hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10155.1
Complex Portal: CPX-23382
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PKD2 | Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2) | 5 | UniProt NCBI |
| CNGA4 | Cyclic nucleotide-gated cation channel alpha-4 (Cyclic nucleotide-gated channel alpha-4) (CNG channel alpha-4) (CNG-4) (CNG4) | 5 | UniProt NCBI |
| PKD2L2 | Polycystin-2-like protein 2 (Polycystin-2L2) (Polycystic kidney disease 2-like 2 protein) (Polycystin-L2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5620916 | 0.00104246243986 | 0.666666666667 | CNGA4 PKD2 | VxPx cargo-targeting to cilium |
| REAC:R-HSA-5620920 | 0.00704293704569 | 0.666666666667 | CNGA4 PKD2 | Cargo trafficking to the periciliary membrane |
| CORUM:1071 | 0.0249718442456 | 0.333333333333 | PKD2 | PKD2-FPC complex |
| CORUM:1927 | 0.0499402709677 | 0.333333333333 | PKD2 | PKD2-PACS1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PKD2 | PKD2L2 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| PKD2 | CNGA4 | 0.957 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes