hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10249.1

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
KDM5C	Lysine-specific demethylase 5C (EC 1.14.11.67) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) ([histone H3]-trimethyl-L-lysine(4) demethylase 5C)	5	UniProt NCBI
GTF3C5	General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon)	5	UniProt NCBI
GTF3C3	General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma)	5	UniProt NCBI
GTF3C1	General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha)	5	UniProt NCBI
ZNF688	Zinc finger protein 688	5	UniProt NCBI
USP34	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)	5	UniProt NCBI
GTF3C4	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (TF3C-delta) (Transcription factor IIIC 90 kDa subunit) (TFIIIC 90 kDa subunit) (TFIIIC90) (Transcription factor IIIC subunit delta)	5	UniProt NCBI
NEBL	Nebulette (Actin-binding Z-disk protein)	5	UniProt NCBI
PNMA2	Paraneoplastic antigen Ma2 (40 kDa neuronal protein) (Onconeuronal antigen Ma2) (Paraneoplastic neuronal antigen MM2)	5	UniProt NCBI
ZNF764	Zinc finger protein 764	5	UniProt NCBI
LASP1	LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:1105	5.76350611564e-11	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	transcription factor IIIC multisubunit complex
CORUM:1101	5.76350611564e-11	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	transcription factor IIIC multisubunit complex
CORUM:1113	5.76350611564e-11	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	5S-DNA-TFIIIA-TFIIIC2 subcomplex
CORUM:1106	1.72838910881e-10	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	TFIIIC containing-TOP1-SUB1 complex
CORUM:1114	4.03136208942e-10	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex
GO:0000127	1.30147699894e-07	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	transcription factor TFIIIC complex
GO:0042791	1.30147699894e-07	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	5S class rRNA transcription by RNA polymerase III
GO:0090576	6.06890408176e-07	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	RNA polymerase III transcription regulator complex
REAC:R-HSA-76066	6.66957015538e-07	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	RNA Polymerase III Transcription Initiation From Type 2 Promoter
REAC:R-HSA-76061	6.66957015538e-07	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	RNA Polymerase III Transcription Initiation From Type 1 Promoter
GO:0042797	1.81927560642e-06	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	tRNA transcription by RNA polymerase III
REAC:R-HSA-76046	2.06260783556e-06	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	RNA Polymerase III Transcription Initiation
GO:0009304	2.85776567317e-06	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	tRNA transcription
REAC:R-HSA-749476	3.65116149301e-06	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	RNA Polymerase III Abortive And Retractive Initiation
REAC:R-HSA-74158	3.65116149301e-06	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	RNA Polymerase III Transcription
GO:0000995	4.28500508143e-06	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	RNA polymerase III general transcription initiation factor activity
GO:0009303	0.000204265929084	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	rRNA transcription
GO:0006383	0.00166128673178	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	transcription by RNA polymerase III
GO:0140223	0.00166128673178	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	general transcription initiation factor activity
REAC:R-HSA-74160	0.0390724328074	0.545454545455	GTF3C3 GTF3C1 ZNF764 ZNF688 GTF3C4 GTF3C5	Gene expression (Transcription)
GO:0098781	0.0399279910051	0.363636363636	GTF3C4 GTF3C1 GTF3C5 GTF3C3	ncRNA transcription

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
GTF3C5	GTF3C3	1.0	0.97	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () Malo gupta_WMM fraction boldt_WMM
GTF3C1	GTF3C3	1.0	0.866	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () Malo gupta_WMM fraction boldt_WMM
GTF3C5	GTF3C1	1.0	0.684	hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM
GTF3C4	GTF3C5	1.0	0.558	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM
ZNF764	NEBL	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GTF3C4	GTF3C1	0.999	0.538	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM
GTF3C4	GTF3C3	0.999	0.63	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 boldt_WMM
GTF3C1	ZNF764	0.998		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GTF3C3	ZNF764	0.998		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ZNF764	KDM5C	0.995		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
GTF3C3	KDM5C	0.994		bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
PNMA2	GTF3C3	0.994	0.09	bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
GTF3C1	PNMA2	0.993	0.088	bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
KDM5C	NEBL	0.992		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
GTF3C1	KDM5C	0.99		bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
GTF3C4	ZNF764	0.989		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GTF3C4	ZNF688	0.984		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
GTF3C5	KDM5C	0.984		bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
USP34	ZNF764	0.98		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GTF3C5	PNMA2	0.964	0.13	bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
GTF3C5	ZNF764	0.952		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
LASP1	ZNF764	0.951		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GTF3C4	KDM5C	0.775		bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
GTF3C3	USP34	0.488	0.104	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
ZNF688	GTF3C1	0.467		bioplex3_WMM WMM_only
ZNF688	ZNF764	0.415		bioplex3_WMM WMM_only
GTF3C3	NEBL	0.407	0.032	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
GTF3C5	USP34	0.39	0.078	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
GTF3C5	NEBL	0.389	0.058	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
GTF3C4	NEBL	0.375	0.052	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM
GTF3C4	PNMA2	0.253	0.082	bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
ZNF688	GTF3C3	0.249		bioplex3_WMM WMM_only
LASP1	NEBL	0.205	0.096	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
ZNF688	GTF3C5	0.201		bioplex3_WMM WMM_only
USP34	NEBL	0.164	0.092	bioplex_WMM bioplex3_WMM WMM_only
USP34	KDM5C	0.082		bioplex3_WMM WMM_only
GTF3C1	NEBL	0.081	0.12	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
USP34	LASP1	0.055	0.032	bioplex_WMM bioplex3_WMM WMM_only
GTF3C1	USP34	0.048	0.172	bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM
PNMA2	USP34	0.025	0.068	bioplex_WMM bioplex3_WMM WMM_only
GTF3C4	USP34	0.017	0.094	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
ZNF688	LASP1	0.016		bioplex3_WMM WMM_only
GTF3C5	LASP1	0.012	0.006	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
GTF3C1	LASP1	0.007	0.042	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
GTF3C3	LASP1	0.007	0.024	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
GTF3C4	LASP1	0.006	0.058	bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only

Related Complexes

Genename	Complexes
KDM5C	huMAP3_02445.1 huMAP3_05598.1 huMAP3_05651.1 huMAP3_07997.1 huMAP3_08803.1 huMAP3_09735.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_12568.1 huMAP3_14801.1
GTF3C5	huMAP3_00436.1 huMAP3_01637.1 huMAP3_08803.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_14801.1
GTF3C3	huMAP3_00436.1 huMAP3_01637.1 huMAP3_08803.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_14801.1
GTF3C1	huMAP3_00436.1 huMAP3_01637.1 huMAP3_08803.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_14801.1
ZNF688	huMAP3_00337.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_12845.1 huMAP3_13267.1 huMAP3_13532.1 huMAP3_13752.1 huMAP3_14801.1
USP34	huMAP3_00495.1 huMAP3_03862.1 huMAP3_04224.1 huMAP3_07101.1 huMAP3_07997.1 huMAP3_08114.1 huMAP3_08803.1 huMAP3_09735.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10851.1
GTF3C4	huMAP3_00337.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_13752.1 huMAP3_14801.1
NEBL	huMAP3_05212.1 huMAP3_05598.1 huMAP3_09735.1 huMAP3_10249.1 huMAP3_12222.1 huMAP3_12568.1 huMAP3_14799.1
PNMA2	huMAP3_00436.1 huMAP3_01637.1 huMAP3_02082.1 huMAP3_04000.1 huMAP3_07519.1 huMAP3_07912.1 huMAP3_08726.1 huMAP3_09865.1 huMAP3_09960.1 huMAP3_10249.1 huMAP3_10403.1 huMAP3_10875.1 huMAP3_11689.1
ZNF764	huMAP3_00495.1 huMAP3_02445.1 huMAP3_05598.1 huMAP3_07997.1 huMAP3_08803.1 huMAP3_09735.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_11486.1 huMAP3_13566.1 huMAP3_14801.1
LASP1	huMAP3_00495.1 huMAP3_03126.1 huMAP3_07837.1 huMAP3_07997.1 huMAP3_08803.1 huMAP3_09735.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_13998.1 huMAP3_14442.1 huMAP3_15220.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10249.1