hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10258.1

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
ZMYM4	Zinc finger MYM-type protein 4 (Zinc finger protein 262)	5	UniProt NCBI
RCOR3	REST corepressor 3	5	UniProt NCBI
GSE1	Genetic suppressor element 1	5	UniProt NCBI
OVOL2	Transcription factor Ovo-like 2 (hOvo2) (Zinc finger protein 339)	5	UniProt NCBI
ZMYM3	Zinc finger MYM-type protein 3 (Zinc finger protein 261)	5	UniProt NCBI
PWWP2A	PWWP domain-containing protein 2A	5	UniProt NCBI
RERE	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein)	5	UniProt NCBI
HMG20B	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (HMG domain-containing protein 2) (HMG domain-containing protein HMGX2) (Sox-like transcriptional factor) (Structural DNA-binding protein BRAF35)	5	UniProt NCBI
PHF12	PHD finger protein 12 (PHD factor 1) (Pf1)	5	UniProt NCBI
PHF21A	PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)	5	UniProt NCBI
EEF1AKMT4-ECE2	EEF1AKMT4-ECE2 readthrough transcript protein (EC 3.4.24.71) [Includes: Methyltransferase-like region (EC 2.1.1.-); Endothelin-converting enzyme 2 region (EC 3.4.24.71)]	5	UniProt NCBI
RCOR1	REST corepressor 1 (Protein CoREST)	5	UniProt NCBI
KDM1A	Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)	5	UniProt NCBI
TRERF1	Transcriptional-regulating factor 1 (Breast cancer anti-estrogen resistance 2) (Transcriptional-regulating protein 132) (Zinc finger protein rapa) (Zinc finger transcription factor TReP-132)	5	UniProt NCBI
ADNP	Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein)	5	UniProt NCBI
DNTTIP1	Deoxynucleotidyltransferase terminal-interacting protein 1 (Terminal deoxynucleotidyltransferase-interacting factor 1) (TdIF1) (TdT-interacting factor 1)	5	UniProt NCBI
ZSCAN5A	Zinc finger and SCAN domain-containing protein 5A (Zinc finger protein 495)	4	UniProt NCBI
ZMYM2	Zinc finger MYM-type protein 2 (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein) (Zinc finger protein 198)	5	UniProt NCBI
RCOR2	REST corepressor 2	3	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:633	2.24260864342e-17	0.368421052632	PHF21A HMG20B ZMYM3 KDM1A ZMYM2 GSE1 RCOR1	anti-BHC110 complex
CORUM:632	1.3159525735e-15	0.368421052632	PHF21A HMG20B ZMYM3 KDM1A ZMYM2 GSE1 RCOR1	Anti-HDAC2 complex
CORUM:1492	1.6034653305e-14	0.315789473684	PHF21A ZMYM2 KDM1A HMG20B GSE1 RCOR1	BHC110 complex
CORUM:626	1.30726370872e-13	0.315789473684	PHF21A ZMYM2 RCOR3 KDM1A HMG20B RCOR1	LSD1 complex
CORUM:636	1.16588129528e-09	0.210526315789	HMG20B KDM1A RCOR1 PHF21A	BHC complex
CORUM:871	2.71815533384e-09	0.210526315789	HMG20B KDM1A RCOR1 PHF21A	BRAF53-BRCA2 complex
CORUM:620	2.71815533384e-09	0.210526315789	HMG20B KDM1A RCOR1 PHF21A	CoREST-HDAC complex
GO:0000118	5.32326883509e-08	0.368421052632	PHF21A RCOR2 TRERF1 DNTTIP1 RCOR3 PHF12 RCOR1	histone deacetylase complex
TF:M10112_1	1.73972532135e-05	0.894736842105	PHF21A ADNP EEF1AKMT4-ECE2 RCOR3 OVOL2 RCOR2 ZMYM3 DNTTIP1 TRERF1 ZMYM2 ZMYM4 PHF12 PWWP2A HMG20B GSE1 RCOR1 KDM1A	Factor: Miz-1; motif: NNRGGWGGGGGAGGGGMRR; match class: 1
CORUM:642	4.77947327477e-05	0.157894736842	RCOR3 RCOR1 KDM1A	CtBP complex
TF:M01118_1	5.27967518385e-05	0.789473684211	PHF21A ADNP RCOR2 RCOR3 OVOL2 ZMYM3 TRERF1 ZMYM2 ZMYM4 PHF12 PWWP2A HMG20B GSE1 RCOR1 KDM1A	Factor: WT1; motif: SMCNCCNSC; match class: 1
CORUM:624	6.11162772017e-05	0.105263157895	RCOR1 KDM1A	LSD1-CoREST complex
CORUM:648	0.000183206632644	0.105263157895	RCOR1 KDM1A	HDAC1-associated core complex cI
TF:M12464_1	0.000265109144545	0.736842105263	PHF21A ADNP EEF1AKMT4-ECE2 RCOR3 HMG20B ZMYM3 TRERF1 ZMYM2 ZMYM4 PWWP2A PHF12 GSE1 RCOR1 RCOR2	Factor: ZNF148; motif: NNCCCCTCCCCC; match class: 1
TF:M01175_1	0.000472828808891	0.736842105263	PHF21A ADNP EEF1AKMT4-ECE2 RCOR3 HMG20B ZMYM3 TRERF1 ZMYM2 ZMYM4 KDM1A PHF12 GSE1 RCOR1 RCOR2	Factor: CKROX; motif: SCCCTCCCC; match class: 1
CORUM:634	0.000609741949881	0.105263157895	ZMYM3 KDM1A	XFIM complex
REAC:R-HSA-3214815	0.00090736193322	0.210526315789	HMG20B KDM1A RCOR1 PHF21A	HDACs deacetylate histones
REAC:R-HSA-9679191	0.00115686058502	0.210526315789	HMG20B KDM1A RCOR1 PHF21A	Potential therapeutics for SARS
GO:0003714	0.00182039196661	0.315789473684	RCOR2 TRERF1 RCOR3 RERE PHF12 RCOR1	transcription corepressor activity
HPA:0170252	0.00190527229325	0.526315789474	ADNP RCOR3 HMG20B ZMYM3 TRERF1 ZMYM4 KDM1A ZMYM2 PHF12 RCOR1	endometrium 2; cells in endometrial stroma[>=Medium]
CORUM:646	0.00218827065477	0.105263157895	RCOR1 KDM1A	HDAC1-associated protein complex
CORUM:643	0.00218827065477	0.105263157895	RCOR1 KDM1A	CtBP core complex
TF:M07436_1	0.00571531903459	0.684210526316	PHF21A ADNP RCOR2 RCOR3 OVOL2 ZMYM3 TRERF1 ZMYM2 ZMYM4 PWWP2A PHF12 GSE1 RCOR1	Factor: WT1; motif: NNGGGNGGGSGN; match class: 1
GO:0005667	0.00994377494074	0.368421052632	RCOR2 ADNP TRERF1 RCOR3 KDM1A PHF12 RCOR1	transcription regulator complex
REAC:R-HSA-983231	0.013116233271	0.210526315789	HMG20B KDM1A RCOR1 PHF21A	Factors involved in megakaryocyte development and platelet production
TF:M12057_1	0.0147753805588	0.526315789474	RCOR2 RCOR3 ADNP ZMYM3 TRERF1 ZMYM4 KDM1A ZMYM2 GSE1 RCOR1	Factor: ZBP99; motif: GCCCMTCCCCCR; match class: 1
HP:0001182	0.017487036475	0.210526315789	ZMYM2 PHF21A KDM1A ADNP	Tapered finger
TF:M09834_1	0.0229802976739	0.684210526316	PHF21A ADNP RCOR2 RCOR3 OVOL2 ZMYM3 TRERF1 ZMYM2 ZMYM4 PHF12 HMG20B GSE1 RCOR1	Factor: ZNF148; motif: NNNNNNCCNNCCCCTCCCCCACCCN; match class: 1
GO:0045892	0.02304919751	0.473684210526	PHF21A RCOR2 OVOL2 TRERF1 RCOR3 KDM1A ZMYM2 PHF12 RCOR1	negative regulation of DNA-templated transcription
GO:1902679	0.0254085658836	0.473684210526	PHF21A RCOR2 OVOL2 TRERF1 RCOR3 KDM1A ZMYM2 PHF12 RCOR1	negative regulation of RNA biosynthetic process
GO:0003712	0.0274132472444	0.368421052632	RCOR2 TRERF1 RCOR3 KDM1A PHF12 RCOR1 RERE	transcription coregulator activity
TF:M10432_1	0.0328763033098	0.789473684211	PHF21A ADNP RCOR2 RCOR3 OVOL2 ZMYM3 TRERF1 ZMYM2 ZMYM4 ZSCAN5A PHF12 PWWP2A HMG20B GSE1 RCOR1	Factor: MAZ; motif: GGGMGGGGS; match class: 1
CORUM:2160	0.0496196263904	0.0526315789474	KDM1A	AOF2-AR complex

Edges

Protein 1	Protein 2	Score	ProteomeHD
HMG20B	GSE1	1.0	0.058
GSE1	RCOR1	1.0	0.066
HMG20B	RCOR1	1.0	0.082
HMG20B	KDM1A	1.0	0.236
HMG20B	RCOR3	1.0	0.152
RCOR1	KDM1A	1.0	0.496
RCOR3	KDM1A	1.0	0.724
HMG20B	PHF21A	1.0	0.252
ZSCAN5A	ZMYM2	1.0
GSE1	RCOR3	0.999	0.104
RCOR3	RCOR1	0.999	0.32
GSE1	KDM1A	0.999	0.289164179104
ZMYM2	RCOR3	0.999	0.17
PHF21A	RCOR1	0.999	0.076
ZMYM2	ZMYM3	0.999	0.182
ZMYM4	ZMYM2	0.999	0.148
ZMYM4	ZSCAN5A	0.999
PHF21A	RCOR3	0.999	0.084
ZMYM2	RCOR1	0.998	0.116
HMG20B	RCOR2	0.998	0.102
ZMYM3	RCOR3	0.998	0.15
HMG20B	OVOL2	0.997
ZMYM3	RCOR1	0.996	0.098
ADNP	ZMYM3	0.996	0.55
EEF1AKMT4-ECE2	RCOR3	0.996	0.066
ZSCAN5A	RCOR2	0.996
EEF1AKMT4-ECE2	RCOR2	0.995	0.044
ZMYM4	ZMYM3	0.995	0.234
TRERF1	DNTTIP1	0.994
PHF21A	GSE1	0.994	0.1
ZMYM2	KDM1A	0.993	0.4
PHF21A	KDM1A	0.993	0.18
ZSCAN5A	ZMYM3	0.992
ZSCAN5A	KDM1A	0.992
ZSCAN5A	RCOR3	0.991
EEF1AKMT4-ECE2	KDM1A	0.989	0.216
TRERF1	PWWP2A	0.987
ZMYM2	RCOR2	0.986	0.228
RCOR2	KDM1A	0.985	0.102
PWWP2A	DNTTIP1	0.984	0.212
ZSCAN5A	RCOR1	0.98
ZMYM3	KDM1A	0.978	0.474
PHF12	RCOR1	0.978	0.104
ZMYM4	RCOR1	0.976	0.1
ZMYM2	HMG20B	0.974	0.076
RCOR2	RCOR3	0.974	0.07
PWWP2A	RCOR3	0.972	0.104
ZMYM2	TRERF1	0.969
PHF12	TRERF1	0.968
ADNP	ZMYM2	0.967	0.34
HMG20B	PWWP2A	0.967	0.12
PHF12	RCOR3	0.966	0.112
PWWP2A	RCOR1	0.965	0.17
RERE	PWWP2A	0.965	0.108
ADNP	RCOR3	0.964	0.25
PHF12	GSE1	0.964	0.172
GSE1	RCOR2	0.961	0.144
PHF21A	RCOR2	0.961	0.08
OVOL2	KDM1A	0.96
RERE	ZMYM2	0.96	0.132
RCOR2	RCOR1	0.958	0.066
GSE1	PWWP2A	0.957	0.058
PHF12	HMG20B	0.956	0.238
RERE	PHF12	0.956	0.276
ZMYM3	TRERF1	0.939
ZMYM3	HMG20B	0.906	0.162
EEF1AKMT4-ECE2	RCOR1	0.899	0.092
ZMYM4	RCOR3	0.891	0.12
RERE	HMG20B	0.878	0.116
ZMYM3	DNTTIP1	0.877	0.07
PWWP2A	KDM1A	0.871	0.16
RERE	TRERF1	0.87
ZMYM3	PWWP2A	0.863	0.142
PHF12	ZMYM2	0.857	0.362
TRERF1	KDM1A	0.856
PHF12	KDM1A	0.856	0.372
ADNP	ZMYM4	0.855	0.46
RERE	KDM1A	0.85	0.378
ADNP	RCOR1	0.847	0.096
RERE	ZMYM3	0.841	0.13
TRERF1	RCOR3	0.841
TRERF1	RCOR1	0.841
PHF12	PWWP2A	0.835	0.108
HMG20B	TRERF1	0.832
ZMYM3	RCOR2	0.825	0.146
GSE1	TRERF1	0.806
RERE	GSE1	0.793	0.096
ZMYM3	GSE1	0.763	0.096
RERE	RCOR3	0.758	0.106
ADNP	KDM1A	0.75	0.282
OVOL2	RCOR1	0.749
RERE	RCOR1	0.735	0.17
TRERF1	RCOR2	0.73
ZMYM2	PWWP2A	0.725	0.066
RERE	DNTTIP1	0.71	0.07
HMG20B	DNTTIP1	0.71	0.09
ZMYM4	KDM1A	0.686	0.386
OVOL2	RCOR3	0.672
RERE	PHF21A	0.658	0.23
PHF21A	TRERF1	0.637
DNTTIP1	RCOR2	0.605	0.028
DNTTIP1	RCOR1	0.604	0.062
GSE1	DNTTIP1	0.594	0.096
RERE	RCOR2	0.567	0.092
DNTTIP1	RCOR3	0.55	0.07
PHF12	ZMYM3	0.479	0.11
ZMYM2	PHF21A	0.468	0.15
ADNP	RCOR2	0.447	0.084
PHF21A	DNTTIP1	0.443	0.072
PHF12	PHF21A	0.44	0.222
RERE	ADNP	0.436	0.146
ZMYM2	DNTTIP1	0.417	0.062
PHF12	DNTTIP1	0.412	0.134
PHF21A	PWWP2A	0.396	0.118
ZMYM2	GSE1	0.367	0.094
ZMYM4	RCOR2	0.346	0.044
ZMYM3	PHF21A	0.312	0.122
DNTTIP1	KDM1A	0.201	0.146
PHF12	RCOR2	0.19	0.092
PWWP2A	RCOR2	0.143	0.06
ADNP	ZSCAN5A	0.079
ADNP	TRERF1	0.063
ADNP	HMG20B	0.063	0.104
RERE	ZMYM4	0.043	0.164
ADNP	PHF12	0.042	0.33
ADNP	PHF21A	0.041	0.086
ADNP	PWWP2A	0.039	0.116
ZMYM4	HMG20B	0.036	0.168
ADNP	GSE1	0.03	0.1
ZMYM4	GSE1	0.02	0.162
ADNP	DNTTIP1	0.018	0.096
ZMYM4	PHF21A	0.017	0.084
OVOL2	GSE1	0.015
PHF12	ZMYM4	0.014	0.134
ZMYM4	DNTTIP1	0.006	0.072

Related Complexes

Genename	Complexes
ZMYM4	huMAP3_00780.1 huMAP3_01309.1 huMAP3_03699.1 huMAP3_07073.1 huMAP3_07496.1 huMAP3_08464.1 huMAP3_09232.1 huMAP3_09692.1 huMAP3_09963.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_11539.1
RCOR3	huMAP3_02683.1 huMAP3_05204.1 huMAP3_08800.1 huMAP3_08880.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09692.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_15128.1
GSE1	huMAP3_01287.1 huMAP3_05107.1 huMAP3_05699.1 huMAP3_08605.1 huMAP3_08800.1 huMAP3_08865.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09692.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_15128.1
OVOL2	huMAP3_00955.1 huMAP3_01657.1 huMAP3_03935.1 huMAP3_06588.1 huMAP3_07413.1 huMAP3_07917.1 huMAP3_08165.1 huMAP3_09874.1 huMAP3_10258.1 huMAP3_10365.1
ZMYM3	huMAP3_00780.1 huMAP3_07073.1 huMAP3_08464.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09582.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_11539.1
PWWP2A	huMAP3_01287.1 huMAP3_05396.1 huMAP3_05699.1 huMAP3_07709.1 huMAP3_08463.1 huMAP3_08605.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09499.1 huMAP3_09513.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_10472.1 huMAP3_15128.1
RERE	huMAP3_00047.1 huMAP3_01287.1 huMAP3_07585.1 huMAP3_08605.1 huMAP3_08776.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09422.1 huMAP3_09513.1 huMAP3_10027.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_13482.1 huMAP3_15128.1
HMG20B	huMAP3_00955.1 huMAP3_01287.1 huMAP3_08165.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_15128.1
PHF12	huMAP3_00411.1 huMAP3_01287.1 huMAP3_05699.1 huMAP3_06457.1 huMAP3_07709.1 huMAP3_08605.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09513.1 huMAP3_09515.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_13482.1 huMAP3_15128.1
PHF21A	huMAP3_01287.1 huMAP3_02683.1 huMAP3_08605.1 huMAP3_08800.1 huMAP3_08880.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09692.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_15128.1
EEF1AKMT4-ECE2	huMAP3_02683.1 huMAP3_05204.1 huMAP3_08165.1 huMAP3_09874.1 huMAP3_10258.1 huMAP3_10311.1
RCOR1	huMAP3_04507.1 huMAP3_05107.1 huMAP3_05699.1 huMAP3_08605.1 huMAP3_08800.1 huMAP3_08865.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09692.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_15128.1
KDM1A	huMAP3_06588.1 huMAP3_08165.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09874.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_15128.1
TRERF1	huMAP3_01287.1 huMAP3_02407.1 huMAP3_05396.1 huMAP3_06334.1 huMAP3_07709.1 huMAP3_08605.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09513.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_15128.1
ADNP	huMAP3_00075.1 huMAP3_00780.1 huMAP3_01874.1 huMAP3_04478.1 huMAP3_06802.1 huMAP3_07073.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08464.1 huMAP3_09046.1 huMAP3_09071.1 huMAP3_09232.1 huMAP3_09582.1 huMAP3_09707.1 huMAP3_09963.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_11539.1
DNTTIP1	huMAP3_01287.1 huMAP3_02407.1 huMAP3_05396.1 huMAP3_06334.1 huMAP3_07709.1 huMAP3_08605.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09513.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_11690.1
ZSCAN5A	huMAP3_00780.1 huMAP3_05699.1 huMAP3_08464.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09692.1 huMAP3_10258.1 huMAP3_10311.1
ZMYM2	huMAP3_00780.1 huMAP3_07073.1 huMAP3_08464.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09582.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_12566.1 huMAP3_15128.1
RCOR2	huMAP3_02683.1 huMAP3_05204.1 huMAP3_08165.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_12062.1 huMAP3_15128.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10258.1