hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10107.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GABPB1 | GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2) (Nuclear respiratory factor 2) (Transcription factor E4TF1-47) (Transcription factor E4TF1-53) | 5 | UniProt NCBI |
| TPD52L2 | Tumor protein D54 (hD54) (Tumor protein D52-like 2) | 5 | UniProt NCBI |
| TPD52L1 | Tumor protein D53 (hD53) (Tumor protein D52-like 1) | 5 | UniProt NCBI |
| GABPA | GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60) | 5 | UniProt NCBI |
| GRIN3B | Glutamate receptor ionotropic, NMDA 3B (GluN3B) (N-methyl-D-aspartate receptor subtype 3B) (NMDAR3B) (NR3B) | 5 | UniProt NCBI |
| TPD52 | Tumor protein D52 (Protein N8) | 5 | UniProt NCBI |
| GRIN3A | Glutamate receptor ionotropic, NMDA 3A (GluN3A) (N-methyl-D-aspartate receptor subtype 3A) (NMDAR3A) (NR3A) (NMDAR-L) | 5 | UniProt NCBI |
| TPD52L3 | Tumor protein D55 (hD55) (Testis development protein NYD-SP25) (Tumor protein D52-like 3) | 3 | UniProt NCBI |
| CHD6 | Chromodomain-helicase-DNA-binding protein 6 (CHD-6) (EC 3.6.4.12) (ATP-dependent helicase CHD6) (Radiation-induced gene B protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5398 | 0.00278824374686 | 0.222222222222 | GRIN3B GRIN3A | NRXN1 deletion syndrome |
| KEGG:05033 | 0.0046708432359 | 0.222222222222 | GRIN3B GRIN3A | Nicotine addiction |
| WP:WP391 | 0.00468193988771 | 0.222222222222 | GABPB1 GABPA | Mitochondrial gene expression |
| WP:WP3657 | 0.0052310849594 | 0.222222222222 | GABPB1 GABPA | Hematopoietic stem cell gene regulation by GABP alpha beta complex |
| KEGG:05030 | 0.0138019713376 | 0.222222222222 | GRIN3B GRIN3A | Cocaine addiction |
| KEGG:05031 | 0.0267263448961 | 0.222222222222 | GRIN3B GRIN3A | Amphetamine addiction |
| WP:WP4539 | 0.0287089830042 | 0.222222222222 | GRIN3B GRIN3A | Synaptic signaling pathways associated with autism spectrum disorder |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GABPB1 | GABPA | 1.0 | 0.49 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM Malo bioplex3_HCT116 fraction |
| TPD52L2 | TPD52L1 | 0.999 | 0.17 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| TPD52L3 | GABPB1 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TPD52L2 | TPD52 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction | |
| GABPB1 | TPD52L2 | 0.998 | 0.066 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TPD52L3 | TPD52 | 0.997 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TPD52L3 | GABPA | 0.997 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TPD52L1 | TPD52 | 0.996 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| TPD52L3 | TPD52L1 | 0.994 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TPD52L3 | TPD52L2 | 0.994 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TPD52L1 | GRIN3B | 0.993 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TPD52 | GRIN3B | 0.991 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GRIN3B | GRIN3A | 0.987 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| TPD52 | CHD6 | 0.971 | bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| TPD52L2 | GRIN3B | 0.96 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GABPA | TPD52L2 | 0.952 | 0.0406666666667 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM boldt_WMM |
| GABPA | TPD52L1 | 0.455 | 0.028 | bioplex3_WMM WMM_only |
| GABPB1 | TPD52L1 | 0.412 | 0.052 | bioplex3_WMM WMM_only |
| TPD52L1 | CHD6 | 0.401 | 0.08 | bioplex3_WMM WMM_only |
| GABPB1 | TPD52 | 0.293 | bioplex3_WMM WMM_only | |
| TPD52L1 | GRIN3A | 0.278 | bioplex3_WMM WMM_only | |
| TPD52 | GRIN3A | 0.21 | bioplex3_WMM WMM_only | |
| GABPA | TPD52 | 0.132 | bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| TPD52L2 | CHD6 | 0.096 | 0.108 | bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| TPD52L2 | GRIN3A | 0.093 | bioplex3_WMM WMM_only | |
| GABPA | CHD6 | 0.016 | 0.074 | youn_WMM gupta_WMM WMM_only |
Related Complexes