hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10020.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MICU3 | Calcium uptake protein 3, mitochondrial (EF-hand domain-containing family member A2) | 3 | UniProt NCBI |
| MICU1 | Calcium uptake protein 1, mitochondrial (Atopy-related autoantigen CALC) (ara CALC) (Calcium-binding atopy-related autoantigen 1) (allergen Hom s 4) | 5 | UniProt NCBI |
| MICU2 | Calcium uptake protein 2, mitochondrial (EF-hand domain-containing family member A1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8949664 | 2.61297199043e-07 | 1.0 | MICU3 MICU1 MICU2 | Processing of SMDT1 |
| REAC:R-HSA-8949215 | 7.18567297368e-07 | 1.0 | MICU3 MICU1 MICU2 | Mitochondrial calcium ion transport |
| GO:1990246 | 1.92240082153e-06 | 1.0 | MICU3 MICU1 MICU2 | uniplex complex |
| GO:0036444 | 2.11464090368e-05 | 1.0 | MICU3 MICU1 MICU2 | calcium import into the mitochondrion |
| CORUM:6473 | 3.41705576683e-05 | 0.666666666667 | MICU2 MICU1 | mitochondrial calcium uniporter complex |
| GO:0006851 | 5.38272230028e-05 | 1.0 | MICU3 MICU1 MICU2 | mitochondrial calcium ion transmembrane transport |
| GO:0051560 | 7.84339535184e-05 | 1.0 | MICU3 MICU1 MICU2 | mitochondrial calcium ion homeostasis |
| GO:0170036 | 0.00127301382402 | 1.0 | MICU3 MICU1 MICU2 | import into the mitochondrion |
| GO:0034704 | 0.00200169985542 | 1.0 | MICU3 MICU1 MICU2 | calcium channel complex |
| GO:1990542 | 0.00851239083773 | 1.0 | MICU3 MICU1 MICU2 | mitochondrial transmembrane transport |
| REAC:R-HSA-382551 | 0.0117092435511 | 1.0 | MICU3 MICU1 MICU2 | Transport of small molecules |
| GO:0034703 | 0.0343879058955 | 1.0 | MICU3 MICU1 MICU2 | cation channel complex |
| GO:0006839 | 0.0449053607901 | 1.0 | MICU3 MICU1 MICU2 | mitochondrial transport |
| GO:0098800 | 0.0498541011049 | 1.0 | MICU3 MICU1 MICU2 | inner mitochondrial membrane protein complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MICU1 | MICU2 | 0.999 | 0.522 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM |
| MICU1 | MICU3 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MICU2 | MICU3 | 0.161 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MICU3 | huMAP3_00882.1 huMAP3_10020.1 |
| MICU1 | huMAP3_00095.1 huMAP3_00882.1 huMAP3_10020.1 |
| MICU2 | huMAP3_00095.1 huMAP3_06318.1 huMAP3_10020.1 huMAP3_14289.1 |