hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10065.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LYPLA2 | Acyl-protein thioesterase 2 (APT-2) (EC 3.1.2.-) (Lysophospholipase II) (LPL-II) (LysoPLA II) (Palmitoyl-protein hydrolase) (EC 3.1.2.22) | 5 | UniProt NCBI |
| IL12RB1 | Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212) | 5 | UniProt NCBI |
| ITGB5 | Integrin beta-5 | 5 | UniProt NCBI |
| LOXL2 | Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1566948 | 0.00643909852192 | 0.5 | ITGB5 LOXL2 | Elastic fibre formation |
| CORUM:2019 | 0.0249718442456 | 0.25 | IL12RB1 | IL12A-IL12B-IL12RB1 complex |
| CORUM:2020 | 0.0249718442456 | 0.25 | IL12RB1 | IL12B-IL12RB1-IL12RB2 complex |
| CORUM:2026 | 0.0249718442456 | 0.25 | IL12RB1 | IL12RB1-IL12RB2 complex |
| CORUM:2347 | 0.049938562206 | 0.25 | ITGB5 | ITGAV-ITGB5-SPP1 complex |
| CORUM:2350 | 0.049938562206 | 0.25 | ITGB5 | ITGAV-ITGB5 complex |
| CORUM:5712 | 0.049938562206 | 0.25 | ITGB5 | FAK-beta5 integrin complex, VEGF induced |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IL12RB1 | LYPLA2 | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IL12RB1 | LOXL2 | 0.965 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ITGB5 | LOXL2 | 0.963 | 0.16 | bioplex_WMM bioplex3_WMM WMM_only |
| IL12RB1 | ITGB5 | 0.722 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LOXL2 | LYPLA2 | 0.074 | 0.07 | bioplex3_WMM WMM_only |
| ITGB5 | LYPLA2 | 0.029 | 0.054 | bioplex3_WMM youn_WMM WMM_only |
Related Complexes