hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10117.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BTG2 | Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3) | 5 | UniProt NCBI |
| BTG1 | Protein BTG1 (B-cell translocation gene 1 protein) | 5 | UniProt NCBI |
| PABPN1L | Embryonic polyadenylate-binding protein 2 (Embryonic poly(A)-binding protein 2) (ePABP-2) (ePABP2) (Embryonic poly(A)-binding protein type II) (Poly(A)-binding protein nuclear-like 1) | 3 | UniProt NCBI |
| CNOT7 | CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a) | 5 | UniProt NCBI |
| GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta (Myeloid differentiation primary response protein MyD118) (Negative growth regulatory protein MyD118) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03018 | 5.76252819292e-05 | 0.6 | CNOT7 BTG2 BTG1 | RNA degradation |
| REAC:R-HSA-6804115 | 0.00232071308473 | 0.4 | CNOT7 BTG2 | TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain |
| REAC:R-HSA-6791312 | 0.0149609318958 | 0.4 | CNOT7 BTG2 | TP53 Regulates Transcription of Cell Cycle Genes |
| GO:0000288 | 0.036132773595 | 0.6 | CNOT7 BTG2 PABPN1L | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CNOT7 | BTG2 | 0.996 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CNOT7 | PABPN1L | 0.992 | 0.088 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| CNOT7 | BTG1 | 0.992 | 0.062 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CNOT7 | GADD45B | 0.964 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| BTG2 | BTG1 | 0.606 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes