hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10169.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TSFM | Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt) | 5 | UniProt NCBI |
| CLPP | ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp) | 5 | UniProt NCBI |
| PPA2 | Inorganic pyrophosphatase 2, mitochondrial (EC 3.6.1.1) (Pyrophosphatase SID6-306) (Pyrophosphate phospho-hydrolase 2) (PPase 2) | 5 | UniProt NCBI |
| NHERF1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:682 | 0.0249718442456 | 0.25 | NHERF1 | C-CFTR-NHERF-ezrin complex |
| CORUM:687 | 0.0249718442456 | 0.25 | NHERF1 | CFTR-NHERF-beta(2)AR signaling complex |
| CORUM:3988 | 0.0249718442456 | 0.25 | CLPP | ClpP complex, heptameric |
| CORUM:6791 | 0.0249718442456 | 0.25 | NHERF1 | NHERF1-NPT2A-EZR complex |
| CORUM:3992 | 0.049938562206 | 0.25 | CLPP | ClpXP complex |
| CORUM:6702 | 0.049938562206 | 0.25 | NHERF1 | CXCR2-NHERF1-PLC-beta-3 complex |
| CORUM:6788 | 0.049938562206 | 0.25 | NHERF1 | SLC9A3R1-ACTN4 complex |
| CORUM:6790 | 0.049938562206 | 0.25 | NHERF1 | NHERF1-PRKCZ complex |
| CORUM:6793 | 0.049938562206 | 0.25 | NHERF1 | PDZK1-NHERF1-EZR complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TSFM | PPA2 | 0.978 | 0.158 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM fraction |
| TSFM | NHERF1 | 0.971 | 0.056 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction |
| CLPP | PPA2 | 0.97 | 0.17 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| CLPP | TSFM | 0.904 | 0.556 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| NHERF1 | PPA2 | 0.539 | 0.056 | bioplex_WMM bioplex3_WMM fraction |
| CLPP | NHERF1 | 0.154 | 0.122 | bioplex_WMM bioplex3_WMM gupta_WMM fraction |
Related Complexes