hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10245.1
Complex Portal: CPX-23506
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC6A5 | Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) | 5 | UniProt NCBI |
| ATP5PO | ATP synthase subunit O, mitochondrial (ATP synthase peripheral stalk subunit OSCP) (Oligomycin sensitivity conferral protein) (OSCP) | 5 | UniProt NCBI |
| ACKR3 | Atypical chemokine receptor 3 (C-X-C chemokine receptor type 7) (CXC-R7) (CXCR-7) (Chemokine orphan receptor 1) (G-protein coupled receptor 159) (G-protein coupled receptor RDC1 homolog) (RDC-1) | 5 | UniProt NCBI |
| SLC38A5 | Sodium-coupled neutral amino acid transporter 5 (Solute carrier family 38 member 5) (System N transporter 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0015187 | 0.0294899169624 | 0.666666666667 | SLC38A5 SLC6A5 | glycine transmembrane transporter activity |
| GO:0015816 | 0.0294899169624 | 0.666666666667 | SLC38A5 SLC6A5 | glycine transport |
| REAC:R-HSA-5619089 | 0.0498224659464 | 0.333333333333 | SLC6A5 | Defective SLC6A5 causes hyperekplexia 3 (HKPX3) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ATP5PO | SLC6A5 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ATP5PO | ACKR3 | 0.977 | 0.096 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () | |
| ATP5PO | SLC38A5 | 0.954 | 0.088 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| SLC38A5 | SLC6A5 | 0.02 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes