 | 0.054 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| SPZ1 | ECH1 | 0.044 | bioplex3_HEK293 bioplex () | ||
| MAP7D2 | USP16 | 0.024 | youn_WMM WMM_only | ||
| ZNF286A | ECH1 | 0.023 | 0.098 | bioplex3_HEK293 bioplex () | |
| MAP7D2 | ECH1 | 0.022 | 0.134 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM | |
| MAP7D2 | ANKRD26 | 0.016 | 0.126 | bioplex3_WMM youn_WMM WMM_only | |
| ANKRD26 | USP16 | 0.005 | youn_WMM WMM_only | ||
| ANKRD26 | ECH1 | 0.002 | 0.184 | youn_WMM gupta_WMM WMM_only |
Related Complexes