hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10132.1
Complex Portal: CPX-18043
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PNOC | Prepronociceptin [Cleaved into: Nocistatin; Nociceptin (Orphanin FQ) (PPNOC); Orphanin FQ2] | 5 | UniProt NCBI |
| WDFY2 | WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2) (Zinc finger FYVE domain-containing protein 22) | 5 | UniProt NCBI |
| MIEF1 | Mitochondrial dynamics protein MIEF1 (Mitochondrial dynamics protein of 51 kDa) (Mitochondrial elongation factor 1) (Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like) (SMCR7-like protein) | 5 | UniProt NCBI |
| MAOA | Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5579012 | 0.0499436884912 | 0.25 | MAOA | Defective MAOA causes BRUNS |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MIEF1 | MAOA | 0.991 | 0.034 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| WDFY2 | PNOC | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| WDFY2 | MIEF1 | 0.987 | 0.09 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| PNOC | huMAP3_00830.1 huMAP3_06343.1 huMAP3_10132.1 |
| WDFY2 | huMAP3_00830.1 huMAP3_05905.1 huMAP3_06492.1 huMAP3_10132.1 |
| MIEF1 | huMAP3_01228.1 huMAP3_05905.1 huMAP3_06492.1 huMAP3_10132.1 |
| MAOA | huMAP3_01228.1 huMAP3_05905.1 huMAP3_06867.1 huMAP3_10132.1 |