hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10039.1
Complex Portal: CPX-12932
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BBX | HMG box transcription factor BBX (Bobby sox homolog) (HMG box-containing protein 2) | 5 | UniProt NCBI |
| SENP3 | Sentrin-specific protease 3 (EC 3.4.22.-) (SUMO-1-specific protease 3) (Sentrin/SUMO-specific protease SENP3) | 5 | UniProt NCBI |
| PWP2 | Periodic tryptophan protein 2 homolog | 5 | UniProt NCBI |
| RPS19BP1 | Active regulator of SIRT1 (40S ribosomal protein S19-binding protein 1) (RPS19-binding protein 1) (S19BP) | 5 | UniProt NCBI |
| UTP14A | U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO-16) (Serologically defined colon cancer antigen 16) | 5 | UniProt NCBI |
| PDCD11 | Protein RRP5 homolog (NF-kappa-B-binding protein) (NFBP) (Programmed cell death protein 11) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6791226 | 6.01983866986e-05 | 0.666666666667 | PDCD11 SENP3 PWP2 UTP14A | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 7.47826336784e-05 | 0.666666666667 | PDCD11 SENP3 PWP2 UTP14A | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 9.18586326844e-05 | 0.666666666667 | PDCD11 SENP3 PWP2 UTP14A | rRNA processing |
| REAC:R-HSA-6790901 | 0.000227786945547 | 0.5 | UTP14A PWP2 PDCD11 | rRNA modification in the nucleus and cytosol |
| GO:0032040 | 0.000403034704454 | 0.666666666667 | PDCD11 UTP14A PWP2 RPS19BP1 | small-subunit processome |
| GO:0030684 | 0.00172616540497 | 0.666666666667 | PDCD11 UTP14A PWP2 RPS19BP1 | preribosome |
| REAC:R-HSA-8953854 | 0.0121605407448 | 0.666666666667 | PDCD11 SENP3 PWP2 UTP14A | Metabolism of RNA |
| KEGG:03008 | 0.0188598619414 | 0.333333333333 | UTP14A PWP2 | Ribosome biogenesis in eukaryotes |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BBX | SENP3 | 0.998 | 0.216 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| PWP2 | PDCD11 | 0.991 | 0.874 | hein_WMM bioplex_WMM bioplex3_WMM fraction | |
| SENP3 | PDCD11 | 0.984 | 0.334 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| PWP2 | SENP3 | 0.978 | 0.328 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| BBX | PDCD11 | 0.961 | 0.054 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| RPS19BP1 | PDCD11 | 0.96 | 0.382 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| UTP14A | PDCD11 | 0.96 | 0.926 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| PWP2 | UTP14A | 0.828 | 0.654 | bioplex_WMM bioplex3_WMM WMM_only | |
| BBX | RPS19BP1 | 0.571 | 0.116 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| BBX | PWP2 | 0.476 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only | |
| BBX | UTP14A | 0.461 | 0.124 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| SENP3 | RPS19BP1 | 0.345 | 0.084 | hein_WMM bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RPS19BP1 | UTP14A | 0.141 | 0.53 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SENP3 | UTP14A | 0.109 | 0.324 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only | |
| PWP2 | RPS19BP1 | 0.071 | 0.492 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes