hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10043.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KDM4A | Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A) | 5 | UniProt NCBI |
| TCEA1 | Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o) | 5 | UniProt NCBI |
| PUS7 | Pseudouridylate synthase 7 homolog (EC 5.4.99.-) | 5 | UniProt NCBI |
| ARHGAP18 | Rho GTPase-activating protein 18 (MacGAP) (Rho-type GTPase-activating protein 18) | 5 | UniProt NCBI |
| PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3) | 5 | UniProt NCBI |
| KDM4B | Lysine-specific demethylase 4B (EC 1.14.11.66) (JmjC domain-containing histone demethylation protein 3B) (Jumonji domain-containing protein 2B) ([histone H3]-trimethyl-L-lysine(9) demethylase 4B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0140684 | 0.0210651876021 | 0.333333333333 | KDM4A KDM4B | histone H3K9me2/H3K9me3 demethylase activity |
| REAC:R-HSA-3214842 | 0.0265097243254 | 0.333333333333 | KDM4A KDM4B | HDMs demethylate histones |
| REAC:R-HSA-73894 | 0.0318872588213 | 0.5 | KDM4A TCEA1 KDM4B | DNA Repair |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| KDM4A | KDM4B | 0.999 | 0.22 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ARHGAP18 | KDM4B | 0.987 | 0.122 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| PUS7 | KDM4B | 0.987 | 0.142 | bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| TCEA1 | KDM4B | 0.983 | 0.11 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| PLCB3 | KDM4B | 0.974 | 0.152 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| TCEA1 | PUS7 | 0.685 | 0.088 | bioplex_WMM bioplex3_WMM fraction |
| TCEA1 | PLCB3 | 0.652 | 0.042 | bioplex3_WMM fraction |
| PUS7 | PLCB3 | 0.487 | 0.064 | bioplex3_WMM WMM_only |
| ARHGAP18 | PLCB3 | 0.487 | 0.06 | bioplex3_WMM WMM_only |
| TCEA1 | ARHGAP18 | 0.473 | 0.074 | bioplex3_WMM WMM_only |
| PUS7 | ARHGAP18 | 0.443 | 0.028 | bioplex3_WMM WMM_only |
| KDM4A | PUS7 | 0.074 | 0.144 | bioplex3_WMM WMM_only |
| KDM4A | PLCB3 | 0.074 | 0.122 | bioplex3_WMM WMM_only |
| TCEA1 | KDM4A | 0.074 | 0.124 | bioplex3_WMM WMM_only |
| KDM4A | ARHGAP18 | 0.074 | 0.082 | bioplex3_WMM WMM_only |
Related Complexes