hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10056.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LAMA4 | Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha) | 5 | UniProt NCBI |
| MCAM | Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146) | 5 | UniProt NCBI |
| PILRA | Paired immunoglobulin-like type 2 receptor alpha (Cell surface receptor FDF03) (Inhibitory receptor PILR-alpha) | 5 | UniProt NCBI |
| NID2 | Nidogen-2 (NID-2) (Osteonidogen) | 5 | UniProt NCBI |
| PPIB | Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3000157 | 0.00359044851421 | 0.5 | LAMA4 NID2 | Laminin interactions |
| CORUM:2374 | 0.049938562206 | 0.25 | LAMA4 | ITGAV-ITGB3-LAMA4 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LAMA4 | NID2 | 0.988 | 0.264 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| PILRA | NID2 | 0.976 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PPIB | NID2 | 0.973 | 0.168 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| MCAM | LAMA4 | 0.969 | 0.236 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| LAMA4 | PILRA | 0.958 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MCAM | NID2 | 0.095 | 0.104 | bioplex3_WMM WMM_only |
| PPIB | LAMA4 | 0.059 | 0.156 | bioplex3_WMM WMM_only |
| PPIB | PILRA | 0.003 | bioplex3_HEK293 bioplex () bioplex3_HCT116 | |
| PPIB | MCAM | 0.002 | 0.12 | bioplex3_HCT116 WMM_only |
Related Complexes