hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10240.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NUBP2 | Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2) | 5 | UniProt NCBI |
| PELO | Protein pelota homolog (hPelota) (Protein Dom34 homolog) | 5 | UniProt NCBI |
| IRAK1 | Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1) | 5 | UniProt NCBI |
| GART | Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] | 5 | UniProt NCBI |
| FBXL12 | F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12) | 4 | UniProt NCBI |
| COQ8A | Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3) | 5 | UniProt NCBI |
| PGM3 | Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3) | 5 | UniProt NCBI |
| UMPS | Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (ODC) (OMPD) (EC 4.1.1.23) (OMPdecase)] | 5 | UniProt NCBI |
| MSH6 | DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160) | 5 | UniProt NCBI |
| GGT7 | Glutathione hydrolase 7 (EC 3.4.19.13) (Gamma-glutamyltransferase 7) (GGT 7) (EC 2.3.2.2) (Gamma-glutamyltransferase-like 3) (Gamma-glutamyltransferase-like 5) (Gamma-glutamyltranspeptidase 7) [Cleaved into: Glutathione hydrolase 7 heavy chain; Glutathione hydrolase 7 light chain] | 5 | UniProt NCBI |
| GALK1 | Galactokinase (EC 2.7.1.6) (Galactose kinase) | 5 | UniProt NCBI |
| ARL1 | ADP-ribosylation factor-like protein 1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:01250 | 0.0124732668167 | 0.2 | PGM3 GALK1 | Biosynthesis of nucleotide sugars |
| HPA:0091022 | 0.0137099229357 | 0.3 | PGM3 IRAK1 MSH6 | cerebellum; processes in granular layer[>=Medium] |
| KEGG:00520 | 0.0206782019073 | 0.2 | PGM3 GALK1 | Amino sugar and nucleotide sugar metabolism |
| HPA:0091021 | 0.0215195527 | 0.3 | PGM3 IRAK1 MSH6 | cerebellum; processes in granular layer[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| FBXL12 | NUBP2 | 0.991 | 0.082 |
| PELO | GGT7 | 0.989 | 0.052 |
| IRAK1 | ARL1 | 0.989 | 0.092 |
| FBXL12 | GALK1 | 0.988 | 0.072 |
| NUBP2 | IRAK1 | 0.988 | 0.128 |
| FBXL12 | PELO | 0.985 | 0.03 |
| PELO | UMPS | 0.982 | 0.122 |
| FBXL12 | UMPS | 0.981 | 0.13 |
| IRAK1 | UMPS | 0.981 | 0.202 |
| GART | IRAK1 | 0.979 | 0.136 |
| UMPS | ARL1 | 0.973 | 0.21 |
| PELO | MSH6 | 0.972 | 0.044 |
| FBXL12 | ARL1 | 0.972 | 0.094 |
| GART | NUBP2 | 0.97 | 0.11 |
| FBXL12 | COQ8A | 0.968 | 0.074 |
| NUBP2 | GALK1 | 0.965 | 0.062 |
| PGM3 | COQ8A | 0.963 | 0.11 |
| NUBP2 | GGT7 | 0.962 | 0.07 |
| NUBP2 | UMPS | 0.962 | 0.148 |
| IRAK1 | GGT7 | 0.96 | 0.062 |
| PGM3 | GALK1 | 0.96 | 0.038 |
| MSH6 | GALK1 | 0.959 | 0.046 |
| PELO | COQ8A | 0.954 | 0.02 |
| FBXL12 | GGT7 | 0.954 | 0.09 |
| FBXL12 | MSH6 | 0.952 | 0.058 |
| PELO | GALK1 | 0.952 | 0.016 |
| PELO | NUBP2 | 0.951 | 0.106 |
| PELO | IRAK1 | 0.941 | 0.13 |
| UMPS | GALK1 | 0.94 | 0.108 |
| MSH6 | IRAK1 | 0.9 | 0.064 |
| MSH6 | COQ8A | 0.892 | 0.088 |
| FBXL12 | IRAK1 | 0.889 | 0.064 |
| PELO | GART | 0.868 | 0.13 |
| IRAK1 | GALK1 | 0.851 | 0.046 |
| FBXL12 | PGM3 | 0.818 | 0.054 |
| UMPS | GGT7 | 0.815 | 0.038 |
| UMPS | COQ8A | 0.814 | 0.103333333333 |
| GART | UMPS | 0.812 | 0.306 |
| PELO | ARL1 | 0.806 | 0.076 |
| IRAK1 | COQ8A | 0.804 | 0.042 |
| NUBP2 | ARL1 | 0.796 | 0.048 |
| ARL1 | COQ8A | 0.758 | 0.092 |
| MSH6 | UMPS | 0.752 | 0.13 |
| MSH6 | PGM3 | 0.751 | 0.088 |
| FBXL12 | GART | 0.724 | 0.118 |
| UMPS | PGM3 | 0.714 | 0.146 |
| GGT7 | ARL1 | 0.674 | 0.068 |
| MSH6 | ARL1 | 0.666 | 0.044 |
| NUBP2 | PGM3 | 0.591 | 0.07 |
| MSH6 | NUBP2 | 0.531 | 0.06 |
| PELO | PGM3 | 0.478 | 0.056 |
| PGM3 | ARL1 | 0.417 | 0.04 |
| IRAK1 | PGM3 | 0.364 | 0.094 |
| GGT7 | GALK1 | 0.359 | 0.062 |
| GALK1 | COQ8A | 0.242 | 0.046 |
| NUBP2 | COQ8A | 0.183 | 0.05 |
| GART | GALK1 | 0.127 | 0.196 |
| GART | PGM3 | 0.074 | 0.226 |
| GALK1 | ARL1 | 0.06 | 0.052 |
| GGT7 | PGM3 | 0.058 | 0.054 |
| GART | MSH6 | 0.056 | 0.244 |
| GART | ARL1 | 0.05 | 0.104 |
| GART | COQ8A | 0.05 | 0.156 |
| MSH6 | GGT7 | 0.043 | 0.032 |
| GART | GGT7 | 0.041 | 0.0865588235294 |
| GGT7 | COQ8A | 0.033 | 0.056 |
Related Complexes