hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10195.1

Complex Portal: CPX-17759

Confidence: Medium High

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Genename	Protein Name	Uniprot Annotation Score	Links
ADGRL2	Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin homolog 1) (Latrophilin-2) (Lectomedin-1)	5	UniProt NCBI
ATP12A	Potassium-transporting ATPase alpha chain 2 (HK alpha 2) (Non-gastric H(+)/K(+) ATPase subunit alpha) (EC 7.2.2.19) (Non-gastric Na(+)/K(+) ATPase subunit alpha) (EC 7.2.2.13) (Proton pump) (Sodium pump)	5	UniProt NCBI
ATP1B1	Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1)	5	UniProt NCBI
ATP1B3	Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) (ATPB-3) (CD antigen CD298)	5	UniProt NCBI
FADS2	Acyl-CoA 6-desaturase (EC 1.14.19.3) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase) (Fatty acid desaturase 2)	5	UniProt NCBI
MAIP1	m-AAA protease-interacting protein 1, mitochondrial (Matrix AAA peptidase-interacting protein 1)	5	UniProt NCBI
NDRG3	Protein NDRG3 (N-myc downstream-regulated gene 3 protein)	3	UniProt NCBI

Showing 1 to 7 of 7 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-936837	0.000109213310364	0.428571428571	ATP1B1 ATP12A ATP1B3	Ion transport by P-type ATPases
GO:0030007	0.00040312426486	0.428571428571	ATP1B1 ATP12A ATP1B3	intracellular potassium ion homeostasis
GO:0036376	0.000738757615619	0.428571428571	ATP1B1 ATP12A ATP1B3	sodium ion export across plasma membrane
GO:0090533	0.00152694380207	0.428571428571	ATP1B1 ATP12A ATP1B3	cation-transporting ATPase complex
GO:0006883	0.00152694380207	0.428571428571	ATP1B1 ATP12A ATP1B3	intracellular sodium ion homeostasis
KEGG:04964	0.0019420290898	0.285714285714	ATP1B1 ATP1B3	Proximal tubule bicarbonate reclamation
GO:0055075	0.00273674384085	0.428571428571	ATP1B1 ATP12A ATP1B3	potassium ion homeostasis
GO:0098533	0.00382182132582	0.428571428571	ATP1B1 ATP12A ATP1B3	ATPase dependent transmembrane transport complex
REAC:R-HSA-983712	0.00394439973206	0.428571428571	ATP1B1 ATP12A ATP1B3	Ion channel transport
KEGG:04960	0.0044360875468	0.285714285714	ATP1B1 ATP1B3	Aldosterone-regulated sodium reabsorption

Showing 1 to 10 of 28 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ATP12A	ATP1B1	0.996			bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
ATP1B3	ATP12A	0.994			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM
ADGRL2	ATP1B3	0.989	0.118		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM
ATP1B3	ATP1B1	0.986	0.168		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
FADS2	ATP1B3	0.984	0.104		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM
NDRG3	ATP1B1	0.979	0.016		bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
MAIP1	ATP1B1	0.966	0.012		bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only
NDRG3	ATP1B3	0.964	0.016		bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only
FADS2	ATP1B1	0.71	0.116		bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only
ATP1B3	MAIP1	0.606	0.064		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM

Showing 1 to 10 of 21 entries

Related Complexes

Genename	Complexes
FADS2	huMAP3_01819.1 huMAP3_02584.1 huMAP3_05445.1 huMAP3_06361.1 huMAP3_06842.1 huMAP3_07941.1 huMAP3_08115.1 huMAP3_10195.1
ATP12A	huMAP3_04972.1 huMAP3_06361.1 huMAP3_07575.1 huMAP3_10195.1 huMAP3_11165.1
ATP1B1	huMAP3_04972.1 huMAP3_07108.1 huMAP3_07410.1 huMAP3_08156.1 huMAP3_09007.1 huMAP3_09189.1 huMAP3_09747.1 huMAP3_10195.1 huMAP3_12258.1
NDRG3	huMAP3_00533.1 huMAP3_04972.1 huMAP3_06361.1 huMAP3_06522.1 huMAP3_07108.1 huMAP3_07960.1 huMAP3_09007.1 huMAP3_09189.1 huMAP3_09747.1 huMAP3_10195.1 huMAP3_12258.1 huMAP3_13561.1 huMAP3_13756.1
ATP1B3	huMAP3_02584.1 huMAP3_06361.1 huMAP3_06522.1 huMAP3_06791.1 huMAP3_10195.1 huMAP3_13561.1
MAIP1	huMAP3_03315.1 huMAP3_04972.1 huMAP3_05462.1 huMAP3_07108.1 huMAP3_08156.1 huMAP3_08619.1 huMAP3_09889.1 huMAP3_10008.1 huMAP3_10195.1
ADGRL2	huMAP3_01059.1 huMAP3_02584.1 huMAP3_06275.1 huMAP3_06361.1 huMAP3_07853.1 huMAP3_10195.1 huMAP3_12150.1 huMAP3_14838.1