hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10089.1

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
CCDC61	Centrosomal protein CCDC61 (Coiled-coil domain-containing protein 61) (VFL3 homolog)	5	UniProt NCBI
CEP97	Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2)	5	UniProt NCBI
CEP290	Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)	5	UniProt NCBI
CCP110	Centriolar coiled-coil protein of 110 kDa (Centrosomal protein of 110 kDa) (CP110) (Cep110)	5	UniProt NCBI
IQCB1	IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ)	5	UniProt NCBI
PHLDB3	Pleckstrin homology-like domain family B member 3	3	UniProt NCBI
KIF24	Kinesin-like protein KIF24	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-5620912	3.77091536836e-08	0.714285714286	CCP110 IQCB1 KIF24 CEP97 CEP290	Anchoring of the basal body to the plasma membrane
REAC:R-HSA-5617833	1.36727427783e-06	0.714285714286	CCP110 IQCB1 KIF24 CEP97 CEP290	Cilium Assembly
REAC:R-HSA-1852241	8.97798177377e-06	0.714285714286	CCP110 IQCB1 KIF24 CEP97 CEP290	Organelle biogenesis and maintenance
CORUM:6597	2.05265451394e-05	0.285714285714	CEP290 IQCB1	CEP290-IQCB1 complex
CORUM:6594	2.05265451394e-05	0.285714285714	CEP290 CCP110	CCP110-CEP290 complex
WP:WP4656	0.000343498567435	0.428571428571	CCP110 CEP97 CEP290	Joubert syndrome
GO:0005813	0.00085857720113	0.857142857143	CCDC61 CCP110 IQCB1 KIF24 CEP290 CEP97	centrosome
GO:0060271	0.00227446778994	0.714285714286	CCP110 IQCB1 KIF24 CEP97 CEP290	cilium assembly
GO:0005815	0.002367221383	0.857142857143	CCDC61 CCP110 IQCB1 KIF24 CEP290 CEP97	microtubule organizing center
GO:1902018	0.00273674384085	0.428571428571	KIF24 CEP97 CCP110	negative regulation of cilium assembly
GO:0044782	0.00323554146091	0.714285714286	CCP110 IQCB1 KIF24 CEP97 CEP290	cilium organization
GO:0005814	0.00449874442284	0.571428571429	CCP110 KIF24 CEP97 CEP290	centriole
GO:0070925	0.00523002441577	0.857142857143	CCDC61 CCP110 IQCB1 KIF24 CEP290 CEP97	organelle assembly
WP:WP4352	0.0087604039905	0.428571428571	IQCB1 CEP97 CEP290	Ciliary landscape
GO:0120033	0.0135831041104	0.428571428571	KIF24 CEP97 CCP110	negative regulation of plasma membrane bounded cell projection assembly
GO:0120031	0.0154131050819	0.714285714286	CCP110 IQCB1 KIF24 CEP97 CEP290	plasma membrane bounded cell projection assembly
GO:0030031	0.017418204933	0.714285714286	CCP110 IQCB1 KIF24 CEP97 CEP290	cell projection assembly
REAC:R-HSA-9013424	0.0225049419259	0.285714285714	CEP97 CCP110	RHOV GTPase cycle
GO:1902116	0.0281770340738	0.428571428571	KIF24 CEP97 CCP110	negative regulation of organelle assembly
GO:0015630	0.0362273678325	0.857142857143	CCDC61 CCP110 IQCB1 KIF24 CEP290 CEP97	microtubule cytoskeleton
WP:WP5234	0.0499136541057	0.285714285714	CEP290 IQCB1	Bardet Biedl syndrome

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
CCP110	CEP97	0.996	0.234602739726	hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM gupta () boldt_WMM
CCP110	IQCB1	0.995	0.256	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM
CCP110	CEP290	0.993	0.189529204785	hein_WMM bioplex_WMM bioplex3_WMM gupta () boldt hein () gupta_WMM boldt_WMM
KIF24	CEP97	0.992		hein_WMM bioplex3_HEK293 bioplex3_WMM hein () boldt_WMM
IQCB1	CEP97	0.99	0.188	hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only
IQCB1	CEP290	0.987	0.228	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta () boldt hein () gupta_WMM boldt_WMM
CCP110	PHLDB3	0.961	0.18	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
CEP290	CEP97	0.96	0.172	hein_WMM bioplex_WMM bioplex3_WMM gupta () hein () gupta_WMM boldt_WMM
CEP290	CCDC61	0.959	0.312816326531	hein_WMM gupta_WMM gupta () WMM_only
CCP110	KIF24	0.921		hein_WMM bioplex3_HEK293 bioplex3_WMM boldt_WMM WMM_only
CCP110	CCDC61	0.439	0.188	hein_WMM gupta_WMM WMM_only
PHLDB3	IQCB1	0.36	0.13	bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only
PHLDB3	CEP97	0.121	0.114	bioplex_WMM bioplex3_WMM WMM_only
CCDC61	CEP97	0.093	0.140361581921	hein_WMM gupta_WMM WMM_only
PHLDB3	CEP290	0.049	0.489113636364	bioplex3_WMM WMM_only
IQCB1	CCDC61	0.01	0.166	gupta_WMM WMM_only

Related Complexes

Genename	Complexes
CCDC61	huMAP3_02266.1 huMAP3_06255.1 huMAP3_07800.1 huMAP3_08899.1 huMAP3_09013.1 huMAP3_10089.1 huMAP3_11221.1
CEP97	huMAP3_05169.1 huMAP3_06653.1 huMAP3_10089.1 huMAP3_10597.1
CEP290	huMAP3_01980.1 huMAP3_02266.1 huMAP3_08899.1 huMAP3_09013.1 huMAP3_10089.1 huMAP3_10597.1 huMAP3_11221.1 huMAP3_14902.1
CCP110	huMAP3_01119.1 huMAP3_01980.1 huMAP3_02345.1 huMAP3_06653.1 huMAP3_07800.1 huMAP3_07908.1 huMAP3_09013.1 huMAP3_10089.1 huMAP3_10597.1 huMAP3_14902.1
IQCB1	huMAP3_01980.1 huMAP3_02345.1 huMAP3_06653.1 huMAP3_08899.1 huMAP3_10089.1 huMAP3_10597.1
PHLDB3	huMAP3_01980.1 huMAP3_02345.1 huMAP3_02540.1 huMAP3_03616.1 huMAP3_07908.1 huMAP3_08276.1 huMAP3_09286.1 huMAP3_10001.1 huMAP3_10089.1 huMAP3_10597.1 huMAP3_13836.1
KIF24	huMAP3_04015.1 huMAP3_05169.1 huMAP3_06653.1 huMAP3_07210.1 huMAP3_10089.1 huMAP3_10597.1 huMAP3_13259.1 huMAP3_13913.1 huMAP3_14779.1 huMAP3_14854.1 huMAP3_14902.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10089.1