hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10238.1
Complex Portal: CPX-15734
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADCYAP1 | Pituitary adenylate cyclase-activating polypeptide (PACAP) [Cleaved into: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)] | 5 | UniProt NCBI |
| KLHL33 | Kelch-like protein 33 | 2 | UniProt NCBI |
| SAV1 | Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45) | 5 | UniProt NCBI |
| AMER1 | APC membrane recruitment protein 1 (Amer1) (Protein FAM123B) (Wilms tumor gene on the X chromosome protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6403 | 0.049938562206 | 0.25 | SAV1 | MST1-SAV1 complex |
| CORUM:6404 | 0.049938562206 | 0.25 | SAV1 | MST2-SAV1 complex |
| REAC:R-HSA-187015 | 0.0499436884912 | 0.25 | ADCYAP1 | Activation of TRKA receptors |
| REAC:R-HSA-187024 | 0.0499436884912 | 0.25 | ADCYAP1 | NGF-independant TRKA activation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| AMER1 | SAV1 | 0.99 | 0.098 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| ADCYAP1 | SAV1 | 0.98 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| KLHL33 | SAV1 | 0.966 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes