hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10041.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MT1A | Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA) | 5 | UniProt NCBI |
| MT1F | Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF) | 5 | UniProt NCBI |
| MT2A | Metallothionein-2 (MT-2) (Metallothionein-2A) (Metallothionein-II) (MT-II) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5661231 | 9.33204282296e-09 | 1.0 | MT1A MT2A MT1F | Metallothioneins bind metals |
| REAC:R-HSA-5660526 | 1.63310749402e-08 | 1.0 | MT1A MT2A MT1F | Response to metal ions |
| WP:WP3529 | 2.26734774313e-07 | 1.0 | MT1A MT2A MT1F | Zinc homeostasis |
| KEGG:04978 | 8.47057861986e-07 | 1.0 | MT1A MT2A MT1F | Mineral absorption |
| WP:WP3286 | 1.02662405163e-06 | 1.0 | MT1A MT2A MT1F | Copper homeostasis |
| GO:0010273 | 5.38272230028e-06 | 1.0 | MT1A MT2A MT1F | detoxification of copper ion |
| GO:1990169 | 5.38272230028e-06 | 1.0 | MT1A MT2A MT1F | stress response to copper ion |
| GO:0097501 | 1.58598067776e-05 | 1.0 | MT1A MT2A MT1F | stress response to metal ion |
| GO:0071280 | 1.58598067776e-05 | 1.0 | MT1A MT2A MT1F | cellular response to copper ion |
| GO:0071294 | 1.58598067776e-05 | 1.0 | MT1A MT2A MT1F | cellular response to zinc ion |
| GO:0061687 | 2.11464090368e-05 | 1.0 | MT1A MT2A MT1F | detoxification of inorganic compound |
| GO:0046688 | 6.5361627932e-05 | 1.0 | MT1A MT2A MT1F | response to copper ion |
| GO:0010043 | 0.000127839654632 | 1.0 | MT1A MT2A MT1F | response to zinc ion |
| GO:0071276 | 0.000148024863258 | 1.0 | MT1A MT2A MT1F | cellular response to cadmium ion |
| GO:0046686 | 0.000170228592746 | 1.0 | MT1A MT2A MT1F | response to cadmium ion |
| GO:0006882 | 0.000170228592746 | 1.0 | MT1A MT2A MT1F | intracellular zinc ion homeostasis |
| GO:0098754 | 0.00225170808226 | 1.0 | MT1A MT2A MT1F | detoxification |
| GO:0009636 | 0.00649050577369 | 1.0 | MT1A MT2A MT1F | response to toxic substance |
| GO:0071248 | 0.0180186629002 | 1.0 | MT1A MT2A MT1F | cellular response to metal ion |
| GO:0071241 | 0.0263194935275 | 1.0 | MT1A MT2A MT1F | cellular response to inorganic substance |
| REAC:R-HSA-8953897 | 0.0301284815898 | 1.0 | MT1A MT2A MT1F | Cellular responses to stimuli |
| GO:0045926 | 0.0458676185213 | 1.0 | MT1A MT2A MT1F | negative regulation of growth |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MT1A | MT2A | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MT1A | MT1F | 0.974 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes