hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10208.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GGT5 | Glutathione hydrolase 5 proenzyme (EC 3.4.19.13) (Gamma-glutamyl transpeptidase-related enzyme) (GGT-rel) (Gamma-glutamyltransferase 5) (GGT 5) (EC 2.3.2.2) (Gamma-glutamyltransferase-like activity 1) (Gamma-glutamyltranspeptidase 5) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) [Cleaved into: Glutathione hydrolase 5 heavy chain; Glutathione hydrolase 5 light chain] | 5 | UniProt NCBI |
| MVK | Mevalonate kinase (MK) (EC 2.7.1.36) | 5 | UniProt NCBI |
| SPACA4 | Sperm acrosome membrane-associated protein 4 (Sperm acrosomal membrane-associated protein 14) | 4 | UniProt NCBI |
| ANGPTL3 | Angiopoietin-related protein 3 (Angiopoietin-5) (ANG-5) (Angiopoietin-like protein 3) [Cleaved into: ANGPTL3(17-221); ANGPTL3(17-224)] | 5 | UniProt NCBI |
| CCDC91 | Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein) | 5 | UniProt NCBI |
| LEF1 | Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5304 | 0.0182415379951 | 0.333333333333 | MVK ANGPTL3 | Cholesterol metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MVK | CCDC91 | 0.997 | 0.052 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| GGT5 | MVK | 0.986 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| MVK | SPACA4 | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MVK | LEF1 | 0.983 | 0.04 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| CCDC91 | ANGPTL3 | 0.962 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes