hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10142.1
Complex Portal: CPX-12314
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CFAP36 | Cilia- and flagella-associated protein 36 (Coiled-coil domain-containing protein 104) | 5 | UniProt NCBI |
| ARL3 | ADP-ribosylation factor-like protein 3 | 5 | UniProt NCBI |
| ARL2BP | ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein) (ARL2-binding protein) (Binder of ARF2 protein 1) | 5 | UniProt NCBI |
| PTPDC1 | Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-) | 4 | UniProt NCBI |
| ARL2 | ADP-ribosylation factor-like protein 2 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-83936 | 0.000546723465219 | 0.4 | ARL2 ARL2BP | Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane |
| REAC:R-HSA-425397 | 0.00750894366662 | 0.4 | ARL2 ARL2BP | Transport of vitamins, nucleosides, and related molecules |
| HP:0000510 | 0.0140788593896 | 0.6 | ARL3 ARL2BP ARL2 | Rod-cone dystrophy |
| WP:WP4656 | 0.0144790152013 | 0.4 | ARL3 ARL2 | Joubert syndrome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CFAP36 | ARL2 | 0.999 | 0.036 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ARL2 | ARL2BP | 0.995 | 0.006 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only |
| ARL3 | ARL2BP | 0.99 | 0.038 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | |
| PTPDC1 | ARL2 | 0.968 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM | |
| ARL3 | CFAP36 | 0.847 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PTPDC1 | CFAP36 | 0.415 |
mutually_exclusive (P36404)
|
bioplex3_WMM WMM_only | |
| ARL3 | ARL2 | 0.353 | 0.062 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only | |
| CFAP36 | ARL2BP | 0.274 | 0.072 | bioplex3_WMM WMM_only | |
| PTPDC1 | ARL2BP | 0.095 |
mutually_exclusive (P36404)
|
bioplex3_WMM WMM_only |
Related Complexes