hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10051.1

Complex Portal: CPX-16189

Confidence: Medium High

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Genename	Protein Name	Uniprot Annotation Score	Links
CTSS	Cathepsin S (EC 3.4.22.27)	5	UniProt NCBI
IRF2	Interferon regulatory factor 2 (IRF-2)	5	UniProt NCBI
IRF2BP1	Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1)	5	UniProt NCBI
IRF2BP2	Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2)	5	UniProt NCBI
IRF2BPL	Probable E3 ubiquitin-protein ligase IRF2BPL (EC 2.3.2.27) (Enhanced at puberty protein 1) (Interferon regulatory factor 2-binding protein-like)	5	UniProt NCBI
TEAD3	Transcriptional enhancer factor TEF-5 (DTEF-1) (TEA domain family member 3) (TEAD-3)	5	UniProt NCBI
VGLL4	Transcription cofactor vestigial-like protein 4 (Vgl-4)	5	UniProt NCBI

Showing 1 to 7 of 7 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6848	2.80233355908e-09	0.6	IRF2BPL IRF2BP2 IRF2BP1	IRF2BP2-IRF2BP1-IRF2BPL complex
WP:WP4541	0.0264781270697	0.4	TEAD3 VGLL4	Hippo Merlin signaling dysregulation

Showing 1 to 2 of 2 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
IRF2BP1	IRF2BP2	1.0	0.082		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
IRF2BPL	IRF2BP1	1.0	0.274		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
VGLL4	TEAD3	1.0	0.066	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
VGLL4	IRF2BPL	0.999	0.064		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
IRF2BPL	IRF2BP2	0.999	0.074		bioplex_WMM bioplex3_WMM Malo fraction
VGLL4	IRF2BP2	0.999	0.088		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
VGLL4	IRF2BP1	0.999	0.166		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
IRF2	CTSS	0.995	0.266		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
IRF2BPL	IRF2	0.995	0.106		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
IRF2BP2	IRF2	0.993	0.09		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM

Showing 1 to 10 of 17 entries

Related Complexes

Genename	Complexes
IRF2	huMAP3_04807.1 huMAP3_05976.1 huMAP3_10051.1 huMAP3_13677.1 huMAP3_14671.1
IRF2BPL	huMAP3_02536.1 huMAP3_05976.1 huMAP3_07039.1 huMAP3_10051.1 huMAP3_13677.1 huMAP3_14671.1
TEAD3	huMAP3_00366.1 huMAP3_06611.1 huMAP3_09850.1 huMAP3_10051.1 huMAP3_10235.1 huMAP3_12897.1 huMAP3_13677.1 huMAP3_14671.1
CTSS	huMAP3_04807.1 huMAP3_10051.1 huMAP3_13677.1 huMAP3_14671.1
IRF2BP1	huMAP3_02536.1 huMAP3_05976.1 huMAP3_06611.1 huMAP3_10051.1 huMAP3_13677.1 huMAP3_14671.1
IRF2BP2	huMAP3_02536.1 huMAP3_05976.1 huMAP3_07039.1 huMAP3_10051.1 huMAP3_13677.1 huMAP3_14671.1
VGLL4	huMAP3_00366.1 huMAP3_06611.1 huMAP3_09040.1 huMAP3_10051.1 huMAP3_10235.1 huMAP3_13677.1 huMAP3_14671.1