hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10270.1

Confidence: Medium High

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Genename	Protein Name	Uniprot Annotation Score	Links
FBXO40	F-box only protein 40 (Muscle disease-related protein)	4	UniProt NCBI
IQGAP1	Ras GTPase-activating-like protein IQGAP1 (p195)	5	UniProt NCBI
IQGAP2	Ras GTPase-activating-like protein IQGAP2	5	UniProt NCBI
JMY	Junction-mediating and -regulatory protein	5	UniProt NCBI
MYH10	Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)	5	UniProt NCBI
MYH14	Myosin-14 (Myosin heavy chain 14) (Myosin heavy chain, non-muscle IIc) (Non-muscle myosin heavy chain IIc) (NMHC II-C)	5	UniProt NCBI
MYH9	Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)	5	UniProt NCBI
MYL12B	Myosin regulatory light chain 12B (MLC-2A) (MLC-2) (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) (SHUJUN-1)	5	UniProt NCBI
MYL3	Myosin light chain 3 (Cardiac myosin light chain 1) (CMLC1) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular myosin alkali light chain) (Ventricular myosin light chain 1) (VLCl) (Ventricular/slow twitch myosin alkali light chain) (MLC-lV/sb)	5	UniProt NCBI
MYL6	Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)	5	UniProt NCBI

Showing 1 to 10 of 12 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-5627117	4.48164941267e-10	0.416666666667	MYH14 MYL12B MYH10 MYL6 MYH9	RHO GTPases Activate ROCKs
REAC:R-HSA-416572	4.48164941267e-10	0.416666666667	MYH14 MYL12B MYH10 MYL6 MYH9	Sema4D induced cell migration and growth-cone collapse
REAC:R-HSA-5625900	4.48164941267e-10	0.416666666667	MYH14 MYL12B MYH10 MYL6 MYH9	RHO GTPases activate CIT
REAC:R-HSA-5627123	5.97314512092e-10	0.416666666667	MYH14 MYL12B MYH10 MYL6 MYH9	RHO GTPases activate PAKs
REAC:R-HSA-400685	1.29482408489e-09	0.416666666667	MYH14 MYL12B MYH10 MYL6 MYH9	Sema4D in semaphorin signaling
REAC:R-HSA-3928663	2.52820160423e-09	0.416666666667	MYH14 MYL12B MYH10 MYL6 MYH9	EPHA-mediated growth cone collapse
KEGG:04530	3.04301041155e-08	0.5	MYL12B MYH9 MYH14 SYNPO MYH10 MYL6	Tight junction
GO:0015629	4.61603524673e-08	0.75	MYL3 IQGAP2 MYL12B MYH9 MYH14 SYNPO IQGAP1 MYH10 MYL6	actin cytoskeleton
KEGG:04814	7.68391335435e-08	0.5	MYL3 MYL12B MYH9 MYH14 MYL6 MYH10	Motor proteins
REAC:R-HSA-373755	1.89892922681e-07	0.416666666667	MYH14 MYL12B MYH10 MYL6 MYH9	Semaphorin interactions

Showing 1 to 10 of 47 entries

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Protein 1	Protein 2	Score	ProteomeHD
MYH9	MYL6	0.999	0.428674157303
MYL12B	MYH10	0.998	0.124
MYH9	MYL3	0.998	0.564
MYL3	MYH10	0.998	0.044
MYL6	MYH10	0.996	0.176307692308
MYH9	MYL12B	0.996	0.916
MYH14	MYL6	0.995
IQGAP2	MYL6	0.995	0.128
MYL6	MYL12B	0.993	0.146
MYL3	IQGAP1	0.992	0.174

Showing 1 to 10 of 51 entries

Related Complexes

Genename	Complexes
PTGR3	huMAP3_02015.1 huMAP3_03395.1 huMAP3_03551.1 huMAP3_05056.1 huMAP3_06026.1 huMAP3_09870.1 huMAP3_10244.1 huMAP3_10270.1 huMAP3_12775.1
MYH14	huMAP3_02178.1 huMAP3_03169.1 huMAP3_03184.1 huMAP3_05543.1 huMAP3_07968.1 huMAP3_08039.1 huMAP3_09441.1 huMAP3_10270.1 huMAP3_15295.1
FBXO40	huMAP3_02178.1 huMAP3_08039.1 huMAP3_10270.1 huMAP3_15295.1
MYH10	huMAP3_05057.1 huMAP3_06017.1 huMAP3_07666.1 huMAP3_09789.1 huMAP3_10270.1
MYH9	huMAP3_01606.1 huMAP3_05057.1 huMAP3_06017.1 huMAP3_07666.1 huMAP3_09789.1 huMAP3_10270.1 huMAP3_15295.1
SYNPO	huMAP3_01606.1 huMAP3_03689.1 huMAP3_04826.1 huMAP3_05057.1 huMAP3_05614.1 huMAP3_06017.1 huMAP3_07776.1 huMAP3_09555.1 huMAP3_09579.1 huMAP3_10270.1 huMAP3_10784.1 huMAP3_11076.1 huMAP3_12531.1 huMAP3_15295.1
MYL6	huMAP3_02370.1 huMAP3_03169.1 huMAP3_05350.1 huMAP3_05543.1 huMAP3_06098.1 huMAP3_06531.1 huMAP3_07968.1 huMAP3_08039.1 huMAP3_09441.1 huMAP3_10270.1
JMY	huMAP3_02015.1 huMAP3_03395.1 huMAP3_05056.1 huMAP3_06017.1 huMAP3_06026.1 huMAP3_06531.1 huMAP3_09870.1 huMAP3_10270.1
MYL12B	huMAP3_02370.1 huMAP3_06098.1 huMAP3_06531.1 huMAP3_08039.1 huMAP3_09542.1 huMAP3_10270.1
MYL3	huMAP3_02370.1 huMAP3_03169.1 huMAP3_05350.1 huMAP3_05543.1 huMAP3_06098.1 huMAP3_06531.1 huMAP3_08039.1 huMAP3_09789.1 huMAP3_10270.1 huMAP3_15295.1
IQGAP2	huMAP3_00809.1 huMAP3_02370.1 huMAP3_02834.1 huMAP3_05543.1 huMAP3_06531.1 huMAP3_08039.1 huMAP3_08200.1 huMAP3_09441.1 huMAP3_10270.1 huMAP3_10273.1 huMAP3_10665.1 huMAP3_12336.1 huMAP3_13036.1
IQGAP1	huMAP3_02370.1 huMAP3_05543.1 huMAP3_06098.1 huMAP3_06445.1 huMAP3_06531.1 huMAP3_08039.1 huMAP3_10270.1