hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10170.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHGA | Chromogranin-A (CgA) (Pituitary secretory protein I) (SP-I) [Cleaved into: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; Catestatin (SL21); AL-11; GV-19; GR-44; ER-37; GE-25; Serpinin-RRG; Serpinin; p-Glu serpinin precursor] | 5 | UniProt NCBI |
| GDNF | Glial cell line-derived neurotrophic factor (hGDNF) (Astrocyte-derived trophic factor) (ATF) | 5 | UniProt NCBI |
| VIP | VIP peptides [Cleaved into: Intestinal peptide PHV-42 (Peptide histidine valine 42); Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)] | 5 | UniProt NCBI |
| XPNPEP3 | Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3) | 5 | UniProt NCBI |
| FGF19 | Fibroblast growth factor 19 (FGF-19) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6832 | 0.0249718442456 | 0.25 | FGF19 | FGF19-FGFR4-KLB complex, heparin induced |
| KEGG:04020 | 0.036316189849 | 0.5 | GDNF FGF19 | Calcium signaling pathway |
| CORUM:6684 | 0.049938562206 | 0.25 | XPNPEP3 | TNFR2 signaling complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| VIP | XPNPEP3 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| XPNPEP3 | GDNF | 0.97 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| XPNPEP3 | CHGA | 0.965 | 0.016 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| XPNPEP3 | FGF19 | 0.956 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes