hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10094.1
Complex Portal: CPX-17806
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZNF536 | Zinc finger protein 536 | 4 | UniProt NCBI |
| LCORL | Ligand-dependent nuclear receptor corepressor-like protein (LCoR-like protein) | 4 | UniProt NCBI |
| UBALD2 | UBA-like domain-containing protein 2 | 2 | UniProt NCBI |
| ZNF516 | Zinc finger protein 516 | 5 | UniProt NCBI |
| RREB1 | Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1) | 5 | UniProt NCBI |
| ZEB2 | Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (SMADIP1) (Zinc finger homeobox protein 1b) | 5 | UniProt NCBI |
| ZNF217 | Zinc finger protein 217 | 5 | UniProt NCBI |
| CTBP1 | C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:642 | 5.68224555143e-12 | 0.625 | ZEB2 CTBP1 ZNF516 ZNF217 RREB1 | CtBP complex |
| CORUM:626 | 2.80202851888e-06 | 0.375 | ZNF217 RREB1 CTBP1 | LSD1 complex |
| CORUM:1492 | 0.00107416462378 | 0.25 | ZNF217 ZNF516 | BHC110 complex |
| HP:0001166 | 0.0205674938424 | 0.375 | ZEB2 RREB1 CTBP1 | Arachnodactyly |
| HP:0001238 | 0.0367737328953 | 0.375 | ZEB2 RREB1 CTBP1 | Slender finger |
| HP:0009918 | 0.0427341718023 | 0.25 | ZEB2 CTBP1 | Ectopia pupillae |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF516 | CTBP1 | 0.998 | 0.188 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| CTBP1 | ZNF217 | 0.985 | 0.078 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () | |
| LCORL | CTBP1 | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CTBP1 | RREB1 | 0.983 | 0.152 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| ZNF516 | ZNF217 | 0.975 | 0.112 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZNF536 | CTBP1 | 0.973 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | ||
| UBALD2 | ZNF217 | 0.965 | 0.044 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ZEB2 | CTBP1 | 0.956 | 0.108 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| ZNF516 | RREB1 | 0.942 | 0.08 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZNF217 | RREB1 | 0.937 | 0.09 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZNF536 | LCORL | 0.612 | 0.03 | bioplex_WMM bioplex3_WMM WMM_only | |
| LCORL | ZNF516 | 0.594 | 0.134 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF536 | ZEB2 | 0.587 | 0.116 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZEB2 | RREB1 | 0.57 | 0.052 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| LCORL | ZEB2 | 0.568 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZEB2 | ZNF217 | 0.538 | 0.09 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZNF536 | RREB1 | 0.505 | 0.07 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZNF516 | ZEB2 | 0.417 | 0.174 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| LCORL | RREB1 | 0.378 | 0.094 | bioplex_WMM bioplex3_WMM WMM_only | |
| LCORL | ZNF217 | 0.378 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF536 | ZNF217 | 0.341 | 0.096 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZNF536 | ZNF516 | 0.303 | 0.048 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes