hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10148.1

Complex Portal: CPX-22176

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
PPP1R8	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)]	5	UniProt NCBI
CSRNP1	Cysteine/serine-rich nuclear protein 1 (CSRNP-1) (Axin-1 up-regulated gene 1 protein) (Protein URAX1) (TGF-beta-induced apoptosis protein 3) (TAIP-3)	5	UniProt NCBI
PPP1R11	E3 ubiquitin-protein ligase PPP1R11 (EC 2.3.2.27) (Hemochromatosis candidate gene V protein) (HCG V) (Protein phosphatase 1 regulatory subunit 11) (Protein phosphatase inhibitor 3)	5	UniProt NCBI
CCDC85C	Coiled-coil domain-containing protein 85C	3	UniProt NCBI
PPP1R2	Protein phosphatase inhibitor 2 (IPP-2)	5	UniProt NCBI
PPP1R13B	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)	5	UniProt NCBI
PPP1R18	Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18)	5	UniProt NCBI
RASSF8	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1)	4	UniProt NCBI
LMTK2	Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)	5	UniProt NCBI
PPP1R7	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)	5	UniProt NCBI
KIF18A	Kinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A)	5	UniProt NCBI
FRMD6	FERM domain-containing protein 6 (Willin)	5	UniProt NCBI
C2orf74	Uncharacterized protein C2orf74	2	UniProt NCBI
CSRNP3	Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2)	4	UniProt NCBI
TANC2	Protein TANC2 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2)	5	UniProt NCBI
PPP1CC	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)	5	UniProt NCBI
RASIP1	Ras-interacting protein 1 (Rain)	5	UniProt NCBI
ZFYVE9	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)	5	UniProt NCBI
PLCL2	Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2)	5	UniProt NCBI
C12orf57	Protein C10	5	UniProt NCBI
CSRNP2	Cysteine/serine-rich nuclear protein 2 (CSRNP-2) (Protein FAM130A1) (TGF-beta-induced apoptosis protein 12) (TAIP-12)	4	UniProt NCBI
CCDC85B	Coiled-coil domain-containing protein 85B (Hepatitis delta antigen-interacting protein A) (Delta-interacting protein A)	5	UniProt NCBI
RASSF7	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1)	5	UniProt NCBI
PPP1CB	Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)	5	UniProt NCBI
PPP1R37	Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68)	5	UniProt NCBI
CNST	Consortin	5	UniProt NCBI
PPP1R13L	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein)	5	UniProt NCBI
ZFYVE16	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein)	5	UniProt NCBI
PPP1CA	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)	5	UniProt NCBI
TP53BP2	Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)	5	UniProt NCBI
SH2D4A	SH2 domain-containing protein 4A (Protein SH(2)A) (Protein phosphatase 1 regulatory subunit 38)	5	UniProt NCBI
SHOC2	Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog)	5	UniProt NCBI
GABBR1	Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP4861	2.59685718167e-12	0.242424242424	PPP1CB PPP1R7 PPP1R13B PPP1R2 PPP1R11 PPP1CC PPP1R8 PPP1CA	Endoplasmic reticulum stress response in coronavirus infection
REAC:R-HSA-9660537	0.000196910405932	0.0909090909091	PPP1CC SHOC2 PPP1CB	Signaling by MRAS-complex mutants
REAC:R-HSA-9726840	0.000196910405932	0.0909090909091	PPP1CC SHOC2 PPP1CB	SHOC2 M1731 mutant abolishes MRAS complex function
REAC:R-HSA-9726842	0.000196910405932	0.0909090909091	PPP1CC SHOC2 PPP1CB	Gain-of-function MRAS complexes activate RAF signaling
GO:0019888	0.000230374721743	0.181818181818	PPP1R7 LMTK2 SHOC2 PPP1R2 PPP1R11 PPP1R8	protein phosphatase regulator activity
GO:0019208	0.000576278643276	0.181818181818	PPP1R7 LMTK2 SHOC2 PPP1R2 PPP1R11 PPP1R8	phosphatase regulator activity
REAC:R-HSA-6804759	0.000577507196683	0.0909090909091	PPP1R13B PPP1R13L TP53BP2	Regulation of TP53 Activity through Association with Co-factors
CORUM:7423	0.000767732857776	0.0606060606061	PPP1CA PPP1R13L	PPP1CA-PPP1R13L complex
KEGG:04390	0.00108483994325	0.151515151515	PPP1CC TP53BP2 FRMD6 PPP1CA PPP1CB	Hippo signaling pathway
GO:0000164	0.00192260484373	0.121212121212	PPP1CC SHOC2 PPP1CA PPP1CB	protein phosphatase type 1 complex
REAC:R-HSA-163560	0.00393512482821	0.0909090909091	PPP1CC PPP1CA PPP1CB	Triglyceride catabolism
REAC:R-HSA-2173788	0.00608507891172	0.0909090909091	PPP1CC PPP1CA PPP1CB	Downregulation of TGF-beta receptor signaling
GO:0004864	0.0062723828096	0.121212121212	PPP1R8 LMTK2 PPP1R2 PPP1R11	protein phosphatase inhibitor activity
WP:WP2636	0.00654622917586	0.0909090909091	PPP1CC PPP1CA PPP1CB	Common pathways underlying drug addiction
GO:0019212	0.0131734295792	0.121212121212	PPP1R8 LMTK2 PPP1R2 PPP1R11	phosphatase inhibitor activity
REAC:R-HSA-5673000	0.0138004788115	0.0909090909091	PPP1CC SHOC2 PPP1CB	RAF activation
KEGG:04720	0.0148285617246	0.0909090909091	PPP1CC PPP1CA PPP1CB	Long-term potentiation
REAC:R-HSA-8979227	0.0168078857218	0.0909090909091	PPP1CC PPP1CA PPP1CB	Triglyceride metabolism
KEGG:05031	0.0174120153203	0.0909090909091	PPP1CC PPP1CA PPP1CB	Amphetamine addiction
GO:0072357	0.0182422971773	0.0909090909091	PPP1CC PPP1CA PPP1CB	PTW/PP1 phosphatase complex
KEGG:04024	0.0259830058091	0.121212121212	PPP1CC GABBR1 PPP1CA PPP1CB	cAMP signaling pathway
KEGG:04750	0.0306089912448	0.0909090909091	PPP1CC PPP1CA PPP1CB	Inflammatory mediator regulation of TRP channels
REAC:R-HSA-9006936	0.0330516981979	0.121212121212	PPP1CC ZFYVE16 PPP1CA PPP1CB	Signaling by TGFB family members
REAC:R-HSA-2173789	0.0356266565993	0.0909090909091	PPP1CC PPP1CA PPP1CB	TGF-beta receptor signaling activates SMADs

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
PPP1CB	PPP1CC	1.0	0.598	structurally_consistent (dimer)
PPP1R7	PPP1CC	1.0	0.227454545455
RASSF8	TP53BP2	1.0	0.148
PPP1CA	PPP1CC	1.0	0.694	mutually_exclusive (P41236) structurally_consistent (dimer)
PPP1R13B	RASSF8	1.0	0.112
PPP1R7	PPP1R11	1.0	0.096
PPP1R2	PPP1CC	1.0	0.232	structurally_consistent (dimer)
PPP1R13B	PPP1CC	1.0	0.118
PPP1CB	PPP1R18	1.0	0.212	structurally_consistent (dimer)
CNST	PPP1CC	1.0	0.198
RASSF7	TP53BP2	1.0	0.088	mutually_exclusive (P62140)
TANC2	PPP1CC	1.0	0.272
PPP1CB	PPP1CA	1.0	0.556	mutually_exclusive (Q9H788) structurally_consistent (dimer)
PPP1R8	PPP1CC	0.999	0.262
ZFYVE16	PPP1CC	0.999	0.07
RASSF7	PPP1R13B	0.999	0.09	mutually_exclusive (P62140)
PPP1CA	PPP1R18	0.999	0.17	mutually_exclusive (P62140) structurally_consistent (dimer)
PPP1CC	PPP1R18	0.999	0.1112
TP53BP2	PPP1CC	0.999	0.065
PPP1CC	KIF18A	0.999	0.296
ZFYVE9	PPP1CC	0.999	0.154
PPP1CC	PPP1R13L	0.999	0.144
PPP1CA	PPP1R8	0.999	0.222	mutually_exclusive (P62140) structurally_consistent (dimer)
PPP1CA	PPP1R7	0.999	0.34	structurally_consistent (dimer)
PPP1CA	PPP1R13L	0.999	0.172	mutually_exclusive (P62140) structurally_consistent (dimer)
RASSF7	PPP1CC	0.998	0.23
CCDC85C	PPP1CC	0.998	0.211	structurally_consistent (P62136)
C12orf57	PPP1CA	0.998	0.024	structurally_consistent (dimer)
TANC2	PPP1CA	0.997	0.19
PPP1R13B	TP53BP2	0.997	0.11
PPP1CC	LMTK2	0.997	0.146
PPP1CB	PPP1R7	0.996	0.266	mutually_exclusive (Q9GZN8) structurally_consistent (dimer)
PPP1R11	PPP1CC	0.996	0.116	structurally_consistent (P62136)
PPP1CA	TP53BP2	0.996	0.064	structurally_consistent (dimer)
SH2D4A	PPP1R7	0.996	0.026	mutually_exclusive (P62136)
PPP1R13B	PPP1CA	0.995	0.136571428571	structurally_consistent (dimer)
PPP1CA	ZFYVE16	0.995	0.086	structurally_consistent (dimer)
PPP1R13B	CCDC85C	0.995	0.138
CCDC85C	PPP1CA	0.995	0.327276099629	mutually_exclusive (P62140) structurally_consistent (dimer)
PPP1CB	PPP1R13L	0.995	0.232	mutually_exclusive (P62136) structurally_consistent (dimer)
PPP1CB	SH2D4A	0.995	0.138	structurally_consistent (dimer)
PPP1CA	ZFYVE9	0.994	0.236	structurally_consistent (dimer)
PPP1CA	KIF18A	0.993	0.488	structurally_consistent (dimer)
PPP1CA	CNST	0.993	0.146	structurally_consistent (dimer)
RASIP1	PPP1R18	0.992	0.064
PPP1CB	TANC2	0.992	0.27
CSRNP2	PPP1CC	0.992
CCDC85B	PPP1R13B	0.992	0.124
C12orf57	TANC2	0.992	0.05
CSRNP1	PPP1CA	0.991		mutually_exclusive (P62140) structurally_consistent (dimer)
PPP1CB	PPP1R13B	0.99	0.132	structurally_consistent (dimer)
PPP1CA	SHOC2	0.988	0.144	structurally_consistent (dimer)
GABBR1	PPP1R13L	0.988
RASSF7	PPP1CA	0.988	0.138
C12orf57	PPP1CC	0.987	0.088	structurally_consistent (P62136)
PPP1R2	PPP1CB	0.986	0.172	structurally_consistent (dimer)
PPP1CB	PPP1R8	0.985	0.22	mutually_exclusive (P62136) structurally_consistent (dimer)
RASSF8	FRMD6	0.985	0.156
SHOC2	PPP1CC	0.984	0.414	mutually_exclusive (P62140) structurally_consistent (dimer)
PPP1CA	SH2D4A	0.983	0.112	structurally_consistent (dimer)
RASSF8	PPP1CC	0.982	0.144
PPP1R2	PPP1CA	0.982	0.204	mutually_exclusive (P62140) structurally_consistent (dimer)
PPP1R2	PPP1R7	0.981	0.128
PPP1R13B	CNST	0.98	0.07	mutually_exclusive (P62136)
PPP1CA	PLCL2	0.979	0.332	structurally_consistent (dimer)
PPP1CA	CSRNP2	0.978		mutually_exclusive (P62140) structurally_consistent (dimer)
CCDC85B	PPP1CA	0.978	0.1412
CSRNP3	PPP1CC	0.976
CCDC85B	PPP1CC	0.976	0.188
PPP1R7	PPP1R18	0.975	0.03	mutually_exclusive (P62136)
PPP1R7	PPP1R13L	0.974	0.018	mutually_exclusive (P62136)
TANC2	PPP1R13L	0.974	0.078
C2orf74	PPP1CA	0.973		structurally_consistent (dimer)
PLCL2	PPP1CC	0.972	0.198
CCDC85B	CCDC85C	0.972	0.108
RASSF7	PPP1R18	0.972	0.042	mutually_exclusive (P62140)
PPP1R11	PPP1R18	0.969	0.056	mutually_exclusive (P62136)
PPP1R13B	PPP1R7	0.968	0.098	mutually_exclusive (P62140)
CNST	PPP1R18	0.968	0.086	mutually_exclusive (P62136)
PPP1R8	LMTK2	0.967	0.094
PPP1CA	PPP1R11	0.967	0.214	mutually_exclusive (P62140) structurally_consistent (dimer)
TANC2	TP53BP2	0.966	0.064
PPP1CA	RASSF8	0.964	0.27	structurally_consistent (dimer)
PPP1R11	CNST	0.964	0.19
CSRNP1	PPP1CC	0.963
LMTK2	PPP1R18	0.962	0.058
CCDC85C	ZFYVE16	0.962	0.068	mutually_exclusive (P62136)
CNST	ZFYVE16	0.962	0.044	mutually_exclusive (P62136)
ZFYVE16	PPP1R18	0.962	0.028	mutually_exclusive (P62136)
RASSF7	PPP1R11	0.962	0.052	mutually_exclusive (P62140)
C12orf57	ZFYVE9	0.961	0.048
RASSF7	CNST	0.961	0.102
ZFYVE16	KIF18A	0.959	0.07	mutually_exclusive (P62136)
PPP1R11	ZFYVE16	0.959	0.018	mutually_exclusive (P62136)
LMTK2	KIF18A	0.959	0.114
CNST	LMTK2	0.959	0.106
PPP1R11	LMTK2	0.959	0.056
TP53BP2	FRMD6	0.959	0.086
CSRNP1	PPP1CB	0.958		mutually_exclusive (P62136) structurally_consistent (dimer)
PPP1R37	PPP1CA	0.958	0.182	structurally_consistent (dimer)
ZFYVE16	LMTK2	0.956	0.09
PPP1R8	ZFYVE16	0.954	0.044	mutually_exclusive (P62136)
PPP1R2	PPP1R8	0.954	0.082
CCDC85C	PPP1R11	0.953	0.152
RASSF7	RASSF8	0.951	0.06
CCDC85C	CNST	0.951	0.132
C12orf57	PPP1CB	0.949	0.046	structurally_consistent (P62136)
PPP1CB	PPP1R11	0.949	0.128	structurally_consistent (dimer)
ZFYVE9	ZFYVE16	0.947	0.096
RASSF7	PPP1CB	0.941	0.116	structurally_consistent (dimer)
CCDC85C	LMTK2	0.941	0.148
ZFYVE9	PPP1R11	0.94	0.054	mutually_exclusive (P62140)
TP53BP2	PPP1R11	0.939	0.044	mutually_exclusive (P62136)
TANC2	LMTK2	0.936	0.074
RASSF7	LMTK2	0.936	0.12
ZFYVE9	LMTK2	0.936	0.102
TP53BP2	LMTK2	0.933	0.09
LMTK2	PPP1R13L	0.932	0.064
PPP1R2	PPP1R11	0.932	0.058
PPP1R2	LMTK2	0.932	0.082
C12orf57	PPP1R13L	0.931	0.016
CCDC85C	KIF18A	0.928	0.148
PPP1R11	KIF18A	0.927	0.106	mutually_exclusive (P62136)
ZFYVE9	KIF18A	0.926	0.094
PPP1R8	PPP1R18	0.924	0.026	mutually_exclusive (P62136)
CCDC85C	PPP1R18	0.923	0.04
RASSF7	KIF18A	0.922	0.09
PPP1R8	PPP1R11	0.921	0.03	mutually_exclusive (P62136)
PPP1R13B	LMTK2	0.921	0.084
TANC2	PPP1R18	0.92	0.03
KIF18A	PPP1R18	0.92	0.04	mutually_exclusive (P62136)
CNST	KIF18A	0.92	0.07	mutually_exclusive (P62136)
TP53BP2	KIF18A	0.918	0.218	mutually_exclusive (P62136)
CCDC85C	TP53BP2	0.917	0.072
PPP1CB	LMTK2	0.917	0.174
CNST	PPP1R13L	0.916	0.076	mutually_exclusive (P62136)
ZFYVE9	PPP1R18	0.916	0.018	mutually_exclusive (P62140)
PPP1R13B	PPP1R11	0.915	0.05
PPP1R8	CNST	0.914	0.092	mutually_exclusive (P62136)
PPP1R13B	PPP1R8	0.908	0.072
TP53BP2	ZFYVE16	0.907	0.102	mutually_exclusive (P62136)
PPP1R13B	PPP1R13L	0.906	0.062
RASSF7	TANC2	0.899	0.116
TANC2	PPP1R11	0.899	0.042
ZFYVE9	PPP1R8	0.898	0.132	mutually_exclusive (P62140)
PPP1R13B	KIF18A	0.897	0.118	mutually_exclusive (P62136)
ZFYVE9	PPP1R13L	0.897	0.032
ZFYVE9	CNST	0.894	0.084
RASSF7	ZFYVE9	0.892	0.086	mutually_exclusive (P62140)
PPP1R18	PPP1R13L	0.892	0.048	mutually_exclusive (P62136)
TANC2	CNST	0.885	0.032
PPP1R13B	ZFYVE9	0.88	0.136	mutually_exclusive (P62140)
C12orf57	ZFYVE16	0.879	0.036
PPP1R13B	PPP1R18	0.871	0.032
RASSF7	PPP1R13L	0.87	0.07	mutually_exclusive (P62140)
PPP1R7	LMTK2	0.87	0.108
TANC2	PPP1R13B	0.868	0.122
RASSF7	PPP1R8	0.867	0.046	mutually_exclusive (P62140)
ZFYVE9	TP53BP2	0.866	0.132	mutually_exclusive (P62140)
TP53BP2	CNST	0.866	0.134	mutually_exclusive (P62136)
TP53BP2	PPP1R18	0.851	0.044	mutually_exclusive (P62136)
ZFYVE16	PPP1R13L	0.85	0.048	mutually_exclusive (P62136)
RASSF7	ZFYVE16	0.846	0.108
SH2D4A	PPP1CC	0.841	0.108
RASSF7	CCDC85C	0.837	0.182	mutually_exclusive (P62140)
CCDC85C	ZFYVE9	0.837	0.066
TP53BP2	PPP1R8	0.835	0.032	mutually_exclusive (P62136)
PPP1R8	KIF18A	0.834	0.1	mutually_exclusive (P62136)
CSRNP2	PPP1R18	0.825
PPP1R2	PPP1R18	0.82	0.026
PPP1R2	CNST	0.82	0.066	mutually_exclusive (P62136)
TANC2	PPP1R7	0.818	0.062
CSRNP1	PPP1R7	0.816
SH2D4A	PPP1R11	0.809	0.034	mutually_exclusive (P62136)
TP53BP2	PPP1R13L	0.808	0.07	mutually_exclusive (P62136)
PPP1R11	PPP1R13L	0.805	0.044	mutually_exclusive (P62136)
TANC2	KIF18A	0.803	0.198
PPP1CB	KIF18A	0.799	0.442
TANC2	ZFYVE9	0.796	0.052
PPP1CB	CNST	0.789	0.126
SH2D4A	PPP1R13L	0.786	0.052	mutually_exclusive (P62136)
KIF18A	PPP1R13L	0.78	0.076	mutually_exclusive (P62136)
TANC2	PPP1R8	0.779	0.036
TANC2	ZFYVE16	0.778	0.038
PPP1R13B	ZFYVE16	0.774	0.244	mutually_exclusive (P62136)
SH2D4A	KIF18A	0.765	0.13	mutually_exclusive (P62136)
PPP1R2	TANC2	0.764	0.04
TANC2	RASSF8	0.75	0.13
CCDC85C	PPP1R13L	0.747	0.064
PPP1R2	RASSF7	0.744	0.092	mutually_exclusive (P62140)
TANC2	CCDC85C	0.743	0.062
PLCL2	TP53BP2	0.74	0.114	mutually_exclusive (P62136)
CCDC85B	KIF18A	0.74	0.138
RASSF7	PPP1R7	0.739	0.084	mutually_exclusive (P62140)
CSRNP2	PPP1R11	0.737
PPP1CB	PLCL2	0.737	0.246
PPP1R2	ZFYVE16	0.729	0.026	mutually_exclusive (P62136)
CCDC85B	PPP1R8	0.723	0.08
PPP1CB	ZFYVE9	0.71	0.283090909091	structurally_consistent (dimer)
PPP1CB	ZFYVE16	0.705	0.176
CCDC85B	RASSF7	0.701	0.088
PPP1R7	ZFYVE16	0.699	0.056
PPP1R2	KIF18A	0.695	0.086	mutually_exclusive (P62136)
PLCL2	PPP1R11	0.685	0.036	mutually_exclusive (P62136)
PLCL2	KIF18A	0.685	0.102	mutually_exclusive (P62136)
PLCL2	PPP1R13L	0.685	0.064	mutually_exclusive (P62136)
PPP1R2	PPP1R13L	0.68	0.026
PPP1CB	TP53BP2	0.678	0.148	structurally_consistent (dimer)
C12orf57	PPP1R11	0.676	0.038	structurally_consistent (P62136)
C12orf57	RASSF7	0.676	0.064
C12orf57	CNST	0.676	0.028
C12orf57	PPP1R18	0.676	0.02
PPP1R7	PPP1R8	0.671	0.09
CCDC85B	PPP1R11	0.671	0.114
CCDC85C	PPP1R8	0.671	0.086
PPP1R8	PPP1R13L	0.668	0.012	mutually_exclusive (P62136)
ZFYVE9	CSRNP2	0.661
PPP1R8	CSRNP2	0.653
CSRNP2	KIF18A	0.653		mutually_exclusive (P62136)
CCDC85B	TP53BP2	0.653	0.114
PPP1CB	SHOC2	0.649	0.222	structurally_consistent (dimer)
PPP1CA	LMTK2	0.646	0.336
PPP1R7	KIF18A	0.634	0.078	mutually_exclusive (P62136)
CCDC85B	PPP1R13L	0.633	0.106
ZFYVE9	PPP1R7	0.629	0.094	mutually_exclusive (P62140)
CCDC85B	ZFYVE9	0.627	0.086
PPP1R2	CSRNP2	0.627
PPP1R37	KIF18A	0.62	0.07	mutually_exclusive (P62136)
PPP1R37	PPP1R11	0.62	0.098	mutually_exclusive (P62136)
CCDC85B	PPP1R7	0.61	0.028
RASSF8	PPP1R8	0.602	0.076
CCDC85B	SHOC2	0.602	0.146
CCDC85B	ZFYVE16	0.6	0.076
PPP1R7	CNST	0.593	0.064
RASSF7	PLCL2	0.589	0.082
PLCL2	PPP1R18	0.589	0.022	mutually_exclusive (P62136)
PPP1R13B	CSRNP2	0.589
SHOC2	RASSF8	0.589	0.108
PPP1R2	TP53BP2	0.587	0.098
SHOC2	PPP1R8	0.585	0.14
CSRNP1	CSRNP2	0.585
PPP1R37	CSRNP2	0.585		mutually_exclusive (P62136)
C2orf74	CSRNP2	0.582		mutually_exclusive (P62136)
C2orf74	CNST	0.582		mutually_exclusive (P62136)
C2orf74	ZFYVE16	0.582		mutually_exclusive (P62136)
C2orf74	PPP1R18	0.582		mutually_exclusive (P62136)
C2orf74	PPP1R11	0.582		mutually_exclusive (P62136)
CCDC85B	CSRNP2	0.58
PLCL2	RASSF8	0.58	0.068
CCDC85C	CSRNP2	0.58
PPP1R37	ZFYVE9	0.58	0.156	mutually_exclusive (P62136)
PPP1R37	PPP1R8	0.58	0.118	mutually_exclusive (P62136)
PPP1CB	RASSF8	0.576	0.198	structurally_consistent (dimer)
CSRNP2	ZFYVE16	0.575		mutually_exclusive (P62136)
SHOC2	CSRNP2	0.575
CSRNP2	CNST	0.575		mutually_exclusive (P62136)
CSRNP3	CNST	0.572
CSRNP2	CSRNP3	0.572
CSRNP3	ZFYVE16	0.572
CSRNP3	LMTK2	0.572
CSRNP3	PPP1R18	0.572
CSRNP3	PPP1R11	0.572
PPP1R37	PPP1R13L	0.572	0.06	mutually_exclusive (P62136)
PPP1R2	CCDC85C	0.57	0.064
CSRNP1	PPP1R37	0.57		mutually_exclusive (P62136)
C2orf74	PPP1R37	0.568		mutually_exclusive (P62136)
CSRNP1	C2orf74	0.568		mutually_exclusive (P62136)
PPP1R7	RASSF8	0.563	0.068
PPP1R2	CCDC85B	0.562	0.06
ZFYVE9	RASSF8	0.561	0.086
CCDC85B	PPP1CB	0.557	0.2
PPP1R13B	PLCL2	0.557	0.066	mutually_exclusive (P62136)
CCDC85B	CNST	0.557	0.114
PLCL2	ZFYVE16	0.555	0.038	mutually_exclusive (P62136)
SHOC2	ZFYVE16	0.555	0.024	mutually_exclusive (P62136)
RASSF7	SHOC2	0.555	0.086	mutually_exclusive (P62140)
SHOC2	PPP1R18	0.555	0.058	mutually_exclusive (P62136)
PLCL2	SHOC2	0.555	0.064	mutually_exclusive (P62136)
C2orf74	KIF18A	0.554		mutually_exclusive (P62136)
PPP1R2	SHOC2	0.547	0.066
PPP1CB	CCDC85C	0.546	0.23	structurally_consistent (dimer)
PPP1R13B	SHOC2	0.546	0.126
RASSF8	CNST	0.546	0.098
RASSF8	PPP1R18	0.546	0.076
SHOC2	KIF18A	0.545	0.148	mutually_exclusive (P62136)
CSRNP3	KIF18A	0.543
ZFYVE9	PLCL2	0.536	0.024
CCDC85B	PPP1R18	0.536	0.11
PLCL2	PPP1R7	0.526	0.044	structurally_consistent (P62136)
CCDC85C	PLCL2	0.526	0.072
C12orf57	PPP1R7	0.514	0.038	mutually_exclusive (P62136)
C2orf74	TANC2	0.513
CSRNP2	LMTK2	0.513
CSRNP1	CNST	0.513		mutually_exclusive (P62136)
C2orf74	PPP1R8	0.513		mutually_exclusive (P62136)
TANC2	PPP1R37	0.513	0.16
CSRNP1	PPP1R18	0.513
C2orf74	ZFYVE9	0.513
C2orf74	PLCL2	0.513		mutually_exclusive (P62136)
C2orf74	SHOC2	0.513		mutually_exclusive (P62136)
C2orf74	RASSF7	0.513
C2orf74	PPP1R13L	0.513		mutually_exclusive (P62136)
CSRNP1	ZFYVE16	0.513		mutually_exclusive (P62136)
PPP1R37	CNST	0.512	0.066	mutually_exclusive (P62136)
PPP1R37	PPP1R18	0.512	0.032	mutually_exclusive (P62136)
C12orf57	KIF18A	0.511	0.04	mutually_exclusive (P62136)
ZFYVE9	SHOC2	0.51	0.09	mutually_exclusive (P62140)
PLCL2	CNST	0.51	0.044	mutually_exclusive (P62136)
SHOC2	CNST	0.51	0.076	mutually_exclusive (P62136)
CSRNP1	KIF18A	0.506		mutually_exclusive (P62136)
CSRNP1	PPP1R11	0.506
PPP1R8	CSRNP3	0.502
ZFYVE9	CSRNP3	0.502
SHOC2	CSRNP3	0.502
TANC2	CSRNP3	0.502
PLCL2	CSRNP3	0.502
CSRNP3	PPP1R13L	0.502
RASSF7	CSRNP3	0.502
SHOC2	PPP1R11	0.501	0.072
PPP1R7	CSRNP2	0.499
SHOC2	TP53BP2	0.497	0.092	mutually_exclusive (P62136)
C12orf57	CCDC85C	0.492	0.064	structurally_consistent (P62136)
PPP1R2	RASSF8	0.492	0.066
CCDC85C	SH2D4A	0.489	0.08	mutually_exclusive (P62140)
C12orf57	PPP1R8	0.482	0.078	mutually_exclusive (P62136)
PLCL2	PPP1R8	0.48	0.038	mutually_exclusive (P62136)
PLCL2	CSRNP2	0.476		mutually_exclusive (P62136)
RASSF7	CSRNP2	0.476		mutually_exclusive (P62140)
TP53BP2	CSRNP2	0.475
PPP1CB	CSRNP2	0.475		mutually_exclusive (P62136) structurally_consistent (dimer)
RASSF8	KIF18A	0.475	0.138	mutually_exclusive (P62136)
RASSF7	PPP1R37	0.471	0.098
PPP1R37	SHOC2	0.471	0.096	mutually_exclusive (P62136)
CCDC85C	PPP1R7	0.465	0.068
PPP1R37	PLCL2	0.461	0.046	mutually_exclusive (P62136)
SH2D4A	TP53BP2	0.459	0.056	mutually_exclusive (P62136)
PPP1R2	ZFYVE9	0.446	0.114
PPP1R2	PLCL2	0.442	0.028	mutually_exclusive (P62136)
CSRNP2	PPP1R13L	0.44
C12orf57	PPP1R13B	0.437	0.072
PPP1R37	PPP1R13B	0.435	0.16	mutually_exclusive (P62136)
PPP1R7	TP53BP2	0.435	0.026	mutually_exclusive (P62136)
RASSF8	PPP1R11	0.431	0.092
PPP1R2	PPP1R13B	0.429	0.08
PPP1R2	C12orf57	0.414	0.042
CCDC85C	SHOC2	0.406	0.05
C12orf57	PLCL2	0.401	0.044	structurally_consistent (P62136)
C12orf57	CSRNP2	0.401
C12orf57	SHOC2	0.401	0.046	structurally_consistent (P62136)
RASSF8	CSRNP2	0.4
TANC2	PLCL2	0.4	0.082
SHOC2	PPP1R13L	0.396	0.02	mutually_exclusive (P62136)
CSRNP1	SHOC2	0.396
C2orf74	RASSF8	0.396
CSRNP1	PPP1R13L	0.392
C12orf57	TP53BP2	0.392	0.022
CSRNP1	PPP1R8	0.389
CSRNP1	ZFYVE9	0.38
RASSF8	PPP1R13L	0.379	0.068
C2orf74	PPP1R13B	0.378		mutually_exclusive (P62136)
SHOC2	LMTK2	0.378	0.102
CSRNP1	RASSF7	0.378		mutually_exclusive (P62140)
CSRNP1	PLCL2	0.378		mutually_exclusive (P62136)
CSRNP1	TANC2	0.377
TANC2	SHOC2	0.367	0.072
TANC2	CSRNP2	0.367
PPP1R2	C2orf74	0.364		mutually_exclusive (P62136)
C2orf74	PPP1CB	0.363
PPP1CB	RASIP1	0.363	0.176
CCDC85B	PPP1R37	0.36	0.094
C12orf57	LMTK2	0.356	0.026
CCDC85B	RASSF8	0.352	0.162
CCDC85B	PLCL2	0.352	0.06
RASSF8	CSRNP3	0.35
PPP1R2	SH2D4A	0.349	0.032
C2orf74	TP53BP2	0.348		mutually_exclusive (P62136)
PPP1R13B	CSRNP3	0.333
CCDC85B	TANC2	0.324	0.106
PPP1R37	PPP1R7	0.323	0.114	mutually_exclusive (P62136)
PPP1R2	CSRNP3	0.32
C12orf57	RASSF8	0.316	0.058
TP53BP2	CSRNP3	0.303
PPP1CB	CSRNP3	0.29
CSRNP1	PPP1R13B	0.289
CSRNP1	CCDC85B	0.27
CSRNP1	PPP1R2	0.27
PPP1R37	RASSF8	0.27	0.128	mutually_exclusive (P62136)
CCDC85C	RASSF8	0.264	0.14
RASSF8	ZFYVE16	0.26	0.064	mutually_exclusive (P62136)
PPP1CA	RASIP1	0.245	0.14
CSRNP1	CCDC85C	0.244
SHOC2	PPP1R7	0.241	0.11
TANC2	FRMD6	0.229	0.074
C2orf74	CCDC85B	0.224
CSRNP1	RASSF8	0.224
PLCL2	LMTK2	0.224	0.078
PPP1CC	RASIP1	0.215	0.11
C2orf74	PPP1CC	0.215
C12orf57	C2orf74	0.214
C12orf57	PPP1R37	0.205	0.084	structurally_consistent (P62136)
CSRNP1	C12orf57	0.205
CSRNP1	TP53BP2	0.205
PPP1R2	PPP1R37	0.2	0.096	mutually_exclusive (P62136)
C12orf57	CCDC85B	0.196	0.078
SH2D4A	PPP1R8	0.195	0.014	mutually_exclusive (P62136)
PPP1CA	CSRNP3	0.189
C2orf74	PPP1R7	0.188
RASSF8	LMTK2	0.188	0.1125
CCDC85B	LMTK2	0.188	0.194
PPP1R37	ZFYVE16	0.181	0.202	mutually_exclusive (P62136)
RASSF7	FRMD6	0.181	0.13
CCDC85B	CSRNP3	0.172
C2orf74	CCDC85C	0.17
PPP1CB	PPP1R37	0.162	0.138
PPP1R37	TP53BP2	0.158	0.098	mutually_exclusive (P62136)
PPP1R37	CCDC85C	0.152	0.108	mutually_exclusive (P62136)
PPP1R13B	FRMD6	0.146	0.066
PPP1R7	CSRNP3	0.143
CCDC85C	CSRNP3	0.143
PPP1CC	GABBR1	0.104
PPP1CA	GABBR1	0.104
PPP1R7	GABBR1	0.076
PPP1CB	GABBR1	0.072
C12orf57	CSRNP3	0.055
PPP1R37	PPP1CC	0.041	0.2
FRMD6	PPP1CC	0.038	0.218
SH2D4A	CSRNP2	0.034
CSRNP1	SH2D4A	0.034
PPP1CB	FRMD6	0.031	0.144
PPP1R37	SH2D4A	0.028	0.09	mutually_exclusive (P62136)
SH2D4A	ZFYVE9	0.028	0.072	mutually_exclusive (P62140)
PPP1R13B	SH2D4A	0.028	0.102
TANC2	GABBR1	0.027
PPP1R7	RASIP1	0.027	0.056
SH2D4A	PLCL2	0.021	0.104	mutually_exclusive (P62136)
CCDC85B	SH2D4A	0.011	0.118
PPP1R7	FRMD6	0.01	0.074
PPP1CA	FRMD6	0.009	0.21

Related Complexes

Genename	Complexes
PPP1R8	huMAP3_02357.1 huMAP3_03508.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1
CSRNP1	huMAP3_00020.1 huMAP3_04660.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_13731.1 huMAP3_14504.1
PPP1R11	huMAP3_02357.1 huMAP3_03459.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1
CCDC85C	huMAP3_00020.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1
PPP1R2	huMAP3_00020.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_14504.1
PPP1R13B	huMAP3_00020.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1 huMAP3_14934.1
PPP1R18	huMAP3_02389.1 huMAP3_06304.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_12990.1 huMAP3_14504.1
RASSF8	huMAP3_00531.1 huMAP3_01036.1 huMAP3_06269.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09641.1 huMAP3_10148.1 huMAP3_10898.1 huMAP3_12886.1 huMAP3_14118.1
LMTK2	huMAP3_02357.1 huMAP3_03508.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1
PPP1R7	huMAP3_00020.1 huMAP3_06341.1 huMAP3_07068.1 huMAP3_07847.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_13731.1 huMAP3_14504.1
KIF18A	huMAP3_02357.1 huMAP3_03508.1 huMAP3_04725.1 huMAP3_06341.1 huMAP3_06422.1 huMAP3_07678.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1
FRMD6	huMAP3_01036.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1
C2orf74	huMAP3_00020.1 huMAP3_04660.1 huMAP3_05534.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_14504.1
CSRNP3	huMAP3_02357.1 huMAP3_06304.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_12186.1 huMAP3_14504.1
TANC2	huMAP3_00020.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_06990.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_14504.1 huMAP3_15308.1
PPP1CC	huMAP3_02357.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_12186.1 huMAP3_14504.1
RASIP1	huMAP3_02389.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_12990.1 huMAP3_14504.1
ZFYVE9	huMAP3_00020.1 huMAP3_00500.1 huMAP3_05180.1 huMAP3_06304.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09080.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_11389.1 huMAP3_13623.1 huMAP3_14504.1 huMAP3_14587.1
PLCL2	huMAP3_00020.1 huMAP3_01131.1 huMAP3_04472.1 huMAP3_04660.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_12977.1 huMAP3_14504.1 huMAP3_15010.1
C12orf57	huMAP3_00020.1 huMAP3_06304.1 huMAP3_07520.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09903.1 huMAP3_10148.1 huMAP3_12756.1 huMAP3_13598.1 huMAP3_14504.1
CSRNP2	huMAP3_02357.1 huMAP3_04660.1 huMAP3_05534.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_12990.1 huMAP3_14504.1
CCDC85B	huMAP3_00020.1 huMAP3_00172.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1
RASSF7	huMAP3_00020.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1 huMAP3_14915.1
PPP1CB	huMAP3_00020.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_14504.1
PPP1R37	huMAP3_00020.1 huMAP3_04660.1 huMAP3_05534.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_12339.1 huMAP3_13724.1 huMAP3_13803.1 huMAP3_14504.1
CNST	huMAP3_02357.1 huMAP3_03459.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1
PPP1R13L	huMAP3_04883.1 huMAP3_06341.1 huMAP3_06990.1 huMAP3_10148.1 huMAP3_10691.1 huMAP3_11737.1 huMAP3_14504.1
ZFYVE16	huMAP3_02357.1 huMAP3_03508.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1
PPP1CA	huMAP3_00020.1 huMAP3_04660.1 huMAP3_05534.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_14504.1
TP53BP2	huMAP3_01036.1 huMAP3_06304.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_14118.1 huMAP3_14504.1
SH2D4A	huMAP3_00020.1 huMAP3_06341.1 huMAP3_07068.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09861.1 huMAP3_10148.1 huMAP3_12421.1 huMAP3_14504.1
SHOC2	huMAP3_00020.1 huMAP3_04660.1 huMAP3_05534.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_11317.1 huMAP3_12693.1 huMAP3_13348.1 huMAP3_14504.1 huMAP3_15206.1
GABBR1	huMAP3_04883.1 huMAP3_10148.1 huMAP3_10691.1 huMAP3_11737.1 huMAP3_12279.1 huMAP3_14296.1 huMAP3_14504.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10148.1

Complex Portal: CPX-22176