hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10201.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NMT2 | Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Peptide N-myristoyltransferase 2) (Protein-lysine myristoyltransferase NMT2) (EC 2.3.1.-) (Type II N-myristoyltransferase) | 5 | UniProt NCBI |
| PRPSAP2 | Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41) | 5 | UniProt NCBI |
| TRIM7 | E3 ubiquitin-protein ligase TRIM7 (EC 2.3.2.27) (Glycogenin-interacting protein) (RING finger protein 90) (Tripartite motif-containing protein 7) | 5 | UniProt NCBI |
| PRPSAP1 | Phosphoribosyl pyrophosphate synthase-associated protein 1 (PRPP synthase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthase-associated protein) (PAP39) | 5 | UniProt NCBI |
| PRPS1 | Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase I) (PRS-I) | 5 | UniProt NCBI |
| IVNS1ABP | Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3) (Kelch-like protein 39) | 5 | UniProt NCBI |
| PRPS2 | Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase II) (PRS-II) | 5 | UniProt NCBI |
| ELP1 | Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein) (p150) | 5 | UniProt NCBI |
| LIPE | Hormone-sensitive lipase (HSL) (EC 3.1.1.79) (Monoacylglycerol lipase LIPE) (EC 3.1.1.23) (Retinyl ester hydrolase) (REH) | 5 | UniProt NCBI |
| PRPS1L1 | Ribose-phosphate pyrophosphokinase 3 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 1-like 1) (PRPS1-like 1) (Phosphoribosyl pyrophosphate synthase III) (PRS-III) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0004749 | 5.37995977657e-05 | 0.375 | PRPSAP2 PRPS1 PRPSAP1 | ribose phosphate diphosphokinase activity |
| GO:0002189 | 5.37995977657e-05 | 0.375 | PRPSAP2 PRPS1 PRPSAP1 | ribose phosphate diphosphokinase complex |
| GO:0006015 | 5.37995977657e-05 | 0.375 | PRPSAP2 PRPS1 PRPSAP1 | 5-phosphoribose 1-diphosphate biosynthetic process |
| GO:0046391 | 5.37995977657e-05 | 0.375 | PRPSAP2 PRPS1 PRPSAP1 | 5-phosphoribose 1-diphosphate metabolic process |
| GO:0016778 | 0.00010757157937 | 0.375 | PRPSAP2 PRPS1 PRPSAP1 | diphosphotransferase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PRPS2 | PRPSAP2 | 1.0 | 0.262 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 fraction boldt_WMM |
| PRPSAP2 | PRPS1 | 1.0 | 0.192 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction |
| PRPS1 | PRPSAP1 | 1.0 | 0.13 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM hein () bioplex3_HCT116 fraction |
| PRPSAP2 | PRPS1L1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PRPS2 | PRPSAP1 | 1.0 | 0.302 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM bioplex3_HCT116 fraction treiber_WMM |
| PRPSAP2 | PRPSAP1 | 1.0 | 0.264 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| PRPS2 | PRPS1 | 0.999 | 0.454 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
| PRPS1 | PRPS1L1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| IVNS1ABP | PRPSAP1 | 0.999 | 0.132 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PRPSAP2 | IVNS1ABP | 0.995 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PRPS2 | PRPS1L1 | 0.992 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PRPS1 | IVNS1ABP | 0.987 | 0.076 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| PRPSAP1 | TRIM7 | 0.986 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PRPS2 | NMT2 | 0.985 | 0.088 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| PRPS1 | LIPE | 0.973 | 0.31 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| PRPS2 | TRIM7 | 0.967 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NMT2 | PRPS1 | 0.967 | 0.102 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| ELP1 | PRPS2 | 0.958 | 0.14 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| ELP1 | PRPS1 | 0.954 | 0.186 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| PRPS1L1 | PRPSAP1 | 0.95 | bioplex_WMM bioplex3_WMM WMM_only | |
| PRPS2 | IVNS1ABP | 0.918 | 0.128 | bioplex_WMM bioplex3_WMM WMM_only |
| NMT2 | PRPSAP1 | 0.912 | 0.094 | bioplex_WMM bioplex3_WMM WMM_only |
| NMT2 | PRPS1L1 | 0.88 | bioplex_WMM bioplex3_WMM WMM_only | |
| NMT2 | PRPSAP2 | 0.843 | 0.098 | bioplex_WMM bioplex3_WMM WMM_only |
| PRPSAP2 | LIPE | 0.703 | 0.144 | bioplex3_WMM WMM_only |
| LIPE | PRPS1L1 | 0.674 | bioplex3_WMM WMM_only | |
| PRPSAP2 | TRIM7 | 0.634 | bioplex3_WMM WMM_only | |
| PRPS1 | TRIM7 | 0.5 | bioplex3_WMM WMM_only | |
| LIPE | PRPSAP1 | 0.437 | 0.046 | bioplex3_WMM WMM_only |
| PRPS2 | LIPE | 0.388 | 0.188 | bioplex3_WMM WMM_only |
| IVNS1ABP | PRPS1L1 | 0.297 | bioplex_WMM bioplex3_WMM WMM_only | |
| IVNS1ABP | LIPE | 0.255 | 0.032 | bioplex3_WMM WMM_only |
| ELP1 | NMT2 | 0.216 | 0.108 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| PRPS1L1 | TRIM7 | 0.198 | bioplex3_WMM WMM_only | |
| NMT2 | LIPE | 0.188 | 0.04 | bioplex3_WMM WMM_only |
| NMT2 | TRIM7 | 0.102 | bioplex3_WMM WMM_only | |
| ELP1 | PRPS1L1 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| IVNS1ABP | TRIM7 | 0.074 | bioplex3_WMM WMM_only | |
| ELP1 | TRIM7 | 0.071 | bioplex3_WMM WMM_only | |
| NMT2 | IVNS1ABP | 0.066 | 0.018 | bioplex3_WMM WMM_only |
| ELP1 | PRPSAP1 | 0.055 | 0.092 | bioplex_WMM bioplex3_WMM WMM_only |
| ELP1 | PRPSAP2 | 0.055 | 0.114 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM |
| ELP1 | LIPE | 0.04 | 0.102 | bioplex3_WMM WMM_only |
| ELP1 | IVNS1ABP | 0.025 | 0.225428571429 | bioplex3_WMM WMM_only |
Related Complexes