hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10093.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TWIST2 | Twist-related protein 2 (Class A basic helix-loop-helix protein 39) (bHLHa39) (Dermis-expressed protein 1) (Dermo-1) | 5 | UniProt NCBI |
| MECOM | Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein homolog) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein) (Myelodysplasia syndrome-associated protein 1) | 5 | UniProt NCBI |
| HMGB2 | High mobility group protein B2 (High mobility group protein 2) (HMG-2) | 5 | UniProt NCBI |
| ZBTB20 | Zinc finger and BTB domain-containing protein 20 (Dendritic-derived BTB/POZ zinc finger protein) (Zinc finger protein 288) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0400653 | 0.00766824235305 | 0.5 | MECOM HMGB2 | rectum; fibroblasts[High] |
| HPA:0570772 | 0.0098768954175 | 0.75 | ZBTB20 MECOM HMGB2 | testis; peritubular cells[>=Medium] |
| HP:0002550 | 0.0145105245688 | 0.5 | ZBTB20 TWIST2 | Absent facial hair |
| HPA:0030443 | 0.0169204816204 | 0.5 | MECOM HMGB2 | appendix; non-germinal center cells[High] |
| HPA:0400203 | 0.0169204816204 | 0.5 | MECOM HMGB2 | rectum; endothelial cells[High] |
| HPA:0400243 | 0.0201031834303 | 0.5 | MECOM HMGB2 | rectum; peripheral nerve/ganglion[High] |
| HPA:0400652 | 0.0222302580139 | 0.5 | MECOM HMGB2 | rectum; fibroblasts[>=Medium] |
| HPA:0570771 | 0.0241544629227 | 0.75 | ZBTB20 MECOM HMGB2 | testis; peritubular cells[>=Low] |
| HPA:0400651 | 0.0272823440391 | 0.5 | MECOM HMGB2 | rectum; fibroblasts[>=Low] |
| HP:0002298 | 0.0375654511359 | 0.5 | ZBTB20 TWIST2 | Absent hair |
| HPA:0481353 | 0.0394949882091 | 0.5 | MECOM HMGB2 | small intestine; paneth cells[High] |
| HPA:0131333 | 0.0406620510762 | 0.5 | MECOM HMGB2 | colon; mucosal lymphoid cells[High] |
| HPA:0130203 | 0.0429017544915 | 0.75 | ZBTB20 MECOM HMGB2 | colon; endothelial cells[High] |
| HPA:0151353 | 0.0442638380554 | 0.5 | MECOM HMGB2 | duodenum; paneth cells[High] |
| HPA:0030893 | 0.0467487673522 | 0.5 | MECOM HMGB2 | appendix; goblet cells[High] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TWIST2 | ZBTB20 | 0.982 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MECOM | ZBTB20 | 0.974 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HMGB2 | ZBTB20 | 0.96 | 0.07 | hein_WMM bioplex3_WMM WMM_only |
| HMGB2 | TWIST2 | 0.01 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HMGB2 | MECOM | 0.002 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes