hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10145.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HSD11B1 | 11-beta-hydroxysteroid dehydrogenase 1 (11-DH) (11-beta-HSD1) (EC 1.1.1.146) (7-oxosteroid reductase) (EC 1.1.1.201) (Corticosteroid 11-beta-dehydrogenase isozyme 1) (Short chain dehydrogenase/reductase family 26C member 1) | 5 | UniProt NCBI |
| NMNAT2 | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 (NMN/NaMN adenylyltransferase 2) (EC 2.7.7.1) (EC 2.7.7.18) (Nicotinamide mononucleotide adenylyltransferase 2) (NMN adenylyltransferase 2) (Nicotinate-nucleotide adenylyltransferase 2) (NaMN adenylyltransferase 2) | 5 | UniProt NCBI |
| SURF1 | Surfeit locus protein 1 | 5 | UniProt NCBI |
| HYAL1 | Hyaluronidase-1 (Hyal-1) (EC 3.2.1.35) (Hyaluronoglucosaminidase-1) (Lung carcinoma protein 1) (LuCa-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2206280 | 0.0498224659464 | 0.333333333333 | HYAL1 | MPS IX - Natowicz syndrome |
| CORUM:6402 | 0.0499402709677 | 0.333333333333 | NMNAT2 | NMNAT2-HSP90 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HSD11B1 | SURF1 | 0.982 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SURF1 | NMNAT2 | 0.982 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SURF1 | HYAL1 | 0.979 | bioplex3_WMM bioplex3_HCT116 WMM_only |
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