hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10200.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| C1orf198 | Uncharacterized protein C1orf198 | 3 | UniProt NCBI |
| SOWAHB | Ankyrin repeat domain-containing protein SOWAHB (Ankyrin repeat domain-containing protein 56) (Protein sosondowah homolog B) | 3 | UniProt NCBI |
| DAAM1 | Disheveled-associated activator of morphogenesis 1 | 5 | UniProt NCBI |
| DIAPH2 | Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) | 5 | UniProt NCBI |
| RHOD | Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1) | 5 | UniProt NCBI |
| DIAPH1 | Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9012999 | 0.00137431571924 | 0.666666666667 | DAAM1 DIAPH1 RHOD DIAPH2 | RHO GTPase cycle |
| REAC:R-HSA-5663220 | 0.00259573483155 | 0.5 | DAAM1 RHOD DIAPH1 | RHO GTPases Activate Formins |
| REAC:R-HSA-194315 | 0.0087987737143 | 0.666666666667 | DAAM1 DIAPH1 RHOD DIAPH2 | Signaling by Rho GTPases |
| REAC:R-HSA-9716542 | 0.00959411672385 | 0.666666666667 | DAAM1 DIAPH1 RHOD DIAPH2 | Signaling by Rho GTPases, Miro GTPases and RHOBTB3 |
| REAC:R-HSA-9035034 | 0.0220691409046 | 0.333333333333 | DIAPH2 DIAPH1 | RHOF GTPase cycle |
| REAC:R-HSA-195258 | 0.0288975569845 | 0.5 | DAAM1 RHOD DIAPH1 | RHO GTPase Effectors |
| REAC:R-HSA-9013405 | 0.0326270815028 | 0.333333333333 | DIAPH1 RHOD | RHOD GTPase cycle |
| REAC:R-HSA-9013026 | 0.0467439411123 | 0.333333333333 | DAAM1 DIAPH1 | RHOB GTPase cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| C1orf198 | RHOD | 0.999 | 0.246 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RHOD | DAAM1 | 0.996 | 0.384 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RHOD | DIAPH2 | 0.996 | 0.210333333333 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| C1orf198 | DAAM1 | 0.995 | 0.184 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| SOWAHB | DIAPH2 | 0.991 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| RHOD | DIAPH1 | 0.99 | 0.416 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SOWAHB | DIAPH1 | 0.972 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DIAPH1 | DAAM1 | 0.848 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only |
| C1orf198 | DIAPH1 | 0.815 | 0.114 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| C1orf198 | DIAPH2 | 0.715 | 0.086 | bioplex3_WMM WMM_only |
| DIAPH1 | DIAPH2 | 0.407 | 0.164 | bioplex3_WMM youn_WMM WMM_only |
| DAAM1 | DIAPH2 | 0.267 | 0.078 | bioplex3_WMM WMM_only |
Related Complexes