hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10058.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AZIN1 | Antizyme inhibitor 1 (AZI) (AZI1) (Ornithine decarboxylase antizyme inhibitor) | 5 | UniProt NCBI |
| OAZ1 | Ornithine decarboxylase antizyme 1 (AZ1) (ODC-Az) | 5 | UniProt NCBI |
| OAZ2 | Ornithine decarboxylase antizyme 2 (AZ2) (ODC-Az 2) | 4 | UniProt NCBI |
| AZIN2 | Antizyme inhibitor 2 (AzI2) (Arginine decarboxylase) (ADC) (ARGDC) (Ornithine decarboxylase-like protein) (ODC-like protein) (ornithine decarboxylase paralog) (ODC-p) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0042979 | 1.31563155046e-10 | 1.0 | AZIN2 AZIN1 OAZ2 OAZ1 | ornithine decarboxylase regulator activity |
| GO:0006595 | 2.63389436402e-08 | 1.0 | AZIN2 AZIN1 OAZ2 OAZ1 | polyamine metabolic process |
| REAC:R-HSA-351202 | 3.52714096473e-08 | 1.0 | AZIN2 AZIN1 OAZ2 OAZ1 | Metabolism of polyamines |
| GO:0006576 | 6.05979892141e-06 | 1.0 | AZIN2 AZIN1 OAZ2 OAZ1 | biogenic amine metabolic process |
| GO:0009308 | 1.89640394209e-05 | 1.0 | AZIN2 AZIN1 OAZ2 OAZ1 | amine metabolic process |
| REAC:R-HSA-350562 | 2.7436612495e-05 | 0.75 | AZIN1 OAZ2 OAZ1 | Regulation of ornithine decarboxylase (ODC) |
| REAC:R-HSA-71291 | 4.22186202954e-05 | 1.0 | AZIN2 AZIN1 OAZ2 OAZ1 | Metabolism of amino acids and derivatives |
| GO:0006596 | 4.61210427592e-05 | 0.75 | AZIN2 AZIN1 OAZ1 | polyamine biosynthetic process |
| GO:0042401 | 0.000591522022343 | 0.75 | AZIN2 AZIN1 OAZ1 | biogenic amine biosynthetic process |
| GO:0009309 | 0.000680215375943 | 0.75 | AZIN2 AZIN1 OAZ1 | amine biosynthetic process |
| GO:0042978 | 0.0028092043205 | 0.5 | AZIN1 AZIN2 | ornithine decarboxylase activator activity |
| GO:1902269 | 0.0028092043205 | 0.5 | AZIN1 AZIN2 | positive regulation of polyamine transmembrane transport |
| GO:0042176 | 0.00622455085576 | 1.0 | AZIN2 AZIN1 OAZ2 OAZ1 | regulation of protein catabolic process |
| GO:0008073 | 0.00842684400117 | 0.5 | OAZ1 OAZ2 | ornithine decarboxylase inhibitor activity |
| GO:0033387 | 0.00842684400117 | 0.5 | AZIN1 AZIN2 | putrescine biosynthetic process from ornithine |
| GO:1902267 | 0.00842684400117 | 0.5 | AZIN1 AZIN2 | regulation of polyamine transmembrane transport |
| GO:0009446 | 0.0168521501606 | 0.5 | AZIN1 AZIN2 | putrescine biosynthetic process |
| GO:0009445 | 0.0280843539964 | 0.5 | AZIN1 AZIN2 | putrescine metabolic process |
| REAC:R-HSA-1430728 | 0.0393174957935 | 1.0 | AZIN2 AZIN1 OAZ2 OAZ1 | Metabolism |
| GO:1902047 | 0.042122686785 | 0.5 | AZIN1 AZIN2 | polyamine transmembrane transport |
| CORUM:6642 | 0.049938562206 | 0.25 | OAZ1 | ODC-OAZ1-CCND1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AZIN1 | OAZ1 | 0.999 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () | |
| AZIN2 | OAZ2 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| AZIN1 | OAZ2 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| AZIN2 | OAZ1 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| OAZ1 | OAZ2 | 0.77 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes