hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10074.1
Complex Portal: CPX-14191
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog) | 5 | UniProt NCBI |
| JMJD6 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) | 5 | UniProt NCBI |
| MAPKAPK2 | MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1) | 5 | UniProt NCBI |
| PRPF38A | Pre-mRNA-splicing factor 38A | 5 | UniProt NCBI |
| SCAF11 | Protein SCAF11 (CTD-associated SR protein 11) (Renal carcinoma antigen NY-REN-40) (SC35-interacting protein 1) (SR-related and CTD-associated factor 11) (SRSF2-interacting protein) (Serine/arginine-rich splicing factor 2-interacting protein) (Splicing factor, arginine/serine-rich 2-interacting protein) (Splicing regulatory protein 129) (SRrp129) | 5 | UniProt NCBI |
| SFSWAP | Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog) | 4 | UniProt NCBI |
| RSRC2 | Arginine/serine-rich coiled-coil protein 2 | 5 | UniProt NCBI |
| USP42 | Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.4.19.12) (Deubiquitinating enzyme 42) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| JMJD6 | SFSWAP | 0.998 | 0.054 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| CPSF4 | JMJD6 | 0.998 | 0.054 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| JMJD6 | RSRC2 | 0.997 | 0.036 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| JMJD6 | PRPF38A | 0.996 | 0.088 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction boldt_WMM |
| JMJD6 | SCAF11 | 0.989 | 0.086 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| CPSF4 | MAPKAPK2 | 0.981 | 0.024 | bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| MAPKAPK2 | RSRC2 | 0.979 | 0.018 | bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| JMJD6 | USP42 | 0.968 | 0.108 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MAPKAPK2 | SFSWAP | 0.966 | 0.032 | bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| MAPKAPK2 | SCAF11 | 0.963 | 0.038 | bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| CPSF4 | SFSWAP | 0.894 | 0.21 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| RSRC2 | SFSWAP | 0.62 | 0.068 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| CPSF4 | RSRC2 | 0.55 | 0.246 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| RSRC2 | PRPF38A | 0.458 | 0.1 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| CPSF4 | SCAF11 | 0.434 | 0.216 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| RSRC2 | SCAF11 | 0.391 | 0.05 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| SCAF11 | SFSWAP | 0.314 | 0.168 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| CPSF4 | USP42 | 0.3 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only | |
| PRPF38A | SCAF11 | 0.276 | 0.216 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| USP42 | SFSWAP | 0.247 | 0.2 | bioplex_WMM bioplex3_WMM WMM_only | |
| PRPF38A | SFSWAP | 0.22 | 0.194 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| USP42 | PRPF38A | 0.204 | 0.144 | bioplex_WMM bioplex3_WMM WMM_only | |
| RSRC2 | USP42 | 0.189 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only | |
| CPSF4 | PRPF38A | 0.159 | 0.576 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| USP42 | SCAF11 | 0.12 | 0.198 | bioplex_WMM bioplex3_WMM WMM_only | |
| MAPKAPK2 | PRPF38A | 0.018 | 0.024 | youn_WMM WMM_only |
Related Complexes